Zobrazeno 1 - 10
of 416
pro vyhledávání: '"Wray Nr"'
Autor:
Goddard ME, Wray NR
Publikováno v:
Genetics Selection Evolution, Vol 26, Iss 5, Pp 431-451 (1994)
Externí odkaz:
https://doaj.org/article/17a020eb9a854da291e4bdb0f98e0393
Autor:
Yap, CX, Henders, AK, Alvares, GA, Giles, C, Huynh, K, Nguyen, A, Wallace, L, McLaren, T, Yang, Y, Hernandez, LM, Gandal, MJ, Hansell, NK, Cleary, D, Grove, R, Hafekost, C, Harun, A, Holdsworth, H, Jellett, R, Khan, F, Lawson, LP, Leslie, J, Levis Frenk, M, Masi, A, Mathew, NE, Muniandy, M, Nothard, M, Miller, JL, Nunn, L, Strike, LT, Cadby, G, Moses, EK, Busselton Health Study Investigators, de Zubicaray, GI, Thompson, PM, McMahon, KL, Wright, MJ, Visscher, PM, Dawson, PA, Dissanayake, C, Eapen, V, Heussler, HS, Whitehouse, AJO, Meikle, PJ, Wray, NR, Gratten, J
Autism omics research has historically been reductionist and diagnosis centric, with little attention paid to common co-occurring conditions (for example, sleep and feeding disorders) and the complex interplay between molecular profiles and neurodeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::5c5f09ea1e21c05a34d864e78ce33c61
https://hdl.handle.net/10453/170564
https://hdl.handle.net/10453/170564
Autor:
van Rheenen, W, van der Spek, RAA, Bakker, MK, van Vugt, JJFA, Hop, PJ, Zwamborn, RAJ, de Klein, N, Westra, HJ, Bakker, OB, Deelen, P, Shireby, G, Hannon, E, Moisse, M, Baird, D, Restuadi, R, Dolzhenko, E, Dekker, AM, Gawor, K, Westeneng, HJ, Tazelaar, GHP, van Eijk, KR, Kooyman, M, Byrne, RP, Doherty, M, Heverin, M, Al Khleifat, A, Iacoangeli, A, Shatunov, A, Ticozzi, N, Cooper-Knock, J, Smith, BN, Gromicho, M, Chandran, S, Pal, S, Morrison, KE, Shaw, PJ, Hardy, J, Orrell, RW, Sendtner, M, Meyer, T, Basak, N, van der Kooi, AJ, Ratti, A, Fogh, I, Gellera, C, Lauria, G, Corti, S, Cereda, C, Sproviero, D, Soraru, G, Siciliano, G, Filosto, M, Padovani, A, Chio, A, Calvo, A, Moglia, C, Brunetti, M, Canosa, A, Grassano, M, Beghi, E, Pupillo, E, Logroscino, G, Nefussy, B, Osmanovic, A, Nordin, A, Lerner, Y, Zabari, M, Gotkine, M, Baloh, RH, Bell, S, Vourc'h, P, Corcia, P, Couratier, P, Millecamps, S, Meininger, V, Salachas, F, Pardina, JMS, Assialioui, A, Rojas-Garcia, R, Dion, PA, Ross, JP, Ludolph, AC, Weishaupt, JH, Brenner, D, Freischmidt, A, Bensimon, G, Brice, A, Durr, A, Payan, CAM, Saker-Delye, S, Wood, NW, Topp, S, Rademakers, R, Tittmann, L, Lieb, W, Franke, A, Ripke, S, Braun, A, Kraft, J, Whiteman, DC, Olsen, CM, Uitterlinden, AG, Hofman, A, Rietschel, M, Cichon, S, Nothen, MM, Amouyel, P, Comi, G, Riva, N, Lunetta, C, Gerardi, F, Cotelli, MS, Rinaldi, F, Chiveri, L, Guaita, MC, Perrone, P, Diamanti, L, Ferrarese, C, Tremolizzo, L, Delodovici, ML, Bono, G, Manera, U, Vasta, R, Bombaci, A, Casale, F, Fuda, G, Salamone, P, Iazzolino, B, Peotta, L, Cugnasco, P, De Marco, G, Torrieri, MC, Palumbo, F, Gallone, S, Barberis, M, Sbaiz, L, Gentile, S, Mauro, A, De Marchi, F, D'Alfonso, S, Bertolotto, A, Gionco, M, Leotta, D, Odddenino, E, Imperiale, D, Cavallo, R, Pignatta, P, De Mattei, M, Geda, C, Papurello, DM, Gusmaroli, G, Comi, C, Labate, C, Ruiz, L, Ferrandi, D, Rota, E, Aguggia, M, Di Vito, N, Meineri, P, Ghiglione, P, Launaro, N, Dotta, M, Di Sapio, A, Giardini, G, Tiloca, C, Peverelli, S, Taroni, F, Pensato, V, Castellotti, B, Comi, GP, Del Bo, R, Ceroni, M, Gagliardi, S, Corrado, L, Mazzini, L, Raggi, F, Simoncini, C, Lo Gerfo, A, Inghilleri, M, Ferlini, A, Simone, IL, Passarella, B, Guerra, V, Zoccolella, S, Nozzoli, C, Mundi, C, Leone, M, Zarrelli, M, Tamma, F, Valluzzi, F, Calabrese, G, Boero, G, Rini, A, Traynor, BJ, Singleton, AB, Neto, MM, Cauchi, RJ, Ophoff, RA, Wiedau-Pazos, M, Lomen-Hoerth, C, van