Improving the diagnosis of severe malaria in African children using platelet counts and plasma Pf HRP2 concentrations

Autor: Williams, T, Watson, J, Uyoga, S, Wanjiku, P, Woodrow, CJ, Day, N, Bejon, P, White, NJ

Severe malaria caused by Plasmodium falciparum is difficult to diagnose accurately in children in high-transmission settings. Using data from 2649 pediatric and adult patients enrolled in four studies of severe illness in three countries (Bangladesh,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::bfd1d40b057f4010e33230e2f2e6903e
https://ora.ox.ac.uk/objects/uuid:6ec51143-4ec4-444b-9590-657f196f2e0d

Strong protective effect of Mediterranean type glucose-6-phosphate dehydrogenase deficiency against vivax malaria

Autor: Awab, GR, Aaram, F, Jamornthanyawat, N, Suwannasin, K, Pagornrat, W, Watson, JA, Woodrow, CJ, Dondorp, A, Day, NP, Imwong, M, White, N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::db057327bdce35c1676f880d155a5c63
https://doi.org/10.4269/ajtmh.abstract2019

The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence : a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis

Autor: Commons, RJ, Simpson, JA, Thriemer, K, Humphreys, GS, Abreha, T, Alemu, SG, Añez, A, Anstey, NM, Awab, GR, Baird, JK, Barber, BE, Borghini-Fuhrer, I, Chu, CS, D'Alessandro, U, Dahal, P, Daher, A, De Vries, PJ, Erhart, A, Gomes, MSM, Gonzalez-Ceron, L, Grigg, MJ, Heidari, A, Hwang, J, Kager, PA, Ketema, T, Khan, WA, Lacerda, MVG, Leslie, T, Ley, B, Lidia, K, Monteiro, WM, Nosten, F, Pereira, DB, Phan, GT, Phyo, AP, Rowland, M, Saravu, K, Sibley, CH, Siqueira, AM, Stepniewska, K, Sutanto, I, Taylor, WRJ, Thwaites, G, Tran, BQ, Tran, HT, Valecha, N, Vieira, JLF, Wangchuk, S, William, T, Woodrow, CJ, Zuluaga-Idarraga, L, Guerin, PJ, White, NJ, Price, RN

Publikováno v: The lancet infectious diseases
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Lancet infectious diseases, 18(9), 1025-1034. Lancet Publishing Group
LANCET INFECTIOUS DISEASES

BACKGROUND\ud Chloroquine remains the mainstay of treatment for Plasmodium vivax malaria despite increasing reports of treatment failure. We did a systematic review and meta-analysis to investigate the effect of chloroquine dose and the addition of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6285fd24b995109d72a07545c3cadd0c
https://hdl.handle.net/10067/1536920151162165141

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

Autor: Mok, S, Ashley, EA, Ferreira, PE, Zhu, L, Lin, Z, Yeo, T, Chotivanich, K, Imwong, M, Pukrittayakamee, S, Dhorda, M, Nguon, C, Lim, P, Amaratunga, C, Suon, S, Hien, TT, Htut, Y, Faiz, MA, Onyamboko, MA, Mayxay, M, Newton, PN, Tripura, R, Woodrow, CJ, Miotto, O, Kwiatkowski, DP, Nosten, F, Day, NP, Preiser, PR, White, NJ, Dondorp, AM, Fairhurst, RM, Bozdech, Z

Publikováno v: Science (New York, N.Y.). 347(6220)

Artemisinin resistance in Plasmodium falciparum threatens global efforts to control and eliminate malaria. Polymorphisms in the kelch domain-carrying protein K13 are associated with artemisinin resistance, but the underlying molecular mechanisms are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::d7d6d9ffe96b677256479ea2b876d31e
http://ora.ox.ac.uk/objects/uuid:54f8cdb6-8fdf-4f5a-b32b-2cb0b74b7bd9

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