Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Woo Suk Jang"'
Publikováno v:
Journal of Pharmaceutical Investigation. 49:17-26
The well-known anticancer agent, paclitaxel, is a naturally occurring diterpenoid from Taxus brevifolia. It is an effective antineoplastic agent that has been widely used for the treatment of various cancers, including breast, ovarian, and lung cance
Autor:
Joon-Kyung Lee, Woo-Suk Jang, Jeong-Sook Park, Sang-Eun Lee, Jin-Seok Choi, Amolnat Tunsirikongkon, Tae-Hyeon Kim
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 508:294-300
The purpose of this study was to improve the physicochemical properties of solid lipid nanoparticles (SLNs) by modified solvent-evaporation methods. Stearylamine, Tween 80, egg phosphatidylcholine, and docetaxel were used to prepare SLNs. In the conv
Publikováno v:
Journal of Pharmaceutical Investigation. 46:487-493
The objective of this study was to prepare ketoprofen-loaded emulsions. The emulsions were formulated by mixing soybean oil, surfactants (a mixture of Tween 20 and Tween 80), and distilled water. To determine the most suitable composition for the emu
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 92
Surfaces of nanoparticles with are commonly modified to enhance the targeting effect. In this study, we performed surface modifications of docetaxel (DTX)-loaded poly(lactic-co-glycolic acid) nanoparticles (PNPs) with Herceptin® (HCT) to improve the
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 90
The aim of this study was to develop a dutasteride (DUT) solid dispersion (SD) using hydrophilic substances to enhance its dissolution (%) and oral bioavailability in rats. DUT-SD formulations were prepared with various co-polymers using a solvent ev
Autor:
Woo Suk Jang, Hyeong Mo Jeong, Jeong-Sook Park, Soon-Hyung Kwon, Sang-Eun Lee, Jin-Seok Choi, Jong Chan Byeon
Publikováno v:
International journal of pharmaceutics. 526(1-2)
The purpose of this study is to improve the solubility, in vitro dissolution, and oral bioavailability in rats of tadalafil (TDF) by using SD technique with a weak acid and a copolymer. TDF-SD was prepared via solvent evaporation, coupled with the in
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 106
Here, solid dispersion (SD) techniques were utilized to improve the oral bioavailability of tadalafil (TDF). Poly(vinyl pyrrolidone-covinyl acetate) (PVP/VA S-630; 60% VP and 40% VA; MW 50,000) SD formulations were previously found to improve the sol
Publikováno v:
Journal of Korean Society of Rural Planning. 19:73-79
Autor:
Woo Suk Jang, Jin-Ki Kim, Jin-Seok Choi, Young Ho Kim, Choon Lian Ng, Tae-Hyeon Kim, Jeong-Sook Park, Sang-Eun Lee, Joon-Kyung Lee
Publikováno v:
International journal of pharmaceutics. 512(1)
We investigated how to overcome problems associated with the solubility, dissolution, and oral bioavailability of the poorly water-soluble drug compound, chrysosplenol C (CRSP), as well as the effects of single and binary hydrophilic polymers (PVP K-