Deerlin, VM, Grosskreutz, J, Roediger, A, Gaur, N, Jork, A, Barthel, T, Theele, E, Ilse, B, Stubendorff, B, Witte, OW, Steinbach, R, Hubner, CA, Graff, C, Brylev, L, Fominykh, V, Demeshonok, V, Ataulina, A, Rogelj, B, Koritnik, B, Zidar, J, Ravnik-Glavac, M, Glavac, D, Stevic, Z, Drory, V, Povedano, M, Blair, IP, Kiernan, MC, Benyamin, B, Henderson, RD, Furlong, S, Mathers, S, McCombe, PA, Needham, M, Ngo, ST, Nicholson, GA, Pamphlett, R, Rowe, DB, Steyn, FJ, Williams, KL, Mather, KA, Sachdev, PS, Henders, AK, Wallace, L, de Carvalho, M, Pinto, S, Petri, S, Weber, M, Rouleau, GA, Silani, V, Curtis, CJ, Breen, G, Glass, JD, Brown, RH, Landers, JE, Shaw, CE, Andersen, PM, Groen, EJN, van Es, MA, Pasterkamp, RJ, Fan, DS, Garton, FC, McRae, AF, Smith, GD, Gaunt, TR, Eberle, MA, Mill, J, McLaughlin, RL, Hardiman, O, Kenna, KP, Wray, NR, Tsai, EL, Runz, H, Franke, L, Al-Chalabi, A, Van Damme, P, van den Berg, LH, Veldink, JH, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium
Publikováno v:
NATURE GENETICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::14d0bed056ea6e9b6c5550b9e67e8ce3
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8163
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8163
Autor:
Yap, CX, Henders, AK, Alvares, GA, Wood, DLA, Krause, L, Tyson, GW, Restuadi, R, Wallace, L, McLaren, T, Hansell, NK, Cleary, D, Grove, R, Hafekost, C, Harun, A, Holdsworth, H, Jellett, R, Khan, F, Lawson, LP, Leslie, J, Frenk, ML, Masi, A, Mathew, NE, Muniandy, M, Nothard, M, Miller, JL, Nunn, L, Holtmann, G, Strike, LT, de Zubicaray, GI, Thompson, PM, McMahon, KL, Wright, MJ, Visscher, PM, Dawson, PA, Dissanayake, C, Eapen, V, Heussler, HS, McRae, AF, Whitehouse, AJO, Wray, NR, Gratten, J
There is increasing interest in the potential contribution of the gut microbiome to autism spectrum disorder (ASD). However, previous studies have been underpowered and have not been designed to address potential confounding factors in a comprehensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::42a4353e10e79c4bca4598a1f942935e
https://hdl.handle.net/10453/152551
https://hdl.handle.net/10453/152551
Autor:
Phil Lee, Richard Anney, Pieter J. Hoekstra, Barbara Franke, Geschwind Dh, Michael C. Neale, Yen-Chen Anne Feng, Edwin H. Cook, Anttila, E Stahl, Borglum Ad, Kenneth S. Kendler, Santangelo Sl, Wray Nr, Danielle Posthuma, Carol A. Mathews, Sintia Iole Belangero, Amanda B Zheutlin, Cynthia M. Bulik, Jeremiah M. Scharf, Laramie E. Duncan, Luis Augusto Rohde, Jacob Rosenthal, Anna Keski-Rahkonen, Stein Mb, Fanous Ah, Zhaozhong Zhu, Karen S. Mitchell, J Kaprio, Breen G, Michel G. Nivard, G. Kirov, John I. Nurnberger, Patrick F. Sullivan, Daly Mj, Michael Conlon O'Donovan, Andreassen Oa, Hyejung Won, Wang Mm, Faraone Sv, Mattheisen M, Benjamin M. Neale, Gelernter J, Smoller Jw, Henry R. Kranzler, Thornton Lm, Clement C. Zai, Ripke S, Elliot M. Tucker-Drob, Howard J. Edenberg, Lewis Cm, McIntosh Am, Tobias Banaschewski, Dongmei Yu, Andrew D. Grotzinger, Walters Jt, Raymond K. Walters, Giovanni Coppola, Jurjen J. Luykx
SummaryGenetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed a meta-analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98ca48d606cd4e120d8e0a0c6fbb9d5
Autor:
