Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Wouter Peelaerts"'
Autor:
Emmanuel Quansah, Wouter Peelaerts, J. William Langston, David K. Simon, Jerry Colca, Patrik Brundin
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-12 (2018)
Abstract Several molecular pathways are currently being targeted in attempts to develop disease-modifying therapies to slow down neurodegeneration in Parkinson’s disease. Failure of cellular energy metabolism has long been implicated in sporadic Pa
Externí odkaz:
https://doaj.org/article/fc7a398e8b604c5796d6bdee678406c9
Autor:
Wouter Peelaerts, Liza Bergkvist, Sonia George, Michaela Johnson, Lindsay Meyerdirk, Emily Schulz, Jennifer A. Steiner, Zachary Madaj, Jiyan Ma, Katelyn Becker, K. Peter R. Nilsson, Jerry R. Colca, Patrik Brundin
Publikováno v:
Free Neuropathology, Vol 1, Pp 33-33 (2020)
Epidemiological studies suggest a link between type-2 diabetes and Parkinson’s disease (PD) risk. Treatment of type-2 diabetes with insulin sensitizing drugs lowers the risk of PD. We previously showed that the insulin sensitizing drug, MSDC-0160,
Externí odkaz:
https://doaj.org/article/1a77645d12c548a3ba5d9c06a4db6d52
Autor:
Wouter Peelaerts
Publikováno v:
Advances in Clinical Neuroscience & Rehabilitation, Vol , Iss (2016)
Recent and exciting developments are providing new clues as to how different synucleinopathies such as Parkinson’s Disease (PD), Multiple System Atrophy (MSA) and neocortical Lewy Body Dementia (LBD) might originate.
Externí odkaz:
https://doaj.org/article/b1844700ad3c43bca65c68c6f07e4b48
Autor:
Wouter Peelaerts, Gabriela Mercado, Sonia George, Marie Villumsen, Alysa Kasen, Miguel Aguileta, Christian Linstow, Alexandra B. Sutter, Emily Kuhn, Lucas Stetzik, Rachel Sheridan, Liza Bergkvist, Lindsay Meyerdirk, Allison Lindqvist, Martha L. Escobar Gavis, Chris Van den Haute, Scott J. Hultgren, Veerle Baekelandt, J. Andrew Pospisilik, Tomasz Brudek, Susana Aznar, Jennifer A. Steiner, Michael X. Henderson, Lena Brundin, Magdalena I. Ivanova, Tom J. Hannan, Patrik Brundin
Publikováno v:
Acta Neuropathologica. 145:541-559
Symptoms in the urogenital organs are common in multiple system atrophy (MSA), also in the years preceding the MSA diagnosis. It is unknown how MSA is triggered and these observations in prodromal MSA led us to hypothesize that synucleinopathy could
Autor:
Wouter Peelaerts, Veerle Baekelandt
Publikováno v:
Neurotherapeutics. 20:67-82
Autor:
Sonia George, Wouter Peelaerts, Amanda R. Burmeister, J. Andrew Pospisilik, Katelyn Becker, Emily Schulz, Jennifer A. Steiner, Rachael Sheridan, Lena Brundin, Viviane Labrie, Trevor A. Tyson, Nolwen L. Rey, Patrik Brundin, Jiyan Ma, Christian Ulrich von Linstow, Lindsay Meyerdirk, Martha L. Escobar Galvis
Publikováno v:
J Parkinsons Dis
BACKGROUND: α-Synuclein (α-syn) is the predominant protein in Lewy-body inclusions, which are pathological hallmarks of α-synucleinopathies, such as Parkinson's disease (PD) and multiple system atrophy (MSA). Other hallmarks include activation of
Autor:
Teresa Torre-Muruzabal, Anke Van der Perren, Audrey Coens, Géraldine Gelders, Anna Barber Janer, Sara Camacho-Garcia, Therése Klingstedt, Peter Nilsson, Nadia Stefanova, Ronald Melki, Veerle Baekelandt, Wouter Peelaerts
Multiple system atrophy is a progressive neurodegenerative disease with prominent autonomic and motor features. During early stages, different subtypes of the disease are distinguished by their predominant parkinsonian or cerebellar symptoms, reflect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f110be9240c11a501274ecd75729ba
https://lirias.kuleuven.be/handle/20.500.12942/690671
https://lirias.kuleuven.be/handle/20.500.12942/690671
Publikováno v:
Journal of Neural Transmission
Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA), and dysautonomia with cerebellar ataxia or parkinsonian motor features. Isolated autonom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e2bc048c5e1ff3c7c1396d35c89a35
https://lirias.kuleuven.be/handle/20.500.12942/689108
https://lirias.kuleuven.be/handle/20.500.12942/689108
Autor:
Veerle Baekelandt, Chris Van den Haute, Anna Barber Janer, Wouter Peelaerts, Jennifer A. Steiner, Filipa Brito, Patrik Brundin
Publikováno v:
Human gene therapy. 32(11-12)
Several neurodegenerative disorders are characterized by oligodendroglial pathology and myelin loss. Oligodendrogliopathies are a group of rare diseases for which there currently is no therapy. Gene delivery through viral vectors to oligodendrocytes
Autor:
Chris Van den Haute, Géraldine Gelders, Anke Van der Perren, Steve M. Gentleman, Alexis Fenyi, Veerle Baekelandt, Wouter Peelaerts, Filipa De Brito, Ronald Melki, Luc Bousset
Publikováno v:
Acta Neuropathologica
Acta Neuropathologica, 2020, ⟨10.1007/s00401-020-02157-3⟩
Acta Neuropathologica, Springer Verlag, 2020, ⟨10.1007/s00401-020-02157-3⟩
Acta Neuropathologica, 2020, ⟨10.1007/s00401-020-02157-3⟩
Acta Neuropathologica, Springer Verlag, 2020, ⟨10.1007/s00401-020-02157-3⟩
Synucleinopathies, such as Parkinson's disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), are defined by the presence of α-synuclein (αSYN) aggregates throughout the nervous system but diverge from one another with re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3f0c5e1de94a6f7f98b39cd567d86
https://cea.hal.science/cea-02561795
https://cea.hal.science/cea-02561795