Cardiovascular disease biomarkers derived from circulating cell-free DNA methylation

Autor: Cuadrat, R.R.C., Kratzer, A., Arnal, H.G., Rathgeber, A.C., Wreczycka, K., Blume, A., Gündüz, I.B., Ebenal, V., Mauno, T., Osberg, B., Moobed, M., Hartung, J., Jakobs, K., Seppelt, C., Meteva, D., Haghikia, A., Leistner, D.M., Landmesser, Ulf, Akalin, A.

Acute coronary syndrome (ACS) remains a major cause of worldwide mortality. The syndrome occurs when blood flow to the heart muscle is decreased or blocked, causing muscle tissues to die or malfunction. There are three main types of ACS: Non-ST-eleva

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http://edoc.mdc-berlin.de/23562/2/23562suppl.zip

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Cardiovascular disease biomarkers derived from circulating cell-free DNA methylation.

Autor: Cuadrat RRC; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany., Kratzer A; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany., Arnal HG; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany., Rathgeber AC; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany., Wreczycka K; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany., Blume A; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany., Gündüz IB; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany., Ebenal V; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany., Mauno T; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany., Osberg B; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany., Moobed M; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany., Hartung J; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany., Jakobs K; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany., Seppelt C; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany.; Universitätsklinikum Frankfurt am Main, Medizinische Klinik 3, Klinik für Kardiologie und Angiologie, Germany., Meteva D; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany., Haghikia A; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany., Leistner DM; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany.; Universitätsklinikum Frankfurt am Main, Medizinische Klinik 3, Klinik für Kardiologie und Angiologie, Germany., Landmesser U; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiology, Campus Benjamin Franklin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany., Akalin A; Bioinformatics & Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine Berlin, Berlin, Germany.

Publikováno v: NAR genomics and bioinformatics [NAR Genom Bioinform] 2023 Jun 28; Vol. 5 (2), pp. lqad061. Date of Electronic Publication: 2023 Jun 28 (Print Publication: 2023).