Bigdeli, T. B, Ripke, S, Bacanu, Sa, Lee, S. H, Wray, Nr, Gejman, P. V, Rietschel, M, Cichon, S, St Clair, D, Corvin, A, Kirov, G, Mcquillin, A, Gurling, H, Rujescu, D, Andreassen, O. A, Werge, T, Blackwood, D. H. R, Pato, C. N, Pato, M. T, Malhotra, A. K, O'Donovan, M. C, Kendler, K. S, Fanous, A. H, Neale, Bm, Walters, Jt, Farh, Kh, Holmans, Pa, Lee, P, Bulik Sullivan, B, Collier, Da, Huang, H, Pers, Th, Agartz, I, Agerbo, E, Albus, M, Alexander, M, Amin, F, Begemann, M, Belliveau, Ra, Bene, J, Bergen, Se, Bevilacqua, E, Bigdeli, Tb, Black, Dw, Børglum, Ad, Bruggeman, R, Buccola, Ng, Buckner, Rl, Byerley, W, Cahn, W, Cai, G, Campion, D, Cantor, Rm, Carr, Vj, Carrera, N, Catts, Sv, Chambert, Kd, Chan, Rc, Chen, Ry, Chen, Ey, Cheng, W, Cheung, Ef, Chong, Sa, Cloninger, C, Cohen, D, Cohen, N, Cormican, P, Craddock, N, Crowley, Jj, Curtis, D, Davidson, M, Davis, Kl, Degenhardt, F, Del, Favero, J, Delisi, Le, Demontis, D, Dikeos, D, Dinan, T, Djurovic, S, Donohoe, G, Drapeau, E, Duan, J, Dudbridge, F, Durmishi, N, Eichhammer, P, Eriksson, J, Escott Price, V, Essioux, L, Fanous, Ah, Farrell, Ms, Frank, J, Franke, L, Freedman, R, Freimer, Nb, Friedl, M, Friedman, Ji, Fromer, M, Genovese, G, Georgieva, L, Gershon, Es, Giegling, I, Giusti Rodríguez, P, Godard, S, Goldstein, Ji, Golimbet, V, Gopal, S, Gratten, J, Grove, J, Haan, De, L, Hammer, C, Hamshere, Ml, Hansen, M, Hansen, T, Haroutunian, V, Hartmann, Am, Henskens, Fa, Herms, S, Hirschhorn, Jn, Hoffmann, P, Hofman, A, Hollegaard, Mv, Hougaard, Dm, Ikeda, M, Joa, I, Julìa, A, Kahn, Rs, Kalaydjieva, L, Karachanak Yankova, S, Karjalainen, J, Kavanagh, D, Keller, Mc, Kelly, Bj, Kennedy, Jl, Khrunin, A, Kim, Y, Klovins, J, Knowles, Ja, Konte, B, Kucinskas, V, Kucinskiene, Za, Kuzelova Ptackova, H, Kähler, Ak, Laurent, C, Keong, Jl, Lee, S, Legge, Se, Lerer, B, Li, M, Li, T, Liang, Ky, Lieberman, J, Limborska, S, Loughland, Cm, Lubinski, J, Lönnqvist, J, Macek, M, Magnusson, Pk, Maher, Bs, Maier, W, Mallet, J, Marsal, S, Mattheisen, M, Mattingsdal, M, Mccarley, Rw, Mcdonald, C, Mcintosh, Am, Meier, S, Meijer, Cj, Melegh, B, Melle, I, Mesholam Gately, Ri, Metspalu, A, Michie, Pt, Milani, L, Milanova, V, Mokrab, Y, Morris, Dw, Mors, O, Mortensen, Pb, Murphy, Kc, Murray, Rm, Myin Germeys, I, Müller Myhsok, B, Nelis, M, Nenadic, I, Nertney, Da, Nestadt, G, Nicodemus, Kk, Nikitina Zake, L, Nisenbaum, L, Nordin, A, O'Callaghan, E, O'Dushlaine, C, O'Neill, F, Sy, Oh, Olincy, A, Olsen, L, Jv, Os, Pantelis, C, Papadimitriou, Gn, Papiol, S, Parkhomenko, E, Pato, Mt, Paunio, T, Pejovic Milovancevic, M, Perkins, Do, Pietiläinen, O, Pimm, J, Pocklington, Aj, Powell, J, Price, A, Pulver, Ae, Purcell, Sm, Quested, D, Rasmussen, Hb, Reichenberg, A, Reimers, Ma, Richards, Al, Roffman, Jl, Roussos, P, Ruderfer, Dm, Salomaa, V, Sanders, Ar, Schall, U, Schubert, Cr, Schulze, Tg, Schwab, Sg, Scolnick, Em, Scott, Rj, Seidman, Lj, Shi, J, Sigurdsson, E, Silagadze, T, Silverman, Jm, Sim, K, Slominsky, P, Smoller, Jw, Hc, So, Spencer, Cc, Stahl, Ea, Stefansson, H, Steinberg, S, Stogmann, E, Straub, Re, Strengman, E, Strohmaier, J, Stroup, T, Subramaniam, M, Suvisaari, J, Svrakic, Dm, Szatkiewicz, Jp, Söderman, E, Thirumalai, S, Toncheva, D, Tooney, Pa, Tosato, Sarah, Veijola, J, Waddington, J, Walsh, D, Wang, D, Wang, Q, Webb, Bt, Weiser, M, Wildenauer, Db, Williams, Nm, Williams, S, Witt, Sh, Wolen, Ar, Wong, Eh, Wormley, Bk, Jq, Wu, Hs, Xi, Zai, Cc, Zheng, X, Zimprich, F, Stefansson, K, Visscher, Pm, Adolfsson, R, Andreassen, Oa, Blackwood, Dh, Bramon, E, Buxbaum, Jd, Darvasi, A, Domenici, E, Ehrenreich, H, Esko, T, Gejman, Pv, Gill, M, Hultman, Cm, Iwata, N, Jablensky, Av, Jönsson, Eg, Kendler, Ks, Knight, J, Lencz, T, Levinson, Df, Qs, Li, Liu, J, Malhotra, Ak, Mccarroll, Sa, Moran, Jl, Mowry, Bj, Nöthen, Mm, Ophoff, Ra, Owen, Mj, Palotie, A, Pato, Cn, Petryshen, Tl, Posthuma, D, Riley, Bp, Sham, Pc, Sklar, P, Clair, Ds, Weinberger, Dr, Wendland, Jr, Daly, Mj, Sullivan, Pf, O'Donovan, Mc
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 276-289. Wiley-Liss Inc.
