Phylogenetic ctDNA analysis depicts early stage lung cancer evolution

Autor: Abbosh, C, Birkbak, NJ, Wilson, GA, Jamal-Hanjani, M, Constantin, T, Salari, R, Quesne, JL, Moore, DA, Veeriah, S, Rosenthal, R, Marafioti, T, Kirkizlar, E, Watkins, TBK, McGranahan, N, Ward, S, Martinson, L, Riley, J, Fraioli, F, Bakir, MA, GrÖnroos, E, Zambrana, F, Endozo, R, Bi, WL, Fennessy, FM, Sponer, N, Johnson, D, Laycock, J, Shafi, S, Czyzewska-Khan, J, Rowan, A, Chambers, T, Matthews, N, Turajlic, S, Hiley, C, Lee, SM, Forster, MD, Ahmad, T, Falzon, M, Borg, E, Lawrence, D, Hayward, M, Kolvekar, S, Panagiotopoulos, N, Janes, SM, Thakrar, R, Ahmed, A, Blackhall, F, Summers, Y, Hafez, D, Naik, A, Ganguly, A, Kareht, S, Shah, R, Joseph, L, Quinn, AM, Crosbie, P, Naidu, B, Middleton, G, Langman, G, Trotter, S, Nicolson, M, Remmen, H, Kerr, K, Chetty, M, Gomersall, L, Fennell, DA, Nakas, A, Rathinam, S, Anand, G, Khan, S, Russell, P, Ezhil, V, Ismail, B, Irvin-sellers, M, Prakash, V, Lester, JF, Kornaszewska, M, Attanoos, R, Adams, H, Davies, H, Oukrif, D, Akarca, AU, Hartley, JA, Lowe, HL, Lock, S, Iles, N, Bell, H, Ngai, Y, Elgar, G, Szallasi, Z, Schwarz, RF, Herrero, J, Stewart, A, Quezada, SA, Van Loo, P, Dive, C, Lin, CJ, Rabinowitz, M, Aerts, HJWL, Hackshaw, A, Shaw, JA, Zimmermann, BG, Swanton, C, Bosshard-Carter, L, Goh, G, Gorman, P, Murugaesu, N, Hynds, RE, Wilson, G, Horswell, S, Al Bakir, M, Mitter, R, Escudero, M, Xu, H, Goldman, J, Stone, RK, Denner, T, Biggs, J, Costa, M, Begum, S, Phillimore, B, Nye, E, Graca, S, Joshi