Sharks give a handle to potent anti-tumor multiparatopic antibodies inducing membrane depletion of PD-L1.

Autor: Wozniak-Knopp G; Institute of Molecular Biotechnology, Department of Biotechnology, BOKU University, Vienna, Austria; acib GmbH (Austrian Centre of Industrial Biotechnology), Graz, Austria. Electronic address: gordana.wozniak@boku.ac.at., Natale V; Institute of Molecular Biotechnology, Department of Biotechnology, BOKU University, Vienna, Austria; acib GmbH (Austrian Centre of Industrial Biotechnology), Graz, Austria.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2024 May 16; Vol. 31 (5), pp. 833-834.

Easy assessment of the avidity of polyclonal allergen-specific serum antibodies.

Autor: Strobl MR; Center for Pathophysiology, Infectiology and Immunology, Institute of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria., Demir H; Center for Pathophysiology, Infectiology and Immunology, Institute of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria., Wozniak-Knopp G; Department of Biotechnology, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria., Wangorsch A; Molecular Allergology, Paul-Ehrlich-Institute, Langen, Germany., Rüker F; Department of Biotechnology, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria., Bohle B; Center for Pathophysiology, Infectiology and Immunology, Institute of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2024 Apr; Vol. 54 (4), pp. 278-285. Date of Electronic Publication: 2024 Jan 06.

Development of a Cytotoxic Antibody-Drug Conjugate Targeting Membrane Immunoglobulin E-Positive Cells.

Autor: Rodak A; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences (BOKU), Muthgasse 18, 1190 Vienna, Austria., Stadlbauer K; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences (BOKU), Muthgasse 18, 1190 Vienna, Austria., Bobbili MR; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences (BOKU), Muthgasse 18, 1190 Vienna, Austria.; Ludwig Boltzmann Institute for Traumatology, The Research Centre in Cooperation with AUVA, Donaueschingenstraße 13, 1200 Vienna, Austria., Smrzka O; Ablevia Biotech GmbH, Maria Jacobi Gasse 1, 1030 Vienna, Austria., Rüker F; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences (BOKU), Muthgasse 18, 1190 Vienna, Austria., Wozniak Knopp G; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences (BOKU), Muthgasse 18, 1190 Vienna, Austria.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 08; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 08.

Trispecific antibodies produced from mAb ² pairs by controlled Fab-arm exchange.

Autor: Natale V; Department of Biotechnology, Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Muthgasse 18, A-1190 Vienna, Austria., Stadlmayr G; Department of Biotechnology, Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Muthgasse 18, A-1190 Vienna, Austria., Benedetti F; Department of Biotechnology, Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Muthgasse 18, A-1190 Vienna, Austria., Stadlbauer K; Department of Biotechnology, Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Muthgasse 18, A-1190 Vienna, Austria., Rüker F; Department of Biotechnology, Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Muthgasse 18, A-1190 Vienna, Austria., Wozniak-Knopp G; Department of Biotechnology, Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Muthgasse 18, A-1190 Vienna, Austria.

Publikováno v: Biological chemistry [Biol Chem] 2022 Jan 31; Vol. 403 (5-6), pp. 509-523. Date of Electronic Publication: 2022 Jan 31 (Print Publication: 2022).

Construction of Yeast Display Libraries for Selection of Antigen-Binding Variants of Large Extracellular Loop of CD81, a Major Surface Marker Protein of Extracellular Vesicles.

Autor: Vogt S; acib GmbH (Austrian Centre of Industrial Biotechnology), Graz, Austria.; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria., Stadlmayr G; Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria., Stadlbauer K; Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria., Stracke F; Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria., Bobbili MR; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria.; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the AUVA Research Center, Vienna, Austria., Grillari J; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria.; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the AUVA Research Center, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria., Rüker F; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria., Wozniak-Knopp G; Christian Doppler Laboratory for Innovative Immunotherapeutics, Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna (BOKU), Vienna, Austria. gordana.wozniak@boku.ac.at.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2491, pp. 561-592.