Výsledky vyhledávání - "Woon‐Hae Kim"

Akademický článek

Anti-fibrotic Effects of Synthetic Oligodeoxynucleotide for TGF-β1 and Smad in an Animal Model of Liver Cirrhosis

Autor: Jung-Yeon Kim, Hyun-Jin An, Woon-Hae Kim, Mi-Gyeong Gwon, Hyemin Gu, Yoon-Yub Park, Kwan-Kyu Park

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 250-263 (2017)

Liver fibrosis is characterized by changes in tissue architecture and extracellular matrix composition. Liver fibrosis affects not only hepatocytes but also the non-parenchymal cells such as hepatic stellate cells (HSCs), which are essential for main

Externí odkaz: https://doaj.org/article/7a71440ad1334e8c974c229e8bec65f4

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Akademický článek

Microslit on a chip: A simplified filter to capture circulating tumor cells enlarged with microbeads.

Autor: Seung Joon Lee, Tae Seok Sim, Hyun Young Shin, Jungmin Lee, Min Young Kim, Joseph Sunoo, Jeong-Gun Lee, Kyungmoo Yea, Young Zoon Kim, Danny van Noort, Soo Kyung Park, Woon-Hae Kim, Kyun Woo Park, Minseok S Kim

Publikováno v: PLoS ONE, Vol 14, Iss 10, p e0223193 (2019)

Microchips are widely used to separate circulating tumor cells (CTCs) from whole blood by virtues of sophisticated manipulation for microparticles. Here, we present a chip with an 8 μm high and 27.9 mm wide slit to capture cancer cells bound to 3 μ

Externí odkaz: https://doaj.org/article/4bb192a408e04ca197d2be2fadf63496

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Akademický článek

Antifibrotic Effect of Smad Decoy Oligodeoxynucleotide in a CCl4-Induced Hepatic Fibrosis Animal Model

Autor: Mi-Gyeong Gwon, Jung-Yeon Kim, Hyun-Jin An, Woon-Hae Kim, Hyemin Gu, Min-Kyung Kim, Sok Cheon Pak, Kwan-Kyu Park

Publikováno v: Molecules, Vol 23, Iss 8, p 1991 (2018)

Hepatic fibrosis is the wound-healing process of chronic hepatic disease that leads to the end-stage of hepatocellular carcinoma and demolition of hepatic structures. Epithelial–mesenchymal transition (EMT) has been identified to phenotypic convers

Externí odkaz: https://doaj.org/article/c0f64ed56692485f9eaf7d5283cee453

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Akademický článek

Anti-Inflammatory Effect of Melittin on Porphyromonas Gingivalis LPS-Stimulated Human Keratinocytes

Autor: Woon-Hae Kim, Hyun-Jin An, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyemin Gu, Minji Jeon, Min-Kyung Kim, Sang-Mi Han, Kwan-Kyu Park

Publikováno v: Molecules, Vol 23, Iss 2, p 332 (2018)

Periodontitis is a chronic inflammatory disease that contributes to the destruction of the gingiva. Porphyromonas gingivalis (P. gingivalis) can cause periodontitis via its pathogenic lipopolysaccharides (LPS). Melittin, a major component of bee veno

Externí odkaz: https://doaj.org/article/be5a6094941142cfa8444d03a24c85e0

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Akademický článek

Bee Venom Inhibits Porphyromonas gingivalis Lipopolysaccharides-Induced Pro-Inflammatory Cytokines through Suppression of NF-κB and AP-1 Signaling Pathways

Autor: Woon-Hae Kim, Hyun-Jin An, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyemin Gu, Jae-Bok Park, Woo Jung Sung, Yong-Chul Kwon, Kyung-Duck Park, Sang Mi Han, Kwan-Kyu Park

Publikováno v: Molecules, Vol 21, Iss 11, p 1508 (2016)

Periodontitis is a chronic inflammatory disease that leads to destruction of tooth supporting tissues. Porphyromonas gingivalis (P. gingivalis), especially its lipopolysaccharides (LPS), is one of major pathogens that cause periodontitis. Bee venom (

Externí odkaz: https://doaj.org/article/fecc0a75cae84fbfbceab26281daebfe

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Akademický článek

The Protective Effect of Melittin on Renal Fibrosis in an Animal Model of Unilateral Ureteral Obstruction

Autor: Hyun-Jin An, Jung-Yeon Kim, Woon-Hae Kim, Sang-Mi Han, Kwan-Kyu Park

Publikováno v: Molecules, Vol 21, Iss 9, p 1137 (2016)

Renal fibrosis is the principal pathological process underlying the progression of chronic kidney disease that leads to end-stage renal disease. Melittin is a major component of bee venom, and it has anti-bacterial, anti-viral, and anti-inflammatory

Externí odkaz: https://doaj.org/article/8f1f7d4a466e467495676fbb630e28c7

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