Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Woon Chee, Yee"'
Autor:
Keng Boon Wee, Zacharias Aloysius Dwi Pramono, Jian Li Wang, Karl F MacDorman, Poh San Lai, Woon Chee Yee
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1844 (2008)
Antisense oligonucleotides (AONs) mediated exon skipping offers potential therapy for Duchenne muscular dystrophy. However, the identification of effective AON target sites remains unsatisfactory for lack of a precise method to predict their binding
Externí odkaz:
https://doaj.org/article/127391977cec476bb0f82619b787c6d9
Autor:
Peng Wen, Pao, Keng Boon, Wee, Woon Chee, Yee, Zacharias Aloysius Dwi, Pramono, Zacharias Aloysius, Dwipramono
Publikováno v:
Molecular Therapy. 22:854-861
Spinal muscular atrophy (SMA) is a fatal autosomal recessive disease caused by survival motor neuron (SMN) protein insufficiency due to SMN1 mutations. Boosting SMN2 expression is a potential therapy for SMA. SMN2 has identical coding sequence as SMN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07428c7d391d10b65a617de35df75403
https://doi.org/10.1038/mt.2013.276
https://doi.org/10.1038/mt.2013.276
Autor:
Woon-Chee Yee1 yee.woon.chee@sgh.com.sg
Publikováno v:
Neurology India. Jul2008, Vol. 56 Issue 3, p333-338. 6p.
Autor:
Woon Chee Yee, Qian Bin Xiong, Jian Li Wang, Zacharias A.D. Pramono, Poh San Lai, Yi Jun Chen, Keng Boon Wee
Publikováno v:
Human Gene Therapy. 23:781-790
Antisense oligonucleotide (AON)-mediated exon skipping to restore dystrophin expression in Duchenne muscular dystrophy (DMD) therapy shown promise in a number of human clinical trials. Current AON design methods are semi-empirical, involving either t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef2fa95efa76d9e2cef7ed85ef5403d
https://doi.org/10.1089/hum.2011.205
https://doi.org/10.1089/hum.2011.205
Autor:
Poh San Lai, Siok Yuen Kam, Woon Chee Yee, Irene Ai Lian Seah, Zacharias Aloysius Dwi Pramono, Joseph Shean Long See, Chin Lai Tan
Publikováno v:
Human Genetics. 125:413-420
In conducting dysferlin mutational screening using blood mRNA instead of genomic DNA, we identified the occurrence of alternative splicing involving novel dysferlin exons, i.e. exons 5a and 40a, in addition to previously reported alternative splicing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9331095fd9de35d9e8ed8ed506d92826
https://doi.org/10.1007/s00439-009-0632-y
https://doi.org/10.1007/s00439-009-0632-y
Autor:
Xiaoyun Xu, Shu Wang, Jieming Zeng, Woon-Chee Yee, Xu Wang, Chao-Yang Wang, Yee-Kong Ng, Peter Y.K. Hwang
Publikováno v:
Molecular Therapy. 12(2):314-320
Gene delivery to sensory neurons of the dorsal root ganglion (DRG) offers the prospect of developing new clinical interventions against peripheral nerve diseases and disorders. Here we show that genes can be transferred to rat DRG through lumbar intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89eb34681d0d9269df90a35e573855da
Autor:
Tchoyoson C.C. Lim, Wing Lok Au, Ngai Kun Loh, Pei Lin Koh, Dennis C.C. Seow, Maria S. F. Lim, Woon Chee Yee, It Koon Tan
Publikováno v:
Journal of the Neurological Sciences. 209:101-104
A 25-year-old Chinese man presented with a 2-year history of recurrent coma. His plasma ammonia level was extremely elevated, with raised citrulline level and absence of argininosuccinic acid. Adult-onset citrullinaemia, a condition rarely reported o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360b475fe0ac1d986115651e426b7f8c
https://doi.org/10.1016/s0022-510x(02)00439-2
https://doi.org/10.1016/s0022-510x(02)00439-2
Publikováno v:
Muscle & Nerve. 21:1216-1219
N lines can be seen by electron microscopy within the I band of skeletal muscle, but are poorly visualized in conventional preparations. We present a case of acute quadriplegic myopathy with myosin loss and prominent N lines. The only other reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a1af489dc1dba1c871aae2f274dd263
https://doi.org/10.1002/(sici)1097-4598(199809)21:9<1216::aid-mus17>3.0.co
https://doi.org/10.1002/(sici)1097-4598(199809)21:9<1216::aid-mus17>3.0.co
Autor:
Andrew J. Kornberg, Lloyd K. Shield, Yoram Nevo, Alan Pestronk, Woon-Chee Yee, Imran Iqbal, Anne M. Connolly
Publikováno v:
Neurology. 47:98-102
Chronic inflammatory demyelinating neuropathy (CIDP) is a rare disease in childhood.We reviewed the clinical characteristics, response to therapy, and long-term prognosis in 13 children (1.5 to 16 years of age) diagnosed with CIDP at Washington Unive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e81619c3880f8decdb036d436a8a13e
https://doi.org/10.1212/wnl.47.1.98
https://doi.org/10.1212/wnl.47.1.98
Publikováno v:
Journal of the Neurological Sciences. 112:133-138
Herein we described a family with X-linked spinal and bulbar muscular dystrophy (SBMA or Kennedy's disease), an adult onset neuromuscular disease characterized by slow progression, predominat proximal and bulbar muscle weakness. One frequent associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376b04b2ca8f65b88bcbaf7f7271cee9
https://doi.org/10.1016/0022-510x(92)90142-8
https://doi.org/10.1016/0022-510x(92)90142-8