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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Autor: Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, Anorexia Nervosa Genetics Initiative, Hanscombe KB, Purves KL, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Munn-Chernoff MA, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Raquel Rabionet Janssen, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Stuber GD, Gordon S, Grove J, Henders AK, Juréus A, Kirk KM, Larsen JT, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery GW, Wade TD, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin NG, Mortensen PB, Sullivan PF, Breen G, Bulik CM

Publikováno v: NATURE GENETICS
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and serious illness 1 , affecting 0.9-4% of women and 0.3% of men 2-4 , with twin-based heritability estimates of 50-60% 5 . Mortality rates are higher than those in othe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::9bc3d7023103c0303f7cf05f7d227d76
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16446

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Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

Autor: Arvid Lundervold, James A B Floyd, Stephen W. Scherer, Unna N. Danner, Slof-Op ’t Landt M, Julia Huemer, Maurizio Clementi, Smith T, Roger A.H. Adan, George Dedoussis, Anke Hinney, Yiran Guo, Stephan Ripke, Martin A. Kennedy, Matteo Cassina, Richard Parker, Laura Carlberg, Michael Strober, Doris Koubek, Andreas Karwautz, Gun Peggy Knudsen, Janiece E. DeSocio, Franziska Ritschel, Chris Finan, Stefan Ehrlich, Jolanta Lissowska, Roger D. Cone, Christopher S. Franklin, P. B. Mortensen, Allan S. Kaplan, Tetsuya Ando, Neonila Szeszenia-Dabrowska, Dan Rujescu, Nicolas Ramoz, Kyung Im H, Bobby P. C. Koeleman, Andreas Birgegård, Shuyang Yao, Fernando Fernández-Aranda, Monica Forzan, Scott J. Crow, Paolo Santonastaso, Gudrun Wagner, Raquel Rabionet, Laura M. Thornton, Stephanie Zerwas, Elena Tenconi, Carolyn E. Cesta, Esther Walton, Solveig K. Sieberts, André Scherag, Ulrike Schmidt, Sarah Cohen-Woods, Tracey D. Wade, Claudette Boni, James I. Hudson, Pamela Sklar, Paul Lichtenstein, Marie Navratilova, H-Erich W, Fragiskos Gonidakis, Monica G, Aarno Palotie, Judith Hendriks, Gursharan Kalsi, Ioanna Ntalla, Lisa R. Lilenfeld, Leppä, Claes Norring, Steve Gallinger, Karin Egberts, Beate Herpertz-Dahlmann, Cynthia M. Bulik, Samuli Ripatti, Nicholas J. Schork, Zeynep Yilmaz, Robert Sladek, Christopher E. Hilliard, Wolfgang Herzog, Kelly L. Klump, Boraska Perica, Tziouvas K, Jeffrey C. Barrett, Elisa Docampo, Jin P. Szatkiewicz, Laura J. Scott, Anna Keski-Rahkonen, Hana Papezova, Eric R. Gamazon, Nigel W. Rayner, Philippe Courtet, Andrzej Rajewski, Sara Marsal, Bo Ding, Jochen Seitz, Alfonso Tortorella, van Elburg A, de Zwaan M, Konstantinos Hatzikotoulas, Wenhui Wang, Janout, Alexandra Schosser, Danielle M. Dick, Sven Cichon, Jacques Pantel, P.F. Sullivan, Le Hellard S, Robert D. Levitan, Stephan Zipfel, Hidetoshi Inoko, Dimitris Dikeos, Wade H. Berrettini, Anu Raevuori, Roel A. Ophoff, Jenny Jordan, Filip Rybakowski, Palmiero Monteleone, Laura M. Huckins, Daniela Degortes, E. Widen, Lars Klareskog, Douglas M. Ruderfer, Morten Mattingsdal, Jessica H. Baker, Peter McGuffin, Walter H. Kaye, Alessio Maria Monteleone, Ted Reichborn-Kjennerud, Xavier Estivill, Lars A, Eleftheria Zeggini, Nancy J. Cox, Nadia Micali, Craig Johnson, Amanda Dobbyn, Deborah Kaminská, Christian Dina, James E. Mitchell, Benedetta Nacmias, Ioanna Tachmazidou, Melissa A. Munn-Chernoff, Hakon Hakonarson, van Furth E, Kirsty Kiezebrink, Roland Burghardt, Katrin Männik, E Stahl, Jaakko Kaprio, James L. Kennedy, Anders Juréus, Sara McDevitt, Oliver S. P. Davis, Leila Karhunen, Giovanni Gambaro, Geòrgia Escaramís, Bencko, Ole A, Mario Maj, Bernie Devlin, Angela F, Ricca, Ingrid Meulenbelt, Steen, Krista Fischer, Karen S. Mitchell, Katherine A. Halmi, La Via M, Marion Leboyer, Antonio Julià, Ida A. K. Nilsson, Jri Coleman, Eric Strengman, Susana Jiménez-Murcia, Harald N. Aschauer, Mcfadden W, Sandro Sorbi, Agnieszka Słopień, Dong Li, Thomas Espeseth, Lenka Foretová, L. Southam, Hunna J. Watson, Stefan Herms, Johannes Hebebrand, P. Gorwood, James L. Crowley, Sietske G. Helder, Ina Giegling, F. Tozzi, Martien J H Kas, Hartmut Imgart, Monika Dmitrzak-Weglarz, Alessandro Rotondo, Gerome Breen, Julie K. O'Toole, Tõnu Esko, Nicole Soranzo, A. Metspalu, Janet Treasure, Youl-Ri Kim, Joanna Hauser, Manfred M. Fichter, P.E. Slagboom, Steven F Crawford, Pierre J. Magistretti, Sébastien Guillaume, Helena Gaspar, Artemis Tsitsika, Andrew W. Bergen, Marion Roberts, Elisabeth Merl, Woodside Db, Mikael Landén, Harry Brandt, Nicholas G. Martin, L. Slachtova, Dalila Pinto

