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Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

Autor: Cortes, Adrian, Pulit, Sara L., Leo, Paul J., Pointon, Jenny J., Robinson, Philip C., Weisman, Michael H., Ward, Michael, Gensler, Lianne S., Zhou, Xiaodong, Garchon, Henri-Jean, Chiocchia, Gilles, Nossent, Johannes, Lie, Benedicte Alexandra, Førre, Øystein Thorleiv, Tuomilehto, Jaakko, Laiho, Kari, Bradbury, Linda A., Elewaut, Dirk, Burgos-Vargas, Ruben, Stebbings, Simon, Appleton, Louise, Farrah, Claire, Lau, Jonathan, Haroon, Nigil, Mulero, Juan, Blanco, Francisco J., González-Gay, Miguel A., López-Larrea, Carlos, Bowness, Paul, Gaffney, Karl, Gaston, Hill, Gladman, Dafna D., Rahman, Proton, Maksymowych, Walter P., Crusius, J. Bart A., van der Horst-Bruinsma, Irene E., Valle-Oñate, Raphael, Romero-Sánchez, Consuelo, Myrnes, Inger, Pimentel-Santos, Fernando M., Inman, Robert D., Martin, Javier, Breban, Maxime, Wordsworth, Bryan Paul, Reveille, John D., Evans, David M., de Bakker, Paul I.W., Brown, Matthew A.

Publikováno v: Cortes, Adrian Pulit, Sara L. Leo, Paul J. Pointon, Jenny J. Robinson, Philip C. Weisman, Michael H. Ward, Michael Gensler, Lianne S. Zhou, Xiaodong Garchon, Henri-Jean Chiocchia, Gilles Nossent, Johannes Lie, Benedicte Alexandra Førre, Øystein Thorleiv Tuomilehto, Jaakko Laiho, Kari Bradbury, Linda A. Elewaut, Dirk Burgos-Vargas, Ruben Stebbings, Simon Appleton, Louise Farrah, Claire Lau, Jonathan Haroon, Nigil Mulero, Juan Blanco, Francisco J. González-Gay, Miguel A. López-Larrea, Carlos Bowness, Paul Gaffney, Karl Gaston, Hill Gladman, Dafna D. Rahman, Proton Maksymowych, Walter P. Crusius, J. Bart A. van der Horst-Bruinsma, Irene E. Valle-Oñate, Raphael Romero-Sánchez, Consuelo Myrnes, Inger Pimentel-Santos, Fernando M. Inman, Robert D. Martin, Javier Breban, Maxime Wordsworth, Bryan Paul Reveille, John D. Evans, David M. de Bakker, Paul I.W. Brown, Matthew A. . Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1. Nature Communications. 2015, 6
Nature Communications

Externí odkaz: http://hdl.handle.net/10852/102631

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Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.

