Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Wook-Bin Lee"'
Autor:
Tam Thi Le, Jonghwan Kim, Tae Kyeom Kang, Wook-Bin Lee, Myungsuk Kim, Chung Sub Kim, Sang Hoon Jung
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 35170-35181 (2024)
Externí odkaz:
https://doaj.org/article/7f1150c7edc1496284cc67db46953a40
Autor:
Joon Young Jang, Hyung Woo Kim, Ji‐Jing Yan, Tae Kyeom Kang, Wook‐Bin Lee, Beom Seok Kim, Jaeseok Yang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Background Cold ischemia‐reperfusion injury (IRI) is an unavoidable complication of kidney transplantation. We investigated the role of regulatory T cells (Treg) in cold IRI and whether the interleukin (IL)‐2/anti‐IL‐2 antibody compl
Externí odkaz:
https://doaj.org/article/e9e6609437e44f5fb43a7ce1221eba72
Publikováno v:
Applied Sciences, Vol 12, Iss 12, p 6116 (2022)
Lithospermum erythrorhizon (L. erythrorhizon) root is used in traditional medicine for its anti-inflammatory, antibacterial, and antioxidant properties. However, no studies have examined its impact on allergic rhinitis (AR). Here, we explored the pro
Externí odkaz:
https://doaj.org/article/fc423ec04a3f4ef9958afd3738d4ecba
Autor:
Wook-Bin Lee, Ji-Seon Kang, Won Young Choi, Quanri Zhang, Chul Han Kim, Un Yung Choi, Jeongsil Kim-Ha, Young-Joon Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Resolution of granulomas in mycobacterial infection requires macrophages to switch from cytokine to nitric oxide (NO) production. Here the authors show that Mincle stimulates translation of the key NO synthesis genes by a mechanism dependent on p38-m
Externí odkaz:
https://doaj.org/article/ae17c8e545c24eaeac56e1a53a11d707
Autor:
Un Yung Choi, Ji Yeon Hur, Myeong Sup Lee, Quanri Zhang, Won Young Choi, Lark Kyun Kim, Wook-Bin Lee, Goo Taeg Oh, Young-Joon Kim
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95805 (2014)
To avoid excessive activation, immune signals are tightly controlled by diverse inhibitory proteins. TRIM30, a tripartite motif (TRIM)-containing protein is one of such inhibitors known to function in macrophages. To define the roles of TRIM30, we ge
Externí odkaz:
https://doaj.org/article/33927d536c2d4f16bd46950cc8fd3fc5
Autor:
Wook-Bin Lee, Ji-Seon Kang, Ji-Jing Yan, Myeong Sup Lee, Bo-Young Jeon, Sang-Nae Cho, Young-Joon Kim
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002614 (2012)
Trehalose 6,6'-dimycolate (TDM), a cord factor of Mycobacterium tuberculosis (Mtb), is an important regulator of immune responses during Mtb infections. Macrophages recognize TDM through the Mincle receptor and initiate TDM-induced inflammatory respo
Externí odkaz:
https://doaj.org/article/70f3297d06ef4802bd6884ffb8bc6a16
Autor:
Lark Kyun Kim, Un Yung Choi, Hwan Sung Cho, Jung Seon Lee, Wook-bin Lee, Jihyun Kim, Kyoungsuk Jeong, Jaewon Shim, Jeongsil Kim-Ha, Young-Joon Kim
Publikováno v:
PLoS Biology, Vol 5, Iss 9, p e238 (2007)
The activation of several transcription factors is required for the elimination of infectious pathogens via the innate immune response. The transcription factors NF-kappaB, AP-1, and STAT play major roles in the synthesis of immune effector molecules
Externí odkaz:
https://doaj.org/article/a6c87e249fb148fc9632b12232f2879d
Publikováno v:
BioMed Research International.
This study is aimed at investigating the potential molecular features of allergic rhinitis (AR) and identifying gene signatures and related transcription factors using transcriptome analysis and in silico datasets. Transcriptome profiles were obtaine
Publikováno v:
International journal of molecular sciences. 23(18)
In East Asia, the dried root of
Autor:
Chang Yong Lee, Wook-Bin Lee, Tae Kyeom Kang, Chung Hyun Lee, Sang Hoon Jung, Sung Jae Yang, Kyung-A Kim
Publikováno v:
Applied Biological Chemistry. 63
The efficacy of ethanol extract ofDiospyros kaki(EEDK) on dry eye (DE) was determined using an experimental mouse model. Experimental groups included three treated with various amounts of EEDK and one treated with omega-3 for 2 weeks. Damage to the o