Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Wouter Laroy"'
Autor:
Wouter, Laroy, Paul, Ladestein
Publikováno v:
Biomarkers in Medicine. 9:85-88
MyCartis NV, a new player on the clinical and translational research market, aims at revolutionizing current healthcare systems. These are mostly based on treating the diseased rather than on caring better and longer for the healthy. The ‘one size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e238f78f7800792bb37a6c56a9e0b7a8
https://doi.org/10.2217/bmm.14.109
https://doi.org/10.2217/bmm.14.109
Autor:
Grégoire Thomas, Thenral Socrates, Christian Mueller, Griet Vanpoucke, Wouter Laroy, Mihael Potocki, Tobias Breidthardt, Tamina Mosimann, Ronny Ziller, Alexandre Mebazaa, Beatrice Drexler, Koen Kas, Piet Moerman
Publikováno v:
Clinical Science. 123:557-566
The risk stratification in patients presenting with acute dyspnoea remains a challenge. We therefore conducted a prospective, observational cohort study enrolling 292 patients presenting to the emergency department with acute dyspnoea. A proteomic ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee70a370cac9b05ec7257836baa47677
https://doi.org/10.1042/cs20120058
https://doi.org/10.1042/cs20120058
Autor:
Jan Wuyts, Robin Tuytten, Christian Mueller, Huw Davies, Jean-Marie Launay, Piet Moerman, Alexandre Mebazaa, Brice Lortat-Jacob, Jozef Bartunek, Griet Vanpoucke, Wouter Laroy, Koen De Cremer, Corinne Collet, Filip D'hondt, Damien Logeart, Caroline Vanhaute, Jane-Lise Samuel, Marc Vanderheyden, Grégoire Thomas, Elisabeth Verschuere, Natalie Van Landuyt, James L. Januzzi, Koen Kas, Miguel Tavares, Katleen Verleysen, Alain Cohen-Solal, Lies Vanneste
Publikováno v:
European Heart Journal. 33:2317-2324
Aims Biochemical marker testing has improved the evaluation and management of patients with cardiovascular diseases over the past decade. Natriuretic peptides (NPs), used in clinical practice to assess cardiac dysfunction, exhibit many limitations, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e417ae773900371d78c3e8393102b4
https://doi.org/10.1093/eurheartj/ehs162
https://doi.org/10.1093/eurheartj/ehs162
Autor:
Sherry A. Hudson, Leonardo Nimrichter, Wouter Laroy, Ronald L. Schnaar, Bruce S. Bochner, Konstantinos Konstantopoulos, Robert J. Cotter, Michael Tiemeyer, Monica M. Burdick, Kazuhiro Aoki, Mark A. Fierro, Christopher E. Von Seggern
Publikováno v:
Blood. 112:3744-3752
Selectins on activated vascular endothelium mediate inflammation by binding to complementary carbohydrates on circulating neutrophils. The human neutrophil receptor for E-selectin has not been established. We report here that sialylated glycosphingol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff39135fde3e614423ba5dd4a3b03b3
https://doi.org/10.1182/blood-2008-04-149641
https://doi.org/10.1182/blood-2008-04-149641
Autor:
Vivianne I. Otto, Wouter Laroy, Matthias J.T. Meyer, Nico Callewaert, Christian Tränkle, Thomas Schürpf, Richard D. Cummings
Publikováno v:
Open Glycoscience. 1:40-51
Soluble intercellular adhesion molecule-1 (sICAM-1) is elevated in the cerebrospinal fluid of patients with se- vere brain trauma and mouse sICAM-1 induces the production of macrophage inflammatory protein-2 (MIP-2) in mouse astrocytes. The productio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3486fd9abf410a82adfb2ea8e7ebac5
https://doi.org/10.2174/1875398100801010040
https://doi.org/10.2174/1875398100801010040
Publikováno v:
Biogerontology. 9:351-356
Most secreted proteins produced by the human body are modified by glycosylation. It is well known that the oligosaccharides (glycans) of glycoproteins are important for initiation of various cellular recognition signals that are essential for the mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7644faffe884333766b8a1b181b00a8
https://doi.org/10.1007/s10522-008-9140-z
https://doi.org/10.1007/s10522-008-9140-z
Autor:
Claude Libert, Wouter Laroy, Cuiying Chen, Chunfang Gao, Roland Contreras, Xue-En Liu, Valerie Vanhooren, Liesbeth Desmyter, Nico Callewaert, Hui Zhuang, Ling Wang, Sylviane Dewaele
Publikováno v:
Hepatology. 46:1426-1435
We evaluated the use of blood serum N-glycan fingerprinting as a tool for the diagnosis of hepatocellular carcinoma (HCC) in patients with cirrhosis induced by hepatitis B virus (HBV). A group of 450 HBV-infected patients with liver fibrosis or cirrh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61a04e9ffe783963d3c273b6964bc66
https://doi.org/10.1002/hep.21855
https://doi.org/10.1002/hep.21855
Autor:
Roland Hetzer, Anja Haase-Fielitz, Michael Haase, Siegfried Kropf, Rinaldo Bellomo, Griet Thomas, Christian Albert, Gregoire Vanpoucke, Wouter Laroy, Hermann Kuppe, Katleen Verleysen
Publikováno v:
Biomarkers in medicine. 8(10)
Aim: To describe the prognostic value of three novel biomarkers for acute adverse kidney events compared with routine biological markers. Material & methods: We used high-end MS to quantify biomarkers predictive of acute kidney injury (AKI) and major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e78e38b00cf6af66d1631053b4e06f
https://pubmed.ncbi.nlm.nih.gov/25525981
https://pubmed.ncbi.nlm.nih.gov/25525981
Autor:
Roland Contreras, Myron R. Szewczuk, Wouter Laroy, Kristof De Vusser, Gregory M. Ross, Susan O. Meakin, Alicja Woronowicz
Publikováno v:
Glycobiology. 14:987-998
Trypanosome trans-sialidase (TS) is a sialic acid-transferring enzyme that hydrolyzes alpha2,3-linked sialic acids and transfers them to acceptor molecules. Here we show that a highly purified recombinant TS derived from T. cruzi parasites targets Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be27bad6d8421a0e344cb6cb237c2c22
https://doi.org/10.1093/glycob/cwh123
https://doi.org/10.1093/glycob/cwh123
Autor:
Hans Van Vlierberghe, Nico Callewaert, Annelies Van Hecke, Wouter Laroy, Roland Contreras, Joris R. Delanghe
Publikováno v:
Nature Medicine. 10:429-434
We applied our 'clinical glycomics' technology, based on DNA sequencer/fragment analyzers, to generate profiles of serum protein N-glycans of liver disease patients. This technology yielded a biomarker that distinguished compensated cirrhotic from no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00e5da758d13fc964e8759ab8e06bb1
https://doi.org/10.1038/nm1006
https://doi.org/10.1038/nm1006