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The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis.

Autor: Park JM; Department of Surgery, University of Iowa, Iowa City, IA, USA.; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA., Wu T; Department of Surgery, University of Iowa, Iowa City, IA, USA., Cyr AR; Department of Surgery, University of Iowa, Iowa City, IA, USA., Woodfield GW; Department of Surgery, University of Iowa, Iowa City, IA, USA., De Andrade JP; Department of Surgery, University of Iowa, Iowa City, IA, USA., Spanheimer PM; Department of Surgery, University of Iowa, Iowa City, IA, USA., Li T; The Genome Institute, Washington University, Saint Louis, MO, USA., Sugg SL; Department of Surgery, University of Iowa, Iowa City, IA, USA., Lal G; Department of Surgery, University of Iowa, Iowa City, IA, USA., Domann FE; Department of Surgery, University of Iowa, Iowa City, IA, USA.; Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA.; Department of Pathology, University of Iowa, Iowa City, IA, USA., Zhang W; Department of Pathology, University of Iowa, Iowa City, IA, USA., Weigel RJ; Department of Surgery, University of Iowa, Iowa City, IA, USA.; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA.; Department of Biochemistry, University of Iowa, Iowa City, IA, USA.

Publikováno v: Oncogene [Oncogene] 2015 Dec 10; Vol. 34 (50), pp. 6105-14. Date of Electronic Publication: 2015 Mar 16.

TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis.

Autor: Cyr AR; 1] Department of Surgery, University of Iowa, Iowa City, IA, USA [2] Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA., Kulak MV; Department of Surgery, University of Iowa, Iowa City, IA, USA., Park JM; Department of Surgery, University of Iowa, Iowa City, IA, USA., Bogachek MV; Department of Surgery, University of Iowa, Iowa City, IA, USA., Spanheimer PM; Department of Surgery, University of Iowa, Iowa City, IA, USA., Woodfield GW; Department of Surgery, University of Iowa, Iowa City, IA, USA., White-Baer LS; Department of Surgery, University of Iowa, Iowa City, IA, USA., O'Malley YQ; Department of Surgery, University of Iowa, Iowa City, IA, USA., Sugg SL; Department of Surgery, University of Iowa, Iowa City, IA, USA., Olivier AK; Department of Pathology, University of Iowa, Iowa City, IA, USA., Zhang W; Department of Pathology, University of Iowa, Iowa City, IA, USA., Domann FE; 1] Department of Surgery, University of Iowa, Iowa City, IA, USA [2] Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA [3] Department of Pathology, University of Iowa, Iowa City, IA, USA., Weigel RJ; 1] Department of Surgery, University of Iowa, Iowa City, IA, USA [2] Department of Biochemistry, University of Iowa, Iowa City, IA, USA.

Publikováno v: Oncogene [Oncogene] 2015 Jan 22; Vol. 34 (4), pp. 436-44. Date of Electronic Publication: 2014 Jan 27.

Inhibition of RET increases the efficacy of antiestrogen and is a novel treatment strategy for luminal breast cancer.

Autor: Spanheimer PM; Authors' Affiliations: Departments of Surgery, Pathology, Internal Medicine, and Biochemistry, University of Iowa, Iowa City, Iowa., Park JM, Askeland RW, Kulak MV, Woodfield GW, De Andrade JP, Cyr AR, Sugg SL, Thomas A, Weigel RJ

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2014 Apr 15; Vol. 20 (8), pp. 2115-25. Date of Electronic Publication: 2014 Feb 13.

Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer.

Autor: Kulak MV; Department of Surgery, University of Iowa, Iowa City, IA 52242-1086, USA., Cyr AR, Woodfield GW, Bogachek M, Spanheimer PM, Li T, Price DH, Domann FE, Weigel RJ

Publikováno v: Oncogene [Oncogene] 2013 Aug 22; Vol. 32 (34), pp. 4043-51. Date of Electronic Publication: 2012 Sep 10.