Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Wook Joon Chung"'
Autor:
Ana M. Crane, Philipp Kramer, Jacquelin H. Bui, Wook Joon Chung, Xuan Shirley Li, Manuel L. Gonzalez-Garay, Finn Hawkins, Wei Liao, Daniela Mora, Sangbum Choi, Jianbin Wang, Helena C. Sun, David E. Paschon, Dmitry Y. Guschin, Philip D. Gregory, Darrell N. Kotton, Michael C. Holmes, Eric J. Sorscher, Brian R. Davis
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 569-577 (2015)
Recently developed reprogramming and genome editing technologies make possible the derivation of corrected patient-specific pluripotent stem cell sources—potentially useful for the development of new therapeutic approaches. Starting with skin fibro
Externí odkaz:
https://doaj.org/article/3bd18eafc9e34d40b5c4fab5ff9e7a11
Autor:
Hashir Hamza, Harald Sontheimer, Susan A. Lyons, Gina M. Nelson, G. Yancey Gillespie, Wook Joon Chung, Candece L. Gladson
Publikováno v:
The Journal of Neuroscience. 25:7101-7110
Glial cells play an important role in sequestering neuronally released glutamate via Na+-dependent transporters. Surprisingly, these transporters are not operational in glial-derived tumors (gliomas). Instead, gliomas release glutamate, causing excit
Publikováno v:
Journal of Neurochemistry. 66:1273-1281
MAP2, a dendritically localized microtubule-associated protein (MAP), consists of a pair of high molecular mass (280 kDa) polypeptides, MAP2a and MAP2b, and several low molecular mass (70 kDa) proteins called MAP2c. Although MAP2b and MAP2c have been
Autor:
Craig C. Garner, Michael D. Ehlers, Stefan Kindler, Richard L. Huganir, Wook Joon Chung, Andrew L. Mammen, Lit-fui Lau
Publikováno v:
Journal of Biological Chemistry. 271:21622-21628
Ionotropic glutamate receptors are known to cluster at high concentration on the postsynaptic membrane of excitatory synapses, but the mechanism by which this occurs is poorly understood. Studies on the neuromuscular junction and central inhibitory s
Autor:
Lit Fui Lau, Craig C. Garner, Richard L. Huganir, Wook Joon Chung, Eckart D. Gundelfinger, Ute Kistner, Steven D. Fenster, Bettina Müller, Stefan Kindler, R W Veh, Sven Kuhlendahl
Publikováno v:
Neuron. 17(2):255-265
Synapse-associated proteins (SAPs) are constituents of the pre- and postsynaptic submembraneous cytomatrix. Here, we present SAP102, a novel 102 kDa SAP detected in dendritic shafts and spines of asymmetric type 1 synapses. SAP102 is enriched in prep
Autor:
Suk-Tae Kwon, Byoung Chul Park, Dae-Sil Lee, Jeong Heon Ko, Cheorl-Ho Kim, Sukhoon Koh, Wook Joon Chung
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 58:1694-1699
An E. coli expression clone coding for human proinsulin, which was fused to NH2-terminal beta-galactosidase, was engineered for the separation from host proteins by introducing peptide devices, and for the sequential removal of the fused polypeptide
Autor:
Finn Hawkins, Xuan Shirley Li, Philipp Kramer, Wei Liao, Eric J. Sorscher, Philip D. Gregory, Darrell N. Kotton, Brian R. Davis, Jacquelin H. Bui, Wook Joon Chung, Manuel L. Gonzalez-Garay, Jianbin Wang, Helena C. Sun, David Paschon, Daniela Mora, Michael C. Holmes, Ana M. Crane, Dmitry Guschin
Publikováno v:
Molecular Therapy. 23:S74
Recently developed reprogramming and genome editing technologies make possible the derivation of corrected patient-specific pluripotent stem cell sources – potentially useful for the development of new therapeutic approaches. The primary defect in
Autor:
Steven D. Fenster, Craig C. Garner, Eckart D. Gundelfinger, Michael M. Kessels, Britta Qualmann, Joanne E. Nash, Wook Joon Chung
Publikováno v:
The Journal of biological chemistry. 278(22)
Piccolo is a high molecular weight multi-domain protein shown to be a structural component of the presynaptic CAZ (cytoskeletal matrix assembled at active zones). These features indicate that Piccolo may act to scaffold proteins involved in synaptic
Autor:
Gisela Olias, Michael R. Kreutz, Craig C. Garner, Robin A. J. Lester, Stefan Kindler, Eckart D. Gundelfinger, Rong Zhai, Susanne tom Dieck, Wook Joon Chung, Kristina Langnaese
Publikováno v:
Molecular and cellular neurosciences. 15(5)
Bassoon is a 420-kDa presynaptic cytomatrix protein potentially involved in the structural organization of neurotransmitter release sites. In this study, we have investigated a possible role for Bassoon in synaptogenesis and in defining synaptic vesi
Autor:
Claudia Cases-Langhoff, Stefan Kindler, Craig C. Garner, Steven D. Fenster, Udo Kaempf, Eckart D. Gundelfinger, Abigail Garner, Britta Voss, Rong Zhai, Wook Joon Chung
Publikováno v:
Neuron. 25(1)
Piccolo is a novel component of the presynaptic cytoskeletal matrix (PCM) assembled at the active zone of neurotransmitter release. Analysis of its primary structure reveals that Piccolo is a multidomain zinc finger protein structurally related to Ba