Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wouter P C Boon"'
Autor:
Dirk R M Lukkien, Sima Ipakchian Askari, Nathalie E Stolwijk, Bob M Hofstede, Henk Herman Nap, Wouter P C Boon, Alexander Peine, Ellen H M Moors, Mirella M N Minkman
Publikováno v:
JMIR Human Factors, Vol 11, p e55961 (2024)
BackgroundEmerging technologies such as artificial intelligence (AI) require an early-stage assessment of potential societal and ethical implications to increase their acceptability, desirability, and sustainability. This paper explores and compares
Externí odkaz:
https://doaj.org/article/14b15a2690eb461a95a68fc4b8eb3f00
Autor:
Freek de Haan, Oladimeji Akeem Bolarinwa, Rosemonde Guissou, Fatoumata Tou, Paulina Tindana, Wouter P C Boon, Ellen H M Moors, Phaik Yeong Cheah, Mehul Dhorda, Arjen M Dondorp, Jean Bosco Ouedraogo, Olugbenga A Mokuolu, Chanaki Amaratunga
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256567 (2021)
IntroductionTriple artemisinin-based combination therapies (TACTs) are being developed as a response to artemisinin and partner drug resistance in the treatment of falciparum malaria in Southeast Asia. In African countries, where current artemisinin-
Externí odkaz:
https://doaj.org/article/0b7960eec00543d4ad1eae88bff71480
Autor:
Guilherme S Ferreira, Désirée H Veening-Griffioen, Wouter P C Boon, Ellen H M Moors, Christine C Gispen-de Wied, Huub Schellekens, Peter J K van Meer
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218014 (2019)
IntroductionPoor translation of efficacy data derived from animal models can lead to clinical trials unlikely to benefit patients-or even put them at risk-and is a potential contributor to costly and unnecessary attrition in drug development.Objectiv
Externí odkaz:
https://doaj.org/article/0f14ca084e9b487cb8a1f7e01b4a38f6
Autor:
Guilherme S Ferreira, Désirée H Veening-Griffioen, Wouter P C Boon, Ellen H M Moors, Christine C Gispen-de Wied, Huub Schellekens, Peter J K van Meer
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220325 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0218014.].
Externí odkaz:
https://doaj.org/article/4a9a1b7212f24fd09f77e8357dbb8bd4
Autor:
Guilherme S. Ferreira, Désirée H. Veening-Griffioen, Wouter P. C. Boon, Ellen H. M. Moors, Peter J. K. van Meer
Publikováno v:
Animals, Vol 10, Iss 7, p 1199 (2020)
Reports of a reproducibility crisis combined with a high attrition rate in the pharmaceutical industry have put animal research increasingly under scrutiny in the past decade. Many researchers and the general public now question whether there is stil
Externí odkaz:
https://doaj.org/article/786ec96520b24d25bd7663606e9e8672
Publikováno v:
Expert review of molecular diagnostics. 22(5)
The In Vitro Diagnostics Regulation 2017/746 (IVDR) coming into force from May 2022, creates the first European regulatory recognition for biomarker tests linked to medicinal products, so-called companion diagnostics (CDx). Since the introduction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::522de1bce39850caf74a644db378052b
https://pubmed.ncbi.nlm.nih.gov/35673983
https://pubmed.ncbi.nlm.nih.gov/35673983
Autor:
Van Anh Thi Cao, Thieu Quang Nguyen, Duong Le Quyen, Wouter P. C. Boon, Ellen H. M. Moors, Arjen M. Dondorp, Freek de Haan, Chanaki Amaratunga
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-8 (2023)
Abstract Background This study investigates the processes regarding changing malaria treatment policies in Vietnam. Moreover, it explores the feasibility of introducing triple artemisinin-based combination therapy (TACT) in Vietnam to support the nat
Externí odkaz:
https://doaj.org/article/2d66ede009644e0a8a8fb62360d26d0d
Autor:
Rosemonde M. Guissou, Chanaki Amaratunga, Freek de Haan, Fatoumata Tou, Phaik Yeong Cheah, R. Serge Yerbanga, Ellen H. M. Moors, Mehul Dhorda, Paulina Tindana, Wouter P. C. Boon, Arjen M. Dondorp, Jean Bosco Ouédraogo
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-14 (2023)
Abstract Background Widespread artemisinin resistance in Africa could be catastrophic when drawing parallels with the failure of chloroquine in the 1970s and 1980s. This article explores the role of anti-malarial market characteristics in the emergen
Externí odkaz:
https://doaj.org/article/a2100af6ffaa48bcbff4f59add2c82ee
Autor:
Freek de Haan, Chanaki Amaratunga, Van Anh Cao Thi, Long Heng Orng, Manithong Vonglokham, Thieu Nguyen Quang, Dysoley Lek, Wouter P. C. Boon, Arjen M. Dondorp, Ellen H. M. Moors
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background This is a qualitative study to identify implementation challenges for deploying triple artemisinin-based combination therapy (TACT) in the Greater Mekong Subregion (GMS) of Southeast Asia and to explore strategies to overcome thes
Externí odkaz:
https://doaj.org/article/526225ade12843e383855c84cd96d85c
Autor:
Guilherme S. Ferreira, Francis M. Dijkstra, Désirée H. Veening-Griffioen, Wouter P. C. Boon, Huub Schellekens, Ellen H. M. Moors, Peter J. K. van Meer, Frederik E. Stuurman, Joop M. A. van Gerven
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The primary purpose of this study was to assess the translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system (CNS) active drugs. As a part of this, IBs were reviewed on re
Externí odkaz:
https://doaj.org/article/969744b409794e0e8e65ec07d7ce391d