ISSUE=171B;STARTPAGE=276;ENDPAGE=289;ISSN=1552-4841;TITLE=American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American journal of medical genetics. Part B, Neuropsychiatric genetics, 171BB(2), 276-289. Wiley-Liss Inc.
Bigdeli, T B, Ripke, S, Bacanu, S A, Lee, S H, Schizophrenia Working Group of the Psychiatric Genomics, U & Posthuma, D 2016, ' Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, no. 171B, 2, pp. 276-289 . https://doi.org/10.1002/ajmg.b.32402
American Journal of Medical Genetics Part B-neuropsychiatric Genetics, 171(2), 276-289. Wiley
American journal of medical genetics: part B: neuropsychiatric genetics
ISSUE=171B;STARTPAGE=276;ENDPAGE=289;ISSN=1552-4841;TITLE=American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American journal of medical genetics. Part B, Neuropsychiatric genetics, 171BB(2), 276-289. Wiley-Liss Inc.
Bigdeli, T B, Ripke, S, Bacanu, S A, Lee, S H, Schizophrenia Working Group of the Psychiatric Genomics, U & Posthuma, D 2016, ' Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, no. 171B, 2, pp. 276-289 . https://doi.org/10.1002/ajmg.b.32402
American Journal of Medical Genetics Part B-neuropsychiatric Genetics, 171(2), 276-289. Wiley
American journal of medical genetics: part B: neuropsychiatric genetics
Genome-wide association studies (GWAS) of schizophrenia have yielded more than 100 common susceptibility variants, and strongly support a substantial polygenic contribution of a large number of small allelic effects. It has been hypothesized that fam
Autor:
Martin, J, Walters, RK, Demontis, D, Mattheisen, M, Lee, SH, Robinson, E, Brikell, I, Ghirardi, L, Larsson, H, Lichtenstein, P, Eriksson, N, 23andMe Research Team, Psychiatric Genomics Consortium: ADHD Subgroup, iPSYCH–Broad ADHD Workgroup, Werge, T, Mortensen, PB, Pedersen, MG, Mors, O, Nordentoft, M, Hougaard, DM, Bybjerg-Grauholm, J, Wray, NR, Franke, B, Faraone, SV, O’Donovan, MC, Thapar, A, Børglum, AD, Neale, BM
Background Attention-deficit/hyperactivity disorder (ADHD) shows substantial heritability and is two to seven times more common in male individuals than in female individuals. We examined two putative genetic mechanisms underlying this sex bias: sex-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2d515cf34be85f45d2a4055dae056327
https://www.ncbi.nlm.nih.gov/pubmed/29325848
https://www.ncbi.nlm.nih.gov/pubmed/29325848
Autor:
Gusev, A, Lee, Sh, SWE SCZ, Consortium, O'Dushlaine, Cgusev, Trynka, G, Finucane, H, Vilhjálmsson, Bj, Xu, H, Zang, C, Ripke, S, Bulik Sullivan, B, Stahl, E, Schizophrenia, Working, Neale, Bm, Corvin, A, Walters, Jt, Farh, Kh, Holmans, Pa, Lee, P, Collier, Da, Huang, H, Pers, Th, Agartz, I, Agerbo, E, Albus, M, Alexander, M, Amin, F, Bacanu, Sa, Begemann, M, Belliveau, Ra, Bene, J, Bergen, Se, Bevilacqua, E, Bigdeli, Tb, Black, Dw, Børglum, Ad, Bruggeman, R, Buccola, Ng, Buckner, Rl, Byerley, W, Cahn, W, Cai, G, Campion, D, Cantor, Rm, Carr, Vj, Carrera, N, Catts, Sv, Chambert, Kd, Chan, Rc, Chen, Ry, Chen, Ey, Cheng, W, Cheung, Ef, Chong, Sa, Cloninger, Cr, Cohen, D, Cohen, N, Cormican, P, Craddock, N, Crowley, Jj, Curtis, D, Davidson, M, Davis, Kl, Degenhardt, F, Del, Favero, Delisi, Le, Demontis, D, Dikeos, D, Dinan, T, Djurovic, S, Donohoe, G, Drapeau, E, Duan, J, Dudbridge, F, Durmishi, N, Eichhammer, P, Eriksson, J, Escott Price, V, Essioux, L, Fanous, Ah, Farrell, Ms, Frank, J, Franke, L, Freedman, R, Freimer, Nb, Friedl, M, Friedman, Ji, Fromer, M, Genovese, G, Georgieva, L, Gershon, Es, Giegling, I, Giusti Rodrguez, P, Godard, S, Goldstein, Ji, Golimbet, V, Gopal, S, Gratten, J, Grove, J, Haan, De, Hammer, C, Hamshere, Ml, Hansen, M, Hansen, T, Haroutunian, V, Hartmann, Am, Henskens, Fa, Herms, S, Hirschhorn, Jn, Hoffmann, P, Hofman, A, Hollegaard, Mv, Hougaard, Dm, Ikeda, M, Joa, I, Julià, A, Kahn, Rs, Kalaydjieva, L, Karachanak