Zobrazeno 1 - 10
of 367
pro vyhledávání: '"Wouter H. Lamers"'
Autor:
Anthony Graham, Jill P. J. M. Hikspoors, Wouter H. Lamers, Robert H. Anderson, Simon D. Bamforth
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The heart and aortic arch arteries in amniotes form a double circulation, taking oxygenated blood from the heart to the body and deoxygenated blood to the lungs. These major vessels are formed in embryonic development from a series of paired and symm
Externí odkaz:
https://doaj.org/article/3e1123e0f96d4112a0030df6476909f6
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Effective first aid on the battlefield is vital to minimize deaths caused by war trauma and improve combat effectiveness. However, it is difficult for junior medical students, which have relatively poor human anatomy knowledge and
Externí odkaz:
https://doaj.org/article/101aea2a6b3a45f9991c078965f960fe
Autor:
Jill P. J. M. Hikspoors, Nutmethee Kruepunga, Greet M. C. Mommen, S. Eleonore Köhler, Robert H. Anderson, Wouter H. Lamers
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-22 (2022)
Hikspoors et al. generate a pictorial account of human embryonic heart development between 3.5 and 8 weeks. This resource provides detailed, interactive 3D anatomical models and quantifies the developmental milestones of key structures in cardiac fun
Externí odkaz:
https://doaj.org/article/34177fba4e4542c481284f0bf87f2a8c
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Asthma is a chronic respiratory condition, with airway hyperresponsiveness (AHR) and inflammation as hallmarks. The hypothesis that the substantially increased expression of arginase 1 in activated macrophages limits the availabil
Externí odkaz:
https://doaj.org/article/ab910cb740604b42a6b9457946b3188e
Autor:
Roy H. E. Cloots, Selvakumari Sankaranarayanan, Matthew E. Poynter, Els Terwindt, Paul van Dijk, Wouter H. Lamers, S. Eleonore Köhler
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-15 (2017)
Abstract Background (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis. We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation
Externí odkaz:
https://doaj.org/article/52c157d7096345e2b9b523d74af472c8
Autor:
Erika M. Palmieri, Alessio Menga, Rosa Martín-Pérez, Annamaria Quinto, Carla Riera-Domingo, Giacoma De Tullio, Douglas C. Hooper, Wouter H. Lamers, Bart Ghesquière, Daniel W. McVicar, Attilio Guarini, Massimiliano Mazzone, Alessandra Castegna
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1654-1666 (2017)
Glutamine-synthetase (GS), the glutamine-synthesizing enzyme from glutamate, controls important events, including the release of inflammatory mediators, mammalian target of rapamycin (mTOR) activation, and autophagy. However, its role in macrophages
Externí odkaz:
https://doaj.org/article/63b0d1fd574d4a29ace0010ebbc852fe
Autor:
Alex J. Bott, Jianliang Shen, Claudia Tonelli, Le Zhan, Nithya Sivaram, Ya-Ping Jiang, Xufen Yu, Vrushank Bhatt, Eric Chiles, Hua Zhong, Sara Maimouni, Weiwei Dai, Stephani Velasquez, Ji-An Pan, Nathiya Muthalagu, Jennifer Morton, Tracy G. Anthony, Hui Feng, Wouter H. Lamers, Daniel J. Murphy, Jessie Yanxiang Guo, Jian Jin, Howard C. Crawford, Lanjing Zhang, Eileen White, Richard Z. Lin, Xiaoyang Su, David A. Tuveson, Wei-Xing Zong
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1287-1298.e6 (2019)
Summary: Glutamine is thought to play an important role in cancer cells by being deaminated via glutaminolysis to α-ketoglutarate (aKG) to fuel the tricarboxylic acid (TCA) cycle. Supporting this notion, aKG supplementation can restore growth/surviv
Externí odkaz:
https://doaj.org/article/86935149469c4359a0a906c3024b9071
Autor:
Wendy Xin, Yevgeniya A. Mironova, Hui Shen, Rosa A.M. Marino, Ari Waisman, Wouter H. Lamers, Dwight E. Bergles, Antonello Bonci
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2262-2271.e5 (2019)
Summary: Glutamate has been implicated in a wide range of brain pathologies and is thought to be metabolized via the astrocyte-specific enzyme glutamine synthetase (GS). We show here that oligodendrocytes, the myelinating glia of the central nervous
Externí odkaz:
https://doaj.org/article/a06ba1c26c6e48aba282f87bd4551c61
Autor:
Robert H Anderson, Jill PJM Hikspoors, Justin T Tretter, Yolanda Mac�as, Diane E Spicer, Wouter H Lamers, Dami�n S�nchez-Quintana, Eduardo Back Sternick
Publikováno v:
Arrhythmia & Electrophysiology Review, Vol 10, Iss 4, Pp 262-272 (2021)
Externí odkaz:
https://doaj.org/article/72c0d5b3ee04401983e78604fd6993ad
Autor:
Anthony Graham, Jill P. J. M. Hikspoors, Robert H. Anderson, Wouter H. Lamers, Simon D. Bamforth
Publikováno v:
Journal of Anatomy.