Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Woon Khiong, Chan"'
Autor:
Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin-Han Loh, Omer An, Henry He Yang, Veerabrahma Pratap Seshachalam, Judice L. Y. Koh, Woon-Khiong Chan, Shi Yan Ng, Boon Seng Soh
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background Tissue organoids generated from human pluripotent stem cells are valuable tools for disease modelling and to understand developmental processes. While recent progress in human cardiac organoids revealed the ability of these stem c
Externí odkaz:
https://doaj.org/article/05148704b297449b9cdbc013e856a7a4
Akademický článek
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Autor:
Pradeep Gautam, Kiyofumi Hamashima, Ying Chen, Yingying Zeng, Bar Makovoz, Bhav Harshad Parikh, Hsin Yee Lee, Katherine Anne Lau, Xinyi Su, Raymond C. B. Wong, Woon-Khiong Chan, Hu Li, Timothy A. Blenkinsop, Yuin-Han Loh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
A comprehensive analysis of the ocular networks among various tissues is necessary to understand eye physiology in health and disease. Here the authors present a multi-species single-cell transcriptomic atlas consisting of cells of the cornea, iris,
Externí odkaz:
https://doaj.org/article/90aabc87256046d2ac0a0db19b2e943e
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Medical research in the recent years has achieved significant progress due to the increasing prominence of organoid technology. Various developed tissue organoids bridge the limitations of conventional 2D cell culture and animal models by recapitulat
Externí odkaz:
https://doaj.org/article/e1efb5545d6b48ccb3b29587391405fb
Autor:
Jeremy K.S. Pang, Sabrina Chia, Jinqiu Zhang, Piotr Szyniarowski, Colin Stewart, Henry Yang, Woon-Khiong Chan, Shi Yan Ng, Boon-Seng Soh
Publikováno v:
Stem Cell Reports. 17:1810-1823
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a9be9124ca7f0f41d545aa4ec192804
https://doi.org/10.1016/j.stemcr.2022.06.005
https://doi.org/10.1016/j.stemcr.2022.06.005
Autor:
Shi-Yan Ng, Jin-Hui Hor, Colin L. Stewart, Omer An, Lee Chuen Liew, Beatrice Xuan Ho, Hongbing Yu, Boon Seng Soh, Henry He Yang, Jeremy Kah Sheng Pang, Woon-Khiong Chan, Piotr Szyniarowski, Christina Ying Yan Lim
Publikováno v:
Stem Cell Reports
Summary The immature characteristics and metabolic phenotypes of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) restrict their applications for disease modeling, drug discovery, and cell-based therapy. Leveraging on the metabolic shift
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5e4ca1b9fbf90e416441129c44caf7
https://doi.org/10.1016/j.stemcr.2021.10.009
https://doi.org/10.1016/j.stemcr.2021.10.009
Autor:
Bar Makovoz, Pradeep Gautam, Katherine Anne Lau, Raymond C.B. Wong, Hu Li, Xinyi Su, Yuin-Han Loh, Hsin Yee Lee, Timothy A. Blenkinsop, Ying Chen, Woon-Khiong Chan, Kiyofumi Hamashima, Bhav Harshad Parikh, Yingying Zeng
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The retina is a widely profiled tissue in multiple species by single-cell RNA sequencing studies. However, integrative research of the retina across species is lacking. Here, we construct the first single-cell atlas of the human and porcine ocular co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fa9f95cb4f031daa4b94f5089e3126
https://doi.org/10.1038/s41467-021-25968-8
https://doi.org/10.1038/s41467-021-25968-8
Autor:
Mark Richards, Chee Wee Phoon, Gwendoline Tze Wei Goh, Eng Khuan Seng, Xu Ming Guo, Cherine Mei Fong Tan, Woon-Khiong Chan, Joel Mun Kin Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e85039 (2014)
A major concern in Pluripotent Stem Cell (PSC)-derived cell replacement therapy is the risk of teratoma formation from contaminating undifferentiated cells. Removal of undifferentiated cells from differentiated cultures is an essential step before PS
Externí odkaz:
https://doaj.org/article/048b4d854e9b49408cea7c3fbd6eb2c2
Publikováno v:
FEBS Letters, 593, 3244-3252. John Wiley & Sons, Ltd
FEBS Letters, 593, 23, pp. 3244-3252
FEBS Letters, 593, 23, pp. 3244-3252
Contains fulltext : 214027.pdf (Publisher’s version ) (Closed access) Blood reprogramming, in which induced pluripotent stem cells (iPSCs) are derived from haematopoietic lineages, has rapidly advanced over the past decade. Since the first report u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e803f171c154d87000e17e479c0a360
https://doi.org/10.1002/1873-3468.13659
https://doi.org/10.1002/1873-3468.13659
