Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wouter J. Eijgelaar"'
Publikováno v:
Genomics Data, Vol 6, Iss C, Pp 136-138 (2015)
The formation of foamy macrophages by sequestering extracellular modified lipids is a key event in atherosclerosis. However, there is controversy about the effects of lipid loading on macrophage phenotype, with in vitro evidence suggesting either pro
Externí odkaz:
https://doaj.org/article/b4e71bfde59847898ed727e46703dd2d
Autor:
Barend Mees, Judith C. Sluimer, Mat J.A.P. Daemen, Cornelis J J M Sikkink, Peter Juhasz, Marco Manca, Martina Kutmon, Olivia J Waring, Kim van Kuijk, Ljubica Perisic Matic, Pieter Goossens, Marion J.J. Gijbels, Ulf Hedin, Erik A.L. Biessen, Chris T. Evelo, Evgueni Smirnov, Gregorio E Fazzi, Wouter J. Eijgelaar, Han Jin, Joël Karel
Publikováno v:
Clinical and translational medicine 11(6), e458 (2021). doi:10.1002/ctm2.458
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Clinical and Translational Medicine, 11(6):e458. Springer Verlag
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Clinical and Translational Medicine, 11(6):e458. Springer Verlag
Clinical and Translational Medicine
Background While single‐omics analyses on human atherosclerotic plaque have been very useful to map stage‐ or disease‐related differences in expression, they only partly capture the array of changes in this tissue and suffer from scale‐intrin
Autor:
Pieter Goossens, Marion J.J. Gijbels, Christian Weber, Monique N. Vergouwe, Ulrich Kalinke, Esther Lutgens, Alma Zernecke, Wim A. Buurman, Linda Beckers, Ingeborg van der Made, Wouter J. Eijgelaar, Menno P.J. de Winther, Mat J.A.P. Daemen, Joris Vanderlocht
Publikováno v:
Cell metabolism, 12(2), 142-153. Cell Press
Cell Metabolism, 12(2), 142-153. Cell Press
Cell Metabolism, 12(2), 142-153. Cell Press
Inflammatory cytokines are well-recognized mediators of atherosclerosis. Depending on the pathological context, type I interferons (IFNs; IFNalpha and IFNbeta) exert either pro- or anti-inflammatory immune functions, but their exact role in atherogen
Autor:
A.P.J.J. Bijnens, Wouter J. Eijgelaar, Anton J.G. Horrevoets, Wim Verhaegh, Mat J.A.P. Daemen
Publikováno v:
Physiological Genomics, 41(3), 212-223. American Physiological Society
Physiological genomics, 41(3), 212-223. American Physiological Society
Eijgelaar, W J, Horrevoets, A J G, Bijnens, A P J J, Daemen, M J A P & Verhaegh, W F J 2010, ' Equivalence testing in microarray analysis: similarities in the transcriptome of human atherosclerotic and nonatherosclerotic macrophages ', Physiological Genomics, vol. 41, no. 3, pp. 212-223 . https://doi.org/10.1152/physiolgenomics.00193.2009
Physiological genomics, 41(3), 212-223. American Physiological Society
Eijgelaar, W J, Horrevoets, A J G, Bijnens, A P J J, Daemen, M J A P & Verhaegh, W F J 2010, ' Equivalence testing in microarray analysis: similarities in the transcriptome of human atherosclerotic and nonatherosclerotic macrophages ', Physiological Genomics, vol. 41, no. 3, pp. 212-223 . https://doi.org/10.1152/physiolgenomics.00193.2009
Eijgelaar WJ, Horrevoets AJ, Bijnens AP, Daemen MJ, Verhaegh WF. Equivalence testing in microarray analysis: similarities in the transcriptome of human atherosclerotic and nonatherosclerotic macrophages. Physiol Genomics 41: 212-223, 2010. First publ
Publikováno v:
Thrombosis and haemostasis, 102(2), 231-239. Schattauer GmbH
SummaryThe term ‘vulnerable plaque’ is used to refer to the lesions that are prone to rupture and may cause life-threatening events like acute coronary syndrome or stroke.The study of the vulnerable plaque phenotype and its detection has attracte
Publikováno v:
Thrombosis and Haemostasis. 102:206-214
SummaryDisrupting the CD40-CD40L co-stimulatory pathway reduces atherosclerosis and induces a stable atherosclerotic plaque phenotype that is low in inflammation and high in fibrosis. Therefore, inhibition of the CD40-CD40L pathway is an attractive t
Publikováno v:
Genomics Data
Genomics Data, Vol 6, Iss C, Pp 136-138 (2015)
Genomics data, 6, 136-138. Elsevier Inc.
Thomas, A C, Eigelaar, W, Daemen, M & Newby, A C 2015, ' The pro-fibrotic and anti-inflammatory foam cell macrophage paradox ', Genomics Data, vol. 6, pp. 136-138 . https://doi.org/10.1016/j.gdata.2015.08.027
Genomics Data, Vol 6, Iss C, Pp 136-138 (2015)
Genomics data, 6, 136-138. Elsevier Inc.
Thomas, A C, Eigelaar, W, Daemen, M & Newby, A C 2015, ' The pro-fibrotic and anti-inflammatory foam cell macrophage paradox ', Genomics Data, vol. 6, pp. 136-138 . https://doi.org/10.1016/j.gdata.2015.08.027
The formation of foamy macrophages by sequestering extracellular modified lipids is a key event in atherosclerosis. However, there is controversy about the effects of lipid loading on macrophage phenotype, with in vitro evidence suggesting either pro
Publikováno v:
PLoS ONE
PLoS ONE, 10(7). Public Library of Science
PLoS ONE, Vol 10, Iss 7, p e0128163 (2015)
PLoS ONE, 10(7). Public Library of Science
PLoS ONE, Vol 10, Iss 7, p e0128163 (2015)
Formation of foam cell macrophages, which sequester extracellular modified lipids, is a key event in atherosclerosis. How lipid loading affects macrophage phenotype is controversial, with evidence suggesting either pro- or anti-inflammatory consequen
Publikováno v:
van Beijnum, J R, Eijgelaar, W J & Griffioen, A W 2006, ' Towards high-throughput functional target discovery in angiogenesis research ', Trends in Molecular Medicine, vol. 12, no. 1, pp. 44-52 . https://doi.org/10.1016/j.molmed.2005.11.005
Angiogenesis is a hallmark of malignancies and other proliferative diseases, and inhibition of this process is considered to be a promising treatment strategy. Classical gene-expression analyses performed during the past decade have generated vast li
Autor:
Jason L. Johnson, Laura Bevan, Stephen J. White, Mat J.A.P. Daemen, Wouter J. Eijgelaar, Anita C Thomas, Andrew C. Newby, Elaine M Hayes
Publikováno v:
Cardiovascular Research. 103:S133.5-S133
Purpose: Foam cell macrophage (FCM) formation is an early event in atherosclerosis that could contribute to fibrous cap development, although it has also been strongly implicated in cap rupture and thrombus formation. To understand this apparent para