Anorexia nervosa (AN) is a complex and serious eating disorder, occurring in ~1% of individuals. Despite having the highest mortality rate of any psychiatric disorder, little is known about the aetiology of AN, and few effective treatments exist.Glob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca9ab14add551fab24035aa9ecb85f4
https://doi.org/10.1101/265017

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Anorexia nervosa and bulimia nervosa in children and adolescents

Autor: Woodside Db

Publikováno v: The Journal of Pediatrics. 5:415-418

There are significant advances in many areas in the field of the eating disorders anorexia nervosa and bulimia nervosa. The publication of treatment guidelines by the American Psychiatric Association provides clear direction for clinicians involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63804e99d55177cc4b98e2711651aa5d
https://doi.org/10.1097/00008480-199308000-00006

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Personality in men with eating disorders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::1345c062b73f9ae3b026d15d17b744b5
http://hdl.handle.net/11568/89358

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Significant linkage on chromosome 10p in families with bulimia nervosa

Autor: Bulik, Cm, Devlin, B, Bacanu, Sa, Thornton, L, Klump, Kl, Fichter, Mm, Halmi, Ka, Kaplan, As, Strober, M, Woodside, Db, Bergen, Aw, Mauri, Mauro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::a64a304a0bb19a0a9c431dbbd2d39e21
http://hdl.handle.net/11568/76587

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Salivary Cortisol in Children: Correlations with Serum Values and Effect of Psychotropic Drug Administration

Autor: Sandra Fisman, Woodside Db, Winter K

Publikováno v: The Canadian Journal of Psychiatry. 36:746-748

This study compares the paired serum and salivary cortisol levels of 60 children and adolescents, obtained while performing a routine Dexamethasone Suppression Test. The results reveal significant correlations between serum and salivary cortisol leve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407cb76f63f8b73e78da53544692c059
https://doi.org/10.1177/070674379103601011

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