Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Woon S. Choi"'
Publikováno v:
Experimental & Molecular Medicine. 38:494-501
In a murine model of systemic lupus erythematosus (SLE)-like chronic graft-versus-host disease (cGVHD), donor CD8? T cells rapidly fall into anergy to host cells, while donor CD4? T cells hyperactivate B cells and break B-cell tolerance to self-Ags i
Autor:
Hye Jin Kim, Woon S. Choi, Shimon Sakaguchi, Jae-Hee Suh, Hyun Goo Kang, Byungsuk Kwon, Juyang Kim
Publikováno v:
The Journal of Immunology. 176:5223-5231
In this study, we investigated the effect of an agonistic mAb (DTA-1) against glucocorticoid-induced TNF receptor (GITR) in a murine model of systemic lupus erythematosus-like chronic graft-vs-host disease (cGVHD). A single dose of DTA-1 inhibited th
Publikováno v:
Experimental & Molecular Medicine. 38:94-99
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive activity of the subset. In thi
Autor:
Byungsuk Kwon, Juyang Kim, Soojin La, Byoung S. Kwon, Byoung-Sam Kim, Hong R. Cho, Woon S. Choi, Jae-Hee Suh
Publikováno v:
Blood. 105:2206-2213
4-1BB, a member of the tumor necrosis factor (TNF) receptor superfamily, is a costimulator for activated T cells. Previous studies have established that treatment with agonistic anti–4-BB monoclonal antibody (3H3) is effective in reversing the prog
Autor:
Juyang Kim, Shimon Sakaguchi, Byungsuk Kwon, Hawk Kim, Woon S. Choi, Hye Jin Kim, Jae-Hee Suh
Publikováno v:
Blood. 106:1315-1315
In this study, we investigated the effect of an agonistic mAb (DTA-1) against glucocorticoid-induced tumor necrosis factor receptor (GITR) in a murine model of systemic lupus erythematosus (SLE)-like chronic graft-versus-host disease (cGVHD). A singl