Zobrazeno 1 - 10
of 579
pro vyhledávání: '"Wood, KJ"'
Publikováno v:
Nature Communications. 13
Regulatory B cells (Breg) are a heterogenous population with immune-modulating functions. The rarity of human IL-10+ Breg makes translational studies difficult. Here we report ex vivo expansion of human B cells with in vivo regulatory function (expBr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d30f46479af1ad778a3415eda75dfc3
https://doi.org/10.1038/s41467-022-30613-z
https://doi.org/10.1038/s41467-022-30613-z
Regulatory T cell (Treg) therapy is a promising strategy to induce transplant tolerance and may permit a reduction of IS chemotherapy and its toxic side effects. The ONE study clinical trial is currently examining Treg cell therapy in combination wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::d2586a46f349efafafdf9e66a7b84d4f
https://doi.org/10.1097/01.tp.0000490147.72544.1a
https://doi.org/10.1097/01.tp.0000490147.72544.1a
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
Oncoimmunology
Oncoimmunology
Three recent publications identified the TNF/TNR2 pathway as a new target to reduce graft-versus-host-disease through regulatory T cells activation or to potentially switch on a strong anti-leukemic effect through regulatory T cells blockade in allog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::516d252443a37b6dc63caa753147791c
https://ora.ox.ac.uk/objects/uuid:b57eac31-a8d1-4a9f-830e-41d42fe9ce57
https://ora.ox.ac.uk/objects/uuid:b57eac31-a8d1-4a9f-830e-41d42fe9ce57
Autor:
Ensminger, SM, Spriewald, BM, Witzke, O, Morrison, K, Pajaro, OE, Morris, PJ, Rose, ML, Wood, KJ
INTRODUCTION: Transplant arteriosclerosis is still the major complication for long-term allograft survival in clinical transplantation. The aim of our study was to investigate the impact of MHC disparity on the kinetics of the development of transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ec1c3a7a0714f9bf0f093955dca99543
https://doi.org/10.1097/00007890-200204150-00009
https://doi.org/10.1097/00007890-200204150-00009
Autor:
Gilot, BJ, Hara, M, Jones, ND, van Maurik, A, Niimi, M, Hadjianastassiou, V, Morris, PJ, Wood, KJ
BACKGROUND: An adoptive transfer system was used to study the fate of alloreactive CD8+ H-2Kb-specific TCR transgenic (DES+) T cells in vivo after transplantation. METHODS: A trace population of 2.0x10(6) CD8+DES+ T cells were adoptively transferred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::87878fbe0b290c4306fdf24f71011f04
https://doi.org/10.1097/00007890-200002270-00028
https://doi.org/10.1097/00007890-200002270-00028
Exposure to alloantigen in vivo or in vitro induces alloantigen reactive regulatory T cells that can control transplant rejection. The mechanisms that underpin the activity of alloantigen reactive regulatory T cells in vivo are common with those of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2ae9aa579199bdecc3ad3d488b1fddd0
https://doi.org/10.1111/j.1600-065x.2011.01013.x
https://doi.org/10.1111/j.1600-065x.2011.01013.x
BACKGROUND: The beneficial effect on graft survival achieved by pretransplant blood transfusions is well established. Previous studies have shown that the degree of major histocompatibility complex (MHC) (mis)-match between the transfusion donor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3e2e3ac480516aae01e8c9b4afc9f561
https://ora.ox.ac.uk/objects/uuid:e1ab8f9c-f4e1-40f3-9e4b-eca345eee2dc
https://ora.ox.ac.uk/objects/uuid:e1ab8f9c-f4e1-40f3-9e4b-eca345eee2dc