Yankova, S, Karjalainen, J, Kavanagh, D, Keller, Mc, Kelly, Bj, Kennedy, Jl, Khrunin, A, Kim, Y, Klovins, J, Knowles, Ja, Konte, B, Kucinskas, V, Kucinskiene, Za, Kuzelova Ptackova, H, Kähler, Ak, Laurent, C, Keong, Jl, Legge, Se, Lerer, B, Li, M, Li, T, Liang, Ky, Lieberman, J, Limborska, S, Loughland, Cm, Lubinski, J, Lnnqvist, J, Macek, M, Magnusson, Pk, Maher, Bs, Maier, W, Mallet, J, Marsal, S, Mattheisen, M, Mattingsdal, M, Mccarley, Rw, Mcdonald, C, Mcintosh, Am, Meier, S, Meijer, Cj, Melegh, B, Melle, I, Mesholam Gately, Ri, Metspalu, A, Michie, Pt, Milani, L, Milanova, V, Mokrab, Y, Morris, Dw, Mors, O, Mortensen, Pb, Murphy, Kc, Murray, Rm, Myin Germeys, I, Mller Myhsok, B, Nelis, M, Nenadic, I, Nertney, Da, Nestadt, G, Nicodemus, Kk, Nikitina Zake, L, Nisenbaum, L, Nordin, A, O'Callaghan, E, O'Dushlaine, C, O'Neill, Fa, Sy, Oh, Olincy, A, Olsen, L, Van, Os, Pantelis, C, Papadimitriou, Gn, Papiol, S, Parkhomenko, E, Pato, Mt, Paunio, T, Pejovic Milovancevic, M, Perkins, Do, Pietilinen, O, Pimm, J, Pocklington, Aj, Powell, J, Price, A, Pulver, Ae, Purcell, Sm, Quested, D, Rasmussen, Hb, Reichenberg, A, Reimers, Ma, Richards, Al, Roffman, Jl, Roussos, P, Ruderfer, Dm, Salomaa, V, Sanders, Ar, Schall, U, Schubert, Cr, Schulze, Tg, Schwab, Sg, Scolnick, Em, Scott, Rj, Seidman, Lj, Shi, J, Sigurdsson, E, Silagadze, T, Silverman, Jm, Sim, K, Slominsky, P, Smoller, Jw, Hc, So, Spencer, Cc, Stahl, Ea, Stefansson, H, Steinberg, S, Stogmann, E, Straub, Re, Strengman, E, Strohmaier, J, Stroup, Ts, Subramaniam, M, Suvisaari, J, Svrakic, Dm, Szatkiewicz, Jp, Sderman, E, Thirumalai, S, Toncheva, D, Tooney, Pa, Tosato, Sarah, Veijola, J, Waddington, J, Walsh, D, Wang, D, Wang, Q, Webb, Bt, Weiser, M, Wildenauer, Db, Williams, Nm, Williams, S, Witt, Sh, Wolen, Ar, Wong, Eh, Wormley, Bk, Jq, Wu, Hs, Xi, Zai, Cc, Zheng, X, Zimprich, F, Wray, Nr, Stefansson, K, Visscher, Pm, Adolfsson, R, Andreassen, Oa, Blackwood, Dh, Bramon, E, Buxbaum, Jd, Brglum, Ad, Cichon, S, Darvasi, A, Domenici, E, Ehrenreich, H, Esko, T, Gejman, Pv, Gill, M, Gurling, H, Hultman, Cm, Iwata, N, Jablensky, Av, Jönsson, Eg, Kendler, Ks, Kirov, G, Knight, J, Lencz, T, Levinson, Df, Qs, Li, Liu, J, Malhotra, Ak, Mccarroll, Sa, Mcquillin, A, Moran, Jl, Mowry, Bj, Nthen, Mm, Ophoff, Ra, Owen, Mj, Palotie, A, Pato, Cn, Petryshen, Tl, Posthuma, D, Rietschel, M, Riley, Bp, Rujescu, D, Sham, Pc, Sklar, P, Clair, St, Weinberger, Dr, Wendland, Jr, Werge, T, Daly, Mj, Sullivan, Pf, O'Donovan, Mc, Chambert, K, Akterin, S, Bergen, S, Ruderfer, D, Scolnick, E, Purcell, S, Mccarroll, S, Daly, M, Pasaniuc, B, Raychaudhuri, S, Price, Al
Publikováno v:
American journal of human genetics, 95(5), 535-552. Cell Press
American Journal of Human Genetics, 95(5), 535-52. Cell Press
Gusev, A, Lee, S H, Trynka, G, Finucane, H, Vilhjálmsson, B J, Xu, H, Zang, C, Ripke, S, Bulik-Sullivan, B, Stahl, E, Kähler, A K, Hultman, C M, Purcell, S M, McCarroll, S A, Daly, M, Pasaniuc, B, Sullivan, P F, Neale, B M, Wray, N R, Raychaudhuri, S, Price, A L & Schizophrenia Working Group of the Psychiatric Genomics Consortium (Manuel Mattheisen and Jakob Grove, members) 2014, ' Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases ', American Journal of Human Genetics, vol. 95, no. 5, pp. 535-52 . https://doi.org/10.1016/j.ajhg.2014.10.004
Gusev, A, Lee, S H, Trynka, G, Finucane, H, Vilhjálmsson, B J, Xu, H, Zang, Z, Ripke, S, Bulik-Sullivan, B K, Stahl, E, Kähler, A K, Hultman, C M, Purcell, S M, McCarroll, S A, Daly, M, Pasaniuc, B, Sullivan, P F, Neale, B M, Wray, N R, Raychaudhuri, S & Price, A L 2014, ' Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. ', American Journal of Human Genetics, vol. 95, no. 5, pp. 535-552 . https://doi.org/10.1016/j.ajhg.2014.10.004
The American Journal of Human Genetics
ResearcherID
American Journal of Human Genetics, 95(5), 535-552. Cell Press
American Journal of Human Genetics, 95(5), 535-52. Cell Press
