Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Woo-Keun Kim"'
Autor:
Ha-Na Oh, Woo-Keun Kim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Previous studies on copper pyrithione (CPT) and zinc pyrithione (ZPT) as antifouling agents have mainly focused on marine organisms. Even though CPT and ZPT pose a risk of human exposure, their neurotoxic effects remain to be elucidated. The
Externí odkaz:
https://doaj.org/article/c5743a26bfdf4670a40e2503a65045ad
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 269, Iss , Pp 115912- (2024)
In this study, we established a coculture model comprising human neuroblastoma SH-SY5Y cells and induced pluripotent stem cell-derived astrocytes, faithfully replicating the human brain environment for in vitro neurotoxicity assessment. We optimized
Externí odkaz:
https://doaj.org/article/42394292f5aa40bb9869f609dc66db8d
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 268, Iss , Pp 115670- (2023)
Parabens can potentially disrupt the hormonal regulation of energy metabolism, leading to issues related to obesity, metabolic health, and the cardiovascular and nervous systems. However, the health effects of parabens have yielded conflicting resear
Externí odkaz:
https://doaj.org/article/264d2d7ee7454306952551992ba283af
Autor:
Sangwoo Lee, Gun Tae Jung, Mina Cho, Jae Won Lee, Kojo Eghan, Jieon Lee, Seokjoo Yoon, Kwang Pyo Kim, Woo-Keun Kim
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 262, Iss , Pp 115119- (2023)
Eicosanoids play important roles in inflammation, allergy, fever, and immune responses. In the eicosanoid pathway, cyclooxygenase (COX) catalyzes the conversion of arachidonic acid to prostaglandins and is a crucial target of nonsteroidal anti-inflam
Externí odkaz:
https://doaj.org/article/918844e64ad14671a7ce25236c93c7ac
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 242, Iss , Pp 113891- (2022)
The genotoxicity, development toxicity, carcinogenicity, and acute or chronic toxic effects of glutaraldehyde (GA), particularly during occupational exposure through its use as a fixative, disinfectant, and preservative, are well-documented but its e
Externí odkaz:
https://doaj.org/article/4bf6b3eb1f7640c2bc9ced48e6476dcf
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 242, Iss , Pp 113923- (2022)
Acrylamide has neurotoxic and/or cardiotoxic effects on humans however available information regarding the neuro- and cardiotoxicity currently is very limited for freshwater organism models. Using three distinct techniques, thus, we investigated the
Externí odkaz:
https://doaj.org/article/86c7f9eb5f494641ba0019d99ffb8434
Autor:
Ah-Won Kwak, Woo-Keun Kim, Seung-On Lee, Goo Yoon, Seung-Sik Cho, Ki-Taek Kim, Mee-Hyun Lee, Yung Hyun Choi, Jin-Young Lee, Jin Woo Park, Jung-Hyun Shim
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 656 (2023)
Licochalcone B (LCB) exhibits anticancer activity in oral cancer, lung cancer, and hepatocellular carcinoma cells. However, little is known about its antitumor mechanisms in human oxaliplatin-sensitive and -resistant colorectal cancer (CRC) cells. Th
Externí odkaz:
https://doaj.org/article/a56a8526697e40c381c5a7ebf3af35ba
Autor:
Sangwoo Lee, Cheolmin Kim, Xiaoshan Liu, Saeram Lee, Younglim Kho, Woo-Keun Kim, Pilje Kim, Kyungho Choi
Publikováno v:
Toxics, Vol 9, Iss 8, p 196 (2021)
Veterinary pharmaceuticals may cause unexpected adverse effects on non-target aquatic species. While these pharmaceuticals were previously identified as priority compounds in ambient water, their ecological risks are relatively unknown. In this study
Externí odkaz:
https://doaj.org/article/a2e6f8b9b17843a0a41350d05bb91b7b
Autor:
Chaewon Jin, Hyeonseok Jin, Byung-Cheon Jeong, Dong-Hyung Cho, Hang-Suk Chun, Woo-Keun Kim, Jeong Ho Chang
Publikováno v:
Crystals, Vol 11, Iss 5, p 499 (2021)
The nitrilase superfamily, including 13 branches, plays various biological functions in signaling molecule synthesis, vitamin metabolism, small-molecule detoxification, and posttranslational modifications. Most of the mammals and yeasts have Nit1 and
Externí odkaz:
https://doaj.org/article/531991c0b1be42d983f85f84c0fda5a5
Autor:
Jong-Su Park, Palas Samanta, Sangwoo Lee, Jieon Lee, Jae-Woo Cho, Hang-Suk Chun, Seokjoo Yoon, Woo-Keun Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3518 (2021)
Acrylamide is a commonly used industrial chemical that is known to be neurotoxic to mammals. However, its developmental toxicity is rarely assessed in mammalian models because of the cost and complexity involved. We used zebrafish to assess the neuro
Externí odkaz:
https://doaj.org/article/d20eee15d86a468e94adc824be5b72bf