Tertiary lymphoid structures critical for prognosis in endometrial cancer patients.

Autor: Horeweg N; Department of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands. n.horeweg@lumc.nl., Workel HH; Department of Gynaecologic Oncology, University Medical Center Groningen, Groningen, the Netherlands., Loiero D; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Church DN; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Vermij L; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., Léon-Castillo A; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., Krog RT; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.; Department Surgery, Leiden University Medical Center, Leiden, the Netherlands., de Boer SM; Department of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands., Nout RA; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Powell ME; Department of Clinical Oncology, Barts Health NHS Trust, London, United Kingdom., Mileshkin LR; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., MacKay H; Division of Medical Oncology and Hematology, Sunnybrook Odette Cancer Centre, Toronto, ON, Canada., Leary A; Department of Medical Oncology, Gustave Roussy, Villejuif, France., Singh N; Department of Pathology, Barts Health NHS Trust, London, United Kingdom., Jürgenliemk-Schulz IM; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Smit VTHBM; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., Creutzberg CL; Department of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands., Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Department of Oncology and Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Nijman HW; Department of Gynaecologic Oncology, University Medical Center Groningen, Groningen, the Netherlands., Bosse T; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., de Bruyn M; Department of Gynaecologic Oncology, University Medical Center Groningen, Groningen, the Netherlands.

Publikováno v: Nature communications [Nat Commun] 2022 Mar 16; Vol. 13 (1), pp. 1373. Date of Electronic Publication: 2022 Mar 16.

Prognostic image-based quantification of CD8CD103 T cell subsets in high-grade serous ovarian cancer patients.

Autor: Paijens ST; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Vledder A; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Loiero D; Department of Pathology and Molecular Pathology, University Hospital and University of Zurich, Zurich, Switzerland., Duiker EW; Department of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bart J; Department of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Hendriks AM; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Jalving M; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Workel HH; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Hollema H; Department of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Werner N; Department of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Plat A; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Wisman GBA; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Yigit R; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Arts H; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Kruse AJ; Department of Obstetrics and Gynecology, Isala Hospital Zwolle, Zwolle, The Netherlands., de Lange NM; Department of Obstetrics and Gynecology, Isala Hospital Zwolle, Zwolle, The Netherlands., Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital and University of Zurich, Zurich, Switzerland., de Bruyn M; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Nijman HW; Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Publikováno v: Oncoimmunology [Oncoimmunology] 2021 Jun 06; Vol. 10 (1), pp. 1935104. Date of Electronic Publication: 2021 Jun 06.

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer.

Autor: Workel HH; Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands., van Rooij N; Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands., Plat A; Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands., Spierings DCJ; European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands., Fehrmann RSN; Department of Medical Oncology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands., Nijman HW; Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands., de Bruyn M; Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 May 27; Vol. 21 (11). Date of Electronic Publication: 2020 May 27.

A Transcriptionally Distinct CXCL13 ⁺ CD103 ⁺ CD8 ⁺ T-cell Population Is Associated with B-cell Recruitment and Neoantigen Load in Human Cancer.

Autor: Workel HH; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Lubbers JM; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Arnold R; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Prins TM; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., van der Vlies P; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., de Lange K; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Bosse T; Department of Pathology, Leiden University Medical Center, Leiden University, Leiden, the Netherlands., van Gool IC; Department of Pathology, Leiden University Medical Center, Leiden University, Leiden, the Netherlands., Eggink FA; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Wouters MCA; Trev and Joyce Deeley Research Centre, BC Cancer, Victoria, British Columbia, Canada., Komdeur FL; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., van der Slikke EC; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Creutzberg CL; Department of Radiation Oncology, Leiden University Medical Center, Leiden University, Leiden, the Netherlands., Kol A; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Plat A; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Glaire M; Molecular and Population Genetics Laboratory, The Wellcome Trust Centre for Human Genetics and Oxford Cancer Centre, University of Oxford, Oxford, United Kingdom., Church DN; Molecular and Population Genetics Laboratory, The Wellcome Trust Centre for Human Genetics and Oxford Cancer Centre, University of Oxford, Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust and John Radcliffe Hospital, Oxford, United Kingdom., Nijman HW; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., de Bruyn M; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. m.de.bruyn@umcg.nl.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2019 May; Vol. 7 (5), pp. 784-796. Date of Electronic Publication: 2019 Mar 14.

CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma.

Autor: Workel HH; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Komdeur FL; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Wouters MC; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, The Netherlands., Plat A; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Klip HG; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Eggink FA; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Wisman GB; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Arts HJ; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Oonk MH; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Mourits MJ; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Yigit R; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Versluis M; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Duiker EW; University of Groningen, University Medical Center Groningen, Department of Pathology, The Netherlands., Hollema H; University of Groningen, University Medical Center Groningen, Department of Pathology, The Netherlands., de Bruyn M; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands., Nijman HW; University of Groningen, University Medical Center Groningen, Department of Obstetrics and Gynecology, The Netherlands. Electronic address: h.w.nijman@umcg.nl.

Publikováno v: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2016 Jun; Vol. 60, pp. 1-11. Date of Electronic Publication: 2016 Mar 31.