Gusev, A, Lee, S H, Trynka, G, Finucane, H, Vilhjálmsson, B J, Xu, H, Zang, C, Ripke, S, Bulik-Sullivan, B, Stahl, E, Kähler, A K, Hultman, C M, Purcell, S M, McCarroll, S A, Daly, M, Pasaniuc, B, Sullivan, P F, Neale, B M, Wray, N R, Raychaudhuri, S, Price, A L & Schizophrenia Working Group of the Psychiatric Genomics Consortium (Manuel Mattheisen and Jakob Grove, members) 2014, ' Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases ', American Journal of Human Genetics, vol. 95, no. 5, pp. 535-52 . https://doi.org/10.1016/j.ajhg.2014.10.004
Gusev, A, Lee, S H, Trynka, G, Finucane, H, Vilhjálmsson, B J, Xu, H, Zang, Z, Ripke, S, Bulik-Sullivan, B K, Stahl, E, Kähler, A K, Hultman, C M, Purcell, S M, McCarroll, S A, Daly, M, Pasaniuc, B, Sullivan, P F, Neale, B M, Wray, N R, Raychaudhuri, S & Price, A L 2014, ' Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. ', American Journal of Human Genetics, vol. 95, no. 5, pp. 535-552 . https://doi.org/10.1016/j.ajhg.2014.10.004
The American Journal of Human Genetics
ResearcherID
American Journal of Human Genetics, 95(5), 535-552. Cell Press
Regulatory and coding variants are known to be enriched with associations identified by genome-wide association studies (GWASs) of complex disease, but their contributions to trait heritability are currently unknown. We applied variance-component met
Autor:
Willems, SM, Wright, DJ, Day, FR, Trajanoska, K, Joshi, PK, Morris, JA, Matteini, AM, Garton, FC, Grarup, N, Oskolkov, N, Thalamuthu, A, Mangino, M, Liu, J, Demirkan, A, Lek, M, Xu, L, Wang, G, Oldmeadow, C, Gaulton, KJ, Lotta, LA, Miyamoto-Mikami, E, Rivas, MA, White, T, Loh, P-R, Aadahl, M, Amin, N, Attia, JR, Austin, K, Benyamin, B, Brage, S, Cheng, Y-C, Cięszczyk, P, Derave, W, Eriksson, K-F, Eynon, N, Linneberg, A, Lucia, A, Massidda, M, Mitchell, BD, Miyachi, M, Murakami, H, Padmanabhan, S, Pandey, A, Papadimitriou, I, Rajpal, DK, Sale, C, Schnurr, TM, Sessa, F, Shrine, N, Tobin, MD, Varley, I, Wain, LV, Wray, NR, Lindgren, CM, MacArthur, DG, Waterworth, DM, McCarthy, MI, Pedersen, O, Khaw, K-T, Kiel, DP, Oei, L, Zheng, H-F, Forgetta, V, Leong, A, Ahmad, OS, Laurin, C, Mokry, LE, Ross, S, Elks, CE, Bowden, J, Warrington, NM, Murray, A, Ruth, KS, Tsilidis, KK, Medina-Gómez, C, Estrada, K, Bis, JC, Chasman, DI, Demissie, S, Enneman, AW, Hsu, Y-H, Ingvarsson, T, Kähönen, M, Kammerer, C, Lacroix, AZ, Li, G, Liu, C-T, Liu, Y, Lorentzon, M, Mägi, R, Mihailov, E, Milani, L, Moayyeri, A, Nielson, CM, Sham, PC, Siggeirsdotir, K, Sigurdsson, G, Stefansson, K, Trompet, S, Thorleifsson, G, Vandenput, L, van der Velde, N, Viikari, J, Xiao, S-M, Zhao, JH, Evans, DS, Cummings, SR, Cauley, J, Duncan, EL, de Groot, LCPGM, Esko, T, Gudnason, V, Harris, TB, Jackson, RD, Jukema, JW, Ikram, AMA, Karasik, D, Kaptoge, S, Kung, AWC, Lehtimäki, T, Lyytikäinen, L-P, Lips, P, Luben, R, Metspalu, A, van Meurs, JBJ, Minster, RL, Orwoll, E, Oei, E, Psaty, BM, Raitakari, OT, Ralston, SW, Ridker, PM, Robbins, JA, Smith, AV, Styrkarsdottir, U, Tranah, GJ, Thorstensdottir, U, Uitterlinden, AG, Zmuda, J, Zillikens, MC, Ntzani, EE, Evangelou, E, Ioannidis, JPA, Evans, DM, Ohlsson, C, Pitsiladis, Y, Fuku, N, Franks, PW, North, KN, van Duijn, CM, Mather, KA, Hansen, T, Hansson, O, Spector, T, Murabito, JM, Richards, JB, Rivadeneira, F, Langenberg, C, Perry, JRB, Wareham, NJ, Scott, RA
Publikováno v:
Nature communications, vol 8, iss 1
Nature Communications, 8
Nature Communications
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
NATURE COMMUNICATIONS
Nature Communications 8 (2017)
Willems, S M, et al., Grarup, N, Linneberg, A, Schnurr, T M, Pedersen, O, GEFOS Any-Type of Fracture Consortium & Hansen, T 2017, ' Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness ', Nature Communications, vol. 8, 16015 . https://doi.org/10.1038/ncomms16015