Autor: Cortes A; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia., Pulit SL; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584, The Netherlands., Leo PJ; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia., Pointon JJ; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK., Robinson PC; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia., Weisman MH; Department of Medicine/Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA., Ward M; Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892-1468, USA., Gensler LS; Department of Medicine/Rheumatology, University of California, San Francisco, California 94143, USA., Zhou X; Department of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA., Garchon HJ; 1] INSERM UMR 1173, Université de Versailles Saint Quentin en Yvelines, Laboratoire d'excellence Inflamex, Saint-Quentn-En-Yvelines 78180, France [2] Genetics Division, Hôpital Ambroise Paré, AP-HP, and Université de Versailles Saint Quentin en Yvelines, Boulogne-Billancourt 78180, France., Chiocchia G; INSERM UMR 1173, Université de Versailles Saint Quentin en Yvelines, Laboratoire d'excellence Inflamex, Saint-Quentn-En-Yvelines 78180, France., Nossent J; 1] School of Medicine, University of Western Australia, Perth, WA 6009, Australia [2] Department of Rheumatology, Sir Charles Gairdner Hospital, Perth, WA 6009, Australia., Lie BA; 1] Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo 0310, Norway [2] Department of Immunology, Oslo University Hospital, Oslo 0310, Norway., Førre Ø; Department of Rheumatology, Oslo University Hospital, and University of Oslo, Oslo 0310, Norway., Tuomilehto J; 1] Department of Chronic Disease Prevention, National Institute for Health and Welfare, 00271 Helsinki, Finland [2] Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria [3] Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia., Laiho K; Department of Medicine, Paijat-Hame Central Hospital, Lahti, Finland., Bradbury LA; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia., Elewaut D; 1] Department of Rheumatology, Gent University Hospital, Gent 9052, Belgium [2] VIB Inflammation Research Center, Ghent University, Gent 9052, Belgium., Burgos-Vargas R; Department of Rheumatology, Hospital General de Mexico and Universidad Nacional Autonoma de Mexico, Mexico City 06726, Mexico., Stebbings S; Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand., Appleton L; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK., Farrah C; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK., Lau J; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK., Haroon N; Division of Rheumatology, Toronto Western Hospital, University of Toronto, Toronto M5T2S8, Canada., Mulero J; Department of Rheumatology, Hospital Puerta de Hierro, Madrid 28222, Spain., Blanco FJ; Department of Rheumatology, Complejo Hospitalario La Coruña, INIBIC, La Coruña 15006, Spain., Gonzalez-Gay MA; Department of Rheumatology, Hospital Marques de Valcecillas, IFIMAV, Santander 39008, Spain., Lopez-Larrea C; 1] Department of Immunology, Hospital Universitario Central de Asturias, Oviedo 33011, Spain [2] Fundación Renal 'Iñigo Álvarez de Toledo', Madrid 33011, Spain., Bowness P; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK., Gaffney K; Department of Rheumatology, Norfolk and Norwich University Hospital, Norwich NR4 7UY, UK., Gaston H; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Cambridge CB2 0SP, UK., Gladman DD; 1] Division of Rheumatology, University of Toronto, Toronto, ON M4N 3M5, Canada [2] Toronto Western Research Institute, Toronto ON M4N 3M5, Canada [3] Psoriatic Arthritis Program, University Health Network, Toronto ON M4N 3M5, Canada., Rahman P; Memorial University of Newfoundland, Newfoundland NL A1B 3X9, Canada., Maksymowych WP; Department of Medicine, University of Alberta, Alberta T6G 2R7, Canada., Crusius JB; Department of Medical Microbiology and Infection Control, Laboratory of Immunogenetics, VU University Medical Center, Amsterdam 1081 BT, The Netherlands., van der Horst-Bruinsma IE; Department of Rheumatology, VU University Medical Centre, Amsterdam 1081 BT, Netherlands., Valle-Oñate R; Spondyloarthropaty Group-Division of Rheumatology, Hospital Militar Central/Universidad de La Sabana, Transversal 3 # 49-00, Bogotá, NA, Colombia., Romero-Sánchez C; Spondyloarthropaty Group-Division of Rheumatology, Hospital Militar Central/Universidad de La Sabana, Transversal 3 # 49-00, Bogotá, NA, Colombia., Hansen IM; Helgelandssykehuset, 8613 Mo i Rana, Norway., Pimentel-Santos FM; Chronic Diseases Research Centre (CEDOC), Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa 1169-056, Portugal., Inman RD; Division of Rheumatology, Toronto Western Hospital, University of Toronto, Toronto M5T2S8, Canada., Martin J; Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones-Científicas, Granada 18100, Spain., Breban M; 1] INSERM UMR 1173, Université de Versailles Saint Quentin en Yvelines, Laboratoire d'excellence Inflamex, Saint-Quentn-En-Yvelines 78180, France [2] Division of Rheumatology, Hôpital Ambroise Paré, AP-HP, and Université de Versailles Saint Quentin en Yvelines, Boulogne-Billancourt 92100, France., Wordsworth BP; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK., Reveille JD; Department of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA., Evans DM; 1] University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia [2] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK [3] School of Social and Community Medicine, University of Bristol, Bristol, UK., de Bakker PI; 1] Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584, The Netherlands [2] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Brown MA; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia.

Publikováno v: Nature communications [Nat Commun] 2015 May 21; Vol. 6, pp. 7146. Date of Electronic Publication: 2015 May 21.