DNA sensor-associated type I interferon signaling is increased in ulcerative colitis and induces JAK-dependent inflammatory cell death in colonic organoids.

Autor: Flood P; APC Microbiome Ireland, University College Cork, Cork, Ireland., Fanning A; APC Microbiome Ireland, University College Cork, Cork, Ireland., Woznicki JA; APC Microbiome Ireland, University College Cork, Cork, Ireland., Crowley T; APC Microbiome Ireland, University College Cork, Cork, Ireland., Christopher A; APC Microbiome Ireland, University College Cork, Cork, Ireland., Vaccaro A; APC Microbiome Ireland, University College Cork, Cork, Ireland., Houston A; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Medicine, University College Cork, Cork, Ireland., McSweeney S; APC Microbiome Ireland, University College Cork, Cork, Ireland., Ross S; APC Microbiome Ireland, University College Cork, Cork, Ireland., Hogan A; APC Microbiome Ireland, University College Cork, Cork, Ireland., Brint E; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Pathology, Cork University Hospital, University College Cork, Clinical Sciences Building, Cork, Ireland., Skowyra A; APC Microbiome Ireland, University College Cork, Cork, Ireland., Bustamante M; APC Microbiome Ireland, University College Cork, Cork, Ireland., Ambrose M; APC Microbiome Ireland, University College Cork, Cork, Ireland., Moloney G; APC Microbiome Ireland, University College Cork, Cork, Ireland., MacSharry J; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland.; School of Medicine, University College Cork, Cork, Ireland., Hammarström ML; Section of Infection and Immunology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden., Hurley M; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Medicine, University College Cork, Cork, Ireland., Fitzgibbons C; APC Microbiome Ireland, University College Cork, Cork, Ireland., Quigley EMM; APC Microbiome Ireland, University College Cork, Cork, Ireland., Shanahan F; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Medicine, University College Cork, Cork, Ireland., Zulquernain SA; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Medicine, University College Cork, Cork, Ireland., McCarthy J; Department of Gastroenterology, Mercy University Hospital, Cork, Ireland., Dodson GS; Second Genome, Brisbane, California., Dabbagh K; Second Genome, Brisbane, California., McRae BL; Immunology Discovery, Abbvie Bioresearch Center, Worcester, Massachusetts., Melgar S; APC Microbiome Ireland, University College Cork, Cork, Ireland., Nally K; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.

Publikováno v: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2022 Nov 01; Vol. 323 (5), pp. G439-G460. Date of Electronic Publication: 2022 Sep 27.

Bifidobacterium breve Exopolysaccharide Blocks Dendritic Cell Maturation and Activation of CD4 ⁺ T Cells.

Autor: Hickey A; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland., Stamou P; APC Microbiome Ireland, University College Cork, Cork, Ireland., Udayan S; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland., Ramón-Vázquez A; APC Microbiome Ireland, University College Cork, Cork, Ireland., Esteban-Torres M; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Bottacini F; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Woznicki JA; APC Microbiome Ireland, University College Cork, Cork, Ireland., Hughes O; Luminex Corporation, Austin, TX, United States., Melgar S; APC Microbiome Ireland, University College Cork, Cork, Ireland., Ventura M; Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy., Van Sinderen D; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Rossini V; APC Microbiome Ireland, University College Cork, Cork, Ireland., Nally K; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2021 Jun 16; Vol. 12, pp. 653587. Date of Electronic Publication: 2021 Jun 16 (Print Publication: 2021).