Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Woomi Kim"'
Autor:
Anna Shiriaeva, Daejin Park, Gyudong Kim, Yoonji Lee, Xiyan Hou, Dnyandev B. Jarhad, Gibae Kim, Jinha Yu, Young Eum Hyun, Woomi Kim, Zhan-Guo Gao, Kenneth A. Jacobson, Gye Won Han, Raymond C. Stevens, Lak Shin Jeong, Sun Choi, Vadim Cherezov
Publikováno v:
Journal of Medicinal Chemistry. 65:11648-11657
Publikováno v:
Journal of Life Science. 22:1456-1462
Sorafenib is a multikinase inhibitor and an oral anticancer drug approved for the treatment of patients with advanced renal cell carcinoma and those with unresectable hepatocellular carcinoma. The purpose of this study was to develop an efficient met
Autor:
Woomi Kim, Dae Jin Park
Publikováno v:
Journal of Life Science. 19:1698-1704
Gemcitabine is an anticancer drug used to treat a variety of solid tumors. The drug is rapidly inactivated by cytidine deaminase in plasma and its hydrophilicity restricts the extent of quantification that is possible using reversed-phase liquid chro
Publikováno v:
Journal of Life Science. 19:1514-1521
To evaluate the feasibility of cathepsin-B levels in preoperatively screening patients with thyroid cancer, we assigned these patients to either the thyroid cancer group (n=32) or the nodular hyperplasia group (n=7). Five healthy volunteers served as
Autor:
Woomi Kim
Publikováno v:
Journal of Life Science. 19:1226-1231
Enzyme substitution with recombinant phenylalanine ammonia-lyase (PAL, EC 4.3.1.5) is currently being explored for treatment of phenylketonuria (PKU), an autosomal recessive genetic disorder with mutations of the gene encoding phenylalanine-4-hydroxy
Autor:
Jung-Eun Kim, Young-Ran Yoon, Dae Jin Park, In-Jin Jang, Song Cui, Sung-Kyu Hwang, Woomi Kim, Byung-Jo Moon, Prasad Phapale
Publikováno v:
Chromatographia. 68:187-192
A rapid, specific, and sensitive ultra-performance liquid chromatographic method for analysis of levofloxacin in human plasma has been developed and validated. Plasma samples were spiked with the internal standard (enoxacin) and extracted with 10:1 (
Autor:
Sung Mook Lim, Mi-sun Lim, Dong Heon Yang, Woomi Kim, Joomi Lee, Sung Min Park, Mi-Ri Gwon, Hyun-Ju Kim, Hae Won Lee, Young-Ran Yoon, Sook Jin Seong
Publikováno v:
International journal of clinical pharmacology and therapeutics. 53(6)
Background Imatinib mesylate (IM) is a selective tyrosine kinase inhibitor for the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors. A new once-daily 400-mg film-coated tablet of imatinib has been developed by a pharmaceutica
Autor:
Young-Ran Yoon, Sook Jin Seong, Joomi Lee, Mi Sun Lim, Hee Doo Yoo, Seunghoon Han, Woomi Kim, Sung Min Park, Sung Min Lee, Mi Ri Gwon
Publikováno v:
Translational and Clinical Pharmacology. 23:66
+ The first two authors contributed equally to this work. The objective of this study was to develop a population pharmacokinetic (PK) model for sumat - riptan, which frequently shows an atypical absorption profile with multiple peaks. Sumatriptan, a
Autor:
Lin Chen, Alejandra Gámez, Paul A. Fitzpatrick, Lin Wang, Christineh N. Sarkissian, Mary Straub, Steve Striepeke, Charles A. O'Neill, Charles R. Scriver, Jeffrey F. Lemontt, Raymond C. Stevens, Marianne G. Patch, Woomi Kim
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 11(6)
Phenylketonuria (PKU) is a metabolic disorder due primarily to mutations in the PAH gene that impair both phenylalanine hydroxylase activity and disposal of l-phenylalanine from the normal diet. Excess phenylalanine is toxic to cognitive development
Autor:
Raymond C. Stevens, Stephen K. Tyring, Sankar Surendran, Heidi Erlandsen, Woomi Kim, Reuben Matalon, Alejandra Gámez, Kimberlee Michols-Matalon
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 10(2)
Phenylketonuria (PKU) is an inborn error of amino acid metabolism caused by phenylalanine hydroxylase (PAH) deficiency. Dietary treatment has been the cornerstone for controlling systemic phenylalanine (Phe) levels in PKU for the past 4 decades. Over