Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Woojong Lee"'
Autor:
Woojong Lee, M. Suresh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adjuvants are indispensable components of vaccines for stimulating optimal immune responses to non-replicating, inactivated and subunit antigens. Eliciting balanced humoral and T cell-mediated immunity is paramount to defend against diseases caused b
Externí odkaz:
https://doaj.org/article/9385ed41c44f40f88456ae94b68d5a17
Autor:
Jaeeun Ko, Jaehwan Kim, Yang-Kyu Choi, Sang-Soep Nahm, Jayon Kim, Sun-Min Seo, Jin-Seok Seo, Woojong Lee, Weon Kuu Chung, Kidong Eom
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
This study aimed to evaluate the clinical safety and validate the radiomitigative effect of KMRC011, against radiation-induced oral mucositis in beagle dogs. Clinical safety was evaluated by assessing tolerability, complete blood tests, and plasma bi
Externí odkaz:
https://doaj.org/article/3fadb8c5fefd4766aac51b836be3cb6f
Autor:
Amanda Contreras, Darin L. Wiesner, Brock Kingstad-Bakke, Woojong Lee, John P. Svaren, Bruce S. Klein, M. Suresh
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
FoxP3+ regulatory T cells (Tregs) are essential for self-tolerance and moderating tissue-damaging inflammation. Tregs that develop and mature in the thymus are classified as central Tregs or effector Tregs based on whether Tregs predominately inhabit
Externí odkaz:
https://doaj.org/article/83bcafceba6f46be9ef3fcae48dbc6a2
Autor:
Brock Kingstad-Bakke, Randall Toy, Woojong Lee, Pallab Pradhan, Gabriela Vogel, Chandranaik B. Marinaik, Autumn Larsen, Daisy Gates, Tracy Luu, Bhawana Pandey, Yoshihoro Kawaoka, Krishnendu Roy, M. Suresh
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Eliciting durable and protective T cell-mediated immunity in the respiratory mucosa remains a significant challenge. Polylactic-co-glycolic acid (PLGA)-based cationic pathogen-like particles (PLPs) loaded with TLR agonists mimic biophysical propertie
Externí odkaz:
https://doaj.org/article/67c46005f89f4a50b0ee1e1d7965e5bf
Autor:
Woojong Lee, Brock Kingstad-Bakke, Brett Paulson, Autumn Larsen, Katherine Overmyer, Chandranaik B Marinaik, Kelly Dulli, Randall Toy, Gabriela Vogel, Katherine P Mueller, Kelsey Tweed, Alex J Walsh, Jason Russell, Krishanu Saha, Leticia Reyes, Melissa C Skala, John-Demian Sauer, Dmitry M Shayakhmetov, Joshua Coon, Krishnendu Roy, M Suresh
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009168 (2021)
There is a critical need for adjuvants that can safely elicit potent and durable T cell-based immunity to intracellular pathogens. Here, we report that parenteral vaccination with a carbomer-based adjuvant, Adjuplex (ADJ), stimulated robust CD8 T-cel
Externí odkaz:
https://doaj.org/article/73580a7e1e6e47af817c8a1751850e37
Autor:
Chandranaik B. Marinaik, Brock Kingstad-Bakke, Woojong Lee, Masato Hatta, Michelle Sonsalla, Autumn Larsen, Brandon Neldner, David J. Gasper, Ross M. Kedl, Yoshihiro Kawaoka, M. Suresh
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 6, Pp 100095- (2020)
Summary: Induction of protective mucosal T cell memory remains a formidable challenge to vaccinologists. Using a combination adjuvant strategy that elicits potent CD8 and CD4 T cell responses, we define the tenets of vaccine-induced pulmonary T cell
Externí odkaz:
https://doaj.org/article/88a86e830e69472c8aa0517dd36c33a6
Autor:
Feng Guo, Liling Wan, Aiping Zheng, Vitali Stanevich, Yong Wei, Kenneth A. Satyshur, Minhong Shen, Woojong Lee, Yibin Kang, Yongna Xing
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1704-1713 (2014)
Metadherin (MTDH) and Staphylococcal nuclease domain containing 1 (SND1) are overexpressed and interact in diverse cancer types. The structural mechanism of their interaction remains unclear. Here, we determined the high-resolution crystal structure
Externí odkaz:
https://doaj.org/article/5be36acce8ba4c57b1597e879bd0d2d7
Publikováno v:
ACS Catalysis. 11:12821-12832
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::081af2944e7c0754d48431464990fb50
https://doi.org/10.1021/acscatal.1c03797
https://doi.org/10.1021/acscatal.1c03797
Autor:
Matthew R. Mena, Afshan Khurshid, Mu-Hyun Baik, Andrew Chizmeshya, Suyeon Kim, Thomas L. Groy, Raja Pal, Ryan J. Trovitch, Chandrani Ghosh, Woojong Lee
Publikováno v:
Inorganic Chemistry. 60:7708-7718
Refluxing Mo(CO)6 in the presence of the phosphine-functionalized α-diimine ligand Ph2PPrDI allowed for substitution and formation of the dicarbonyl complex, (Ph2PPrDI)Mo(CO)2. Oxidation with I2 followed by heating resulted in further CO dissociatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cefd27ca0952cf9b681e744f0f4154
https://doi.org/10.1021/acs.inorgchem.1c00003
https://doi.org/10.1021/acs.inorgchem.1c00003
Autor:
Brock Kingstad-Bakke, Woojong Lee, Shaswath S. Chandrasekar, David J. Gasper, Cristhian Salas-Quinchucua, Thomas Cleven, Jeremy A. Sullivan, Adel Talaat, Jorge E. Osorio, M. Suresh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(20)
The first-generation COVID-19 vaccines have been effective in mitigating severe illness and hospitalization, but recurring waves of infections are associated with the emergence of SARS-CoV-2 variants that display progressive abilities to evade antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f3e148c2af486ef82f8d54fdc7f251
https://pubmed.ncbi.nlm.nih.gov/35561224
https://pubmed.ncbi.nlm.nih.gov/35561224