Willems, S M, Wright, D J, Day, F R, Trajanoska, K, Joshi, P K, Morris, J A, Matteini, A M, Garton, F C, Grarup, N, Oskolkov, N, Thalamuthu, A, Mangino, M, Liu, J, Demirkan, A, Lek, M, Xu, L, Wang, G, Oldmeadow, C, Gaulton, K J, Lotta, L A, Miyamoto-Mikami, E, Rivas, M A, White, T, Loh, P R, Aadahl, M, Amin, N, Attia, J R, Austin, K, Benyamin, B, Brage, S, Cheng, Y C, Ciȩszczyk, P, Derave, W, Eriksson, K F, Eynon, N, Linneberg, A, Lucia, A, Massidda, M, Mitchell, B D, Miyachi, M, Murakami, H, Padmanabhan, S, Pandey, A, Papadimitriou, I, Rajpal, D K, Sale, C, Schnurr, T M, Sessa, F, Shrine, N, Hansen, T & GEFOS Anytype of Fracture Consortium 2017, ' Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness ', Nature Communications, vol. 8, 16015 . https://doi.org/10.1038/ncomms16015
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Nature Communications, 8:16015. Nature Publishing Group
Willems, S M, Wright, D J, Day, F R, Trajanoska, K, Joshi, P K, Morris, J A, Matteini, A M, Garton, F C, Grarup, N, Oskolkov, N, Thalamuthu, A, Mangino, M, Liu, J, Demirkan, A, Lek, M, Xu, L, Wang, G, Oldmeadow, C, Gaulton, K J, Lotta, L A, Miyamoto-Mikami, E, Rivas, M A, White, T, Loh, P R, Aadahl, M, Amin, N, Attia, J R, Austin, K, Benyamin, B, Brage, S, Cheng, Y C, Ciȩszczyk, P, Derave, W, Eriksson, K F, Eynon, N, Linneberg, A, Lucia, A, Massidda, M, Mitchell, B D, Miyachi, M, Murakami, H, Padmanabhan, S, Pandey, A, Papadimitriou, I, Rajpal, D K, Sale, C, Schnurr, T M, Sessa, F, Shrine, N, Tobin, M D, Varley, I, Wain, L V, Wray, N R, Lindgren, C M, MacArthur, D G, Waterworth, D M, McCarthy, M I, Pedersen, O, Khaw, K T, Kiel, D P, Pitsiladis, Y, Fuku, N, Franks, P W, North, K N, Van Duijn, C M, Mather, K A, Hansen, T, Hansson, O, Spector, T, Murabito, J M, Richards, J B, Rivadeneira, F, Langenberg, C, Perry, J R B, Wareham, N J, Scott, R A, Oei, L, Zheng, H F, Forgetta, V, Leong, A, Ahmad, O S, Laurin, C, Mokry, L E, Ross, S, Elks, C E, Bowden, J, Warrington, N M, Murray, A, Ruth, K S, Tsilidis, K K, Medina-Gómez, C, Estrada, K, Bis, J C, Chasman, D I, Demissie, S, Enneman, A W, Hsu, Y H, Ingvarsson, T, Kähönen, M, Kammerer, C, Lacroix, A Z, Li, G, Liu, C T, Liu, Y, Lorentzon, M, Mägi, R, Mihailov, E, Milani, L, Moayyeri, A, Nielson, C M, Sham, P C, Siggeirsdotir, K, Sigurdsson, G, Stefansson, K, Trompet, S, Thorleifsson, G, Vandenput, L, Van Der Velde, N, Viikari, J, Xiao, S M, Zhao, J H, Evans, D S, Cummings, S R, Cauley, J, Duncan, E L, De Groot, L C P G M, Esko, T, Gudnason, V, Harris, T B, Jackson, R D, Jukema, J W, Ikram, A M A, Karasik, D, Kaptoge, S, Kung, A W C, Lehtimäki, T, Lyytikäinen, L P, Lips, P, Luben, R, Metspalu, A, Van Meurs, J B J, Minster, R L, Orwoll, E, Oei, E, Psaty, B M, Raitakari, O T, Ralston, S W, Ridker, P M, Robbins, J A, Smith, A V, Styrkarsdottir, U, Tranah, G J, Thorstensdottir, U, Uitterlinden, A G, Zmuda, J, Zillikens, M C, Ntzani, E E, Evangelou, E, Ioannidis, J P A, Evans, D M & Ohlsson, C 2017, ' Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness ', Nature Communications, vol. 8, 16015 . https://doi.org/10.1038/ncomms16015
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications, 8
Nature Communications
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
NATURE COMMUNICATIONS
Nature Communications 8 (2017)
Willems, S M, et al., Grarup, N, Linneberg, A, Schnurr, T M, Pedersen, O, GEFOS Any-Type of Fracture Consortium & Hansen, T 2017, ' Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness ', Nature Communications, vol. 8, 16015 . https://doi.org/10.1038/ncomms16015
Willems, S M, Wright, D J, Day, F R, Trajanoska, K, Joshi, P K, Morris, J A, Matteini, A M, Garton, F C, Grarup, N, Oskolkov, N, Thalamuthu, A, Mangino, M, Liu, J, Demirkan, A, Lek, M, Xu, L, Wang, G, Oldmeadow, C, Gaulton, K J, Lotta, L A, Miyamoto-Mikami, E, Rivas, M A, White, T, Loh, P R, Aadahl, M, Amin, N, Attia, J R, Austin, K, Benyamin, B, Brage, S, Cheng, Y C, Ciȩszczyk, P, Derave, W, Eriksson, K F, Eynon, N, Linneberg, A, Lucia, A, Massidda, M, Mitchell, B D, Miyachi, M, Murakami, H, Padmanabhan, S, Pandey, A, Papadimitriou, I, Rajpal, D K, Sale, C, Schnurr, T M, Sessa, F, Shrine, N, Hansen, T & GEFOS Anytype of Fracture Consortium 2017, ' Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness ', Nature Communications, vol. 8, 16015 . https://doi.org/10.1038/ncomms16015
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Nature Communications, 8:16015. Nature Publishing Group
Willems, S M, Wright, D J, Day, F R, Trajanoska, K, Joshi, P K, Morris, J A, Matteini, A M, Garton, F C, Grarup, N, Oskolkov, N, Thalamuthu, A, Mangino, M, Liu, J, Demirkan, A, Lek, M, Xu, L, Wang, G, Oldmeadow, C, Gaulton, K J, Lotta, L A, Miyamoto-Mikami, E, Rivas, M A, White, T, Loh, P R, Aadahl, M, Amin, N, Attia, J R, Austin, K, Benyamin, B, Brage, S, Cheng, Y C, Ciȩszczyk, P, Derave, W, Eriksson, K F, Eynon, N, Linneberg, A, Lucia, A, Massidda, M, Mitchell, B D, Miyachi, M, Murakami, H, Padmanabhan, S, Pandey, A, Papadimitriou, I, Rajpal, D K, Sale, C, Schnurr, T M, Sessa, F, Shrine, N, Tobin, M D, Varley, I, Wain, L V, Wray, N R, Lindgren, C M, MacArthur, D G, Waterworth, D M, McCarthy, M I, Pedersen, O, Khaw, K T, Kiel, D P, Pitsiladis, Y, Fuku, N, Franks, P W, North, K N, Van Duijn, C M, Mather, K A, Hansen, T, Hansson, O, Spector, T, Murabito, J M, Richards, J B, Rivadeneira, F, Langenberg, C, Perry, J R B, Wareham, N J, Scott, R A, Oei, L, Zheng, H F, Forgetta, V, Leong, A, Ahmad, O S, Laurin, C, Mokry, L E, Ross, S, Elks, C E, Bowden, J, Warrington, N M, Murray, A, Ruth, K S, Tsilidis, K K, Medina-Gómez, C, Estrada, K, Bis, J C, Chasman, D I, Demissie, S, Enneman, A W, Hsu, Y H, Ingvarsson, T, Kähönen, M, Kammerer, C, Lacroix, A Z, Li, G, Liu, C T, Liu, Y, Lorentzon, M, Mägi, R, Mihailov, E, Milani, L, Moayyeri, A, Nielson, C M, Sham, P C, Siggeirsdotir, K, Sigurdsson, G, Stefansson, K, Trompet, S, Thorleifsson, G, Vandenput, L, Van Der Velde, N, Viikari, J, Xiao, S M, Zhao, J H, Evans, D S, Cummings, S R, Cauley, J, Duncan, E L, De Groot, L C P G M, Esko, T, Gudnason, V, Harris, T B, Jackson, R D, Jukema, J W, Ikram, A M A, Karasik, D, Kaptoge, S, Kung, A W C, Lehtimäki, T, Lyytikäinen, L P, Lips, P, Luben, R, Metspalu, A, Van Meurs, J B J, Minster, R L, Orwoll, E, Oei, E, Psaty, B M, Raitakari, O T, Ralston, S W, Ridker, P M, Robbins, J A, Smith, A V, Styrkarsdottir, U, Tranah, G J, Thorstensdottir, U, Uitterlinden, A G, Zmuda, J, Zillikens, M C, Ntzani, E E, Evangelou, E, Ioannidis, J P A, Evans, D M & Ohlsson, C 2017, ' Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness ', Nature Communications, vol. 8, 16015 . https://doi.org/10.1038/ncomms16015
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Hand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause mortality. To investigate the genetic determinants of variation in grip strength, we perform a large-scale genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcc1f9f3f763e8acce552d31dcbf930
https://hdl.handle.net/11541.2/130359
https://hdl.handle.net/11541.2/130359
Autor:
Otowa, T, Hek, Karin, Lee, Max, Byrne, EM, Mirza, Saira, Nivard, MG, Bigdeli, T, Aggen, SH, Adkins, D, Wolen, A, Fanous, A, Keller, MC, Castelao, E, Kutalik, Z, Auwera, SVD, Homuth, G, Nauck, M, Teumer, A, Milaneschi, Y, Hottenga, JJ, Direk, Nese, Hofman, Bert, Uitterlinden, André, Mulder, Niels, Henders, AK, Medland, SE, Gordon, S, Heath, AC, Madden, PAF, Pergadia, ML, van der Most, PJ, Nolte, IM, Oort, Floor, Hartman, CA, Oldehinkel, AJ, Preisig, M, Grabe, HJ, Middeldorp, CM, Penninx, BWJH, Boomsma, D, Martin, NG, Montgomery, G, Maher, BS, van den Oord, EJ, Wray, NR, Tiemeier, Henning, Hettema, JM
Publikováno v:
Molecular Psychiatry, 21(10), 1485-1485. Nature Publishing Group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::8e8c8bb3dac94903eedb47c1cf71ca04
https://pure.eur.nl/en/publications/568f86fc-a100-429d-876b-98aaadeddaa3
https://pure.eur.nl/en/publications/568f86fc-a100-429d-876b-98aaadeddaa3