Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

Autor: Reinhard Büttner, Päivi Peltomäki, Monique E. van Leerdam, Alexandra M. J. Langers, Markus Loeffler, Wouter T. de Vos tot Nederveen Cappel, Robert Hüneburg, Christoph Engel, Deepak Vangala, Stefan Aretz, Christian P. Strassburg, Laura Renkonen-Sinisalo, Albrecht Stenzinger, Volker Endris, Paul C. van de Meeberg, Maarten A J M Jacobs, Toni T. Seppälä, Hendrik Bläker, Anna Lepistö, Aysel Ahadova, Elke Holinski-Feder, Nils Rahner, Jukka-Pekka Mecklin, Monika Morak, Mariëtte C.A. van Kouwen, Matthias Kloor, Verena Steinke-Lange, Magnus von Knebel Doeberitz, Marie Louise Verhulst, Karolin Bucksch, Gabriela Möslein, Jürgen Weitz, Hans F. A. Vasen, Stefanie Holzapfel, Jan J. Koornstra, Silke Zachariae, Marloes Bigirwamungu-Bargeman, Karsten Schulmann, Kirsi Pylvänäinen, Juda Vecht

Publikováno v: Engel, C, Ahadova, A, Seppälä, T T, Aretz, S, Bigirwamungu-Bargeman, M, Bläker, H, Bucksch, K, Büttner, R, de Vos tot Nederveen Cappel, W T, Endris, V, Holinski-Feder, E, Holzapfel, S, Hüneburg, R, Jacobs, M A J M, Koornstra, J J, Langers, A M, Lepistö, A, Morak, M, Möslein, G, Peltomäki, P, Pylvänäinen, K, Rahner, N, Renkonen-Sinisalo, L, Schulmann, K, Steinke-Lange, V, Stenzinger, A, Strassburg, C P, van de Meeberg, P C, van Kouwen, M, van Leerdam, M, Vangala, D B, Vecht, J, Verhulst, M L, von Knebel Doeberitz, M, Weitz, J, Zachariae, S, Loeffler, M, Mecklin, J P, Kloor, M, Vasen, H F, German HNPCC Consortium, the Dutch Lynch Syndrome Collaborative Group & Finnish Lynch Syndrome Registry 2020, ' Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome ', Gastroenterology, vol. 158, no. 5, pp. 1326-1333 . https://doi.org/10.1053/j.gastro.2019.12.032
Gastroenterology, 158(5), 1326-1333. W B SAUNDERS CO-ELSEVIER INC
Gastroenterology, 158, 5, pp. 1326-1333
Gastroenterology, 158, 1326-1333
Gastroenterology, 158(5), 1326-1333. W.B. Saunders Ltd

Contains fulltext : 220040.pdf (Publisher’s version ) (Closed access) BACKGROUND & AIMS: Lynch syndrome is caused by variants in DNA mismatch repair (MMR) genes and associated with an increased risk of colorectal cancer (CRC). In patients with Lync

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https://research.vumc.nl/en/publications/19a6d3f9-6a91-4d08-a678-91d7b8485e29