Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Woon Ling Chan"'
Autor:
Dusan Popadic, Woon Ling Chan, Athanassios Vratimos, Shizuo Akira, Sang Hee Lee, Kiyoshi Takeda, Nada Pejnovic
Publikováno v:
Molecular Immunology. 47:37-45
Recent reports show T helper 17 (Th17) cells are involved in the pathogenesis of various chronic inflammatory diseases formerly categorized as Th1-mediated disorders. Interleukin-18 (IL-18) induces Th1 cells to produce interferon-gamma (IFN-gamma) wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aa584eaeba3d3f8d6c7a76e413c7d5
https://doi.org/10.1016/j.molimm.2008.12.032
https://doi.org/10.1016/j.molimm.2008.12.032
Autor:
Dusan Popadic, Nada Pejnovic, Tze Vun Liew, Shazia M. Khan, Hamish Hamilton, Alessandro Poggi, Woon Ling Chan
Publikováno v:
Circulation Research. 96:675-683
Immune cell infiltration, vascular smooth muscle cell (VSMC) proliferation, and apoptosis are pathological hallmarks of atherosclerosis. The multifocal, chronic, and inflammatory nature of this disease of the cardiovascular system complicates targete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be825516338c20b28d8cfc9b7efbb1cd
https://doi.org/10.1161/01.res.0000160543.84254.f1
https://doi.org/10.1161/01.res.0000160543.84254.f1
Publikováno v:
European Journal of Immunology. 31:2979-2985
T1/ST2L, an IL-1 receptor homologue, is selectively expressed on murine Th2 cells and specific anti-ST2L antibodies can profoundly modulate the Th1/Th2 balance in vivo. Naive CD4(+) T cells do not express ST2L but do so on activation with specific an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31fe9a6611222a05b7cd7cb995f82018
https://doi.org/10.1002/1521-4141(2001010)31:10<2979::aid-immu2979>3.0.co
https://doi.org/10.1002/1521-4141(2001010)31:10<2979::aid-immu2979>3.0.co
Autor:
Damo Xu, Foo Y. Liew, Iain B. McInnes, Kristy Kennedy, Woon Ling Chan, Max Field, J. Alastair Gracie, A. Gilmour, Bernard P. Leung, Morag R. Greer, Robert W. Carter, Xiao-Qing Wei, Rosalyn J. Forsey, Alan Foulis
Publikováno v:
Journal of Clinical Investigation. 104:1393-1401
IL-18 is a novel cytokine with pleiotropic activities critical to the development of T-helper 1 (Th1) responses. We detected IL-18 mRNA and protein within rheumatoid arthritis (RA) synovial tissues in significantly higher levels than in osteoarthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7b3f808cafd7a4a0012676261897a8
https://doi.org/10.1172/jci7317
https://doi.org/10.1172/jci7317
Autor:
Bernard P. Leung, Robert W. Carter, Iain B. McInnes, Foo Y. Liew, David Hunter, John H. Robinson, Woon Ling Chan, Damo Xu, Kerstin Schulz
Publikováno v:
The Journal of Experimental Medicine
Interleukin (IL)-18 induces interferon (IFN)-gamma synthesis and synergizes with IL-12 in T helper type 1 (Th1) but not Th2 cell development. We report here that IL-18 receptor (IL-18R) is selectively expressed on murine Th1 but not Th2 cells. IL-18R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318910157a0b3e7224edead22e0cbcc1
https://doi.org/10.1084/jem.188.8.1485
https://doi.org/10.1084/jem.188.8.1485
Autor:
Woon Ling Chan, Angela Rodgers, Chris Grief, Neil Almond, Sally Ellis, Brian Flanagan, Peter Silvera, Janet Bootman, James Stott, Karen Kent, Robert Bomford
Publikováno v:
AIDS. 9:223-228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a98086e66463db62829f9f9bda699a
https://doi.org/10.1097/00002030-199509030-00002
https://doi.org/10.1097/00002030-199509030-00002
Autor:
Graham Farrar, Angela Rodgers, Peter Anthony Kitchin, F. Y. Liew, Woon Ling Chan, Robert D. Hancock, Frank Taffs
Publikováno v:
The Journal of Experimental Medicine
Our earlier reports demonstrated that Cynomolgus macaques vaccinated with either inactivated partially purified simian immunodeficiency virus (SIV), fixed SIV-infected C8166 (a human T lymphoblastoid cell line) cells, or fixed uninfected C8166 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5514ba9561d3806860ced8edb4336e83
http://europepmc.org/articles/PMC2119400
http://europepmc.org/articles/PMC2119400
Autor:
P.A. Kitchin, P. J. Greenaway, Martin Cranage, E.J. Stott, Mark Page, F. Taffs, Khg Mills, Woon Ling Chan
Publikováno v:
The Lancet. 336:1538-1541
Cynomolgus macaques were vaccinated with inactivated simian immunodeficiency virus-infected cells and 'Quil-A' as adjuvant at 0,4,8, and 36 weeks or at 0, 4, 8, and 16 weeks. 2 weeks later these animals, together with a similar unvaccinated group, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef492268d3558d97538029a1e0f48a92
https://doi.org/10.1016/0140-6736(90)93310-l
https://doi.org/10.1016/0140-6736(90)93310-l
Publikováno v:
Cellular immunology. 233(2)
Abdominal aortic aneurysm (AAA) is a complex remodeling process that involves both synthesis and degradation of extracellular matrix proteins in the aortic wall, leading to decreased tensile strength, progressive dilation and eventual rupture. Chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4ddfd7d5a27b4eac6aa6720e639119
https://pubmed.ncbi.nlm.nih.gov/15963967
https://pubmed.ncbi.nlm.nih.gov/15963967
Autor:
Tze Vun Liew, Woon Ling Chan, Richard Groves, Christine A. Lee, Hamish Hamilton, Nada Pejnovic
Publikováno v:
Immunology letters. 85(2)
We recently identified two stably expressed cell surface markers, IL-18R and ST2L, which are selectively expressed on T1/NK1 and T2/NK2 cells, respectively. Here we use these molecules in direct ex vivo analysis of PBMCs from patients with AIDS, psor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a46883d7ebc9e4aca5971abbed45b43
https://pubmed.ncbi.nlm.nih.gov/12527223
https://pubmed.ncbi.nlm.nih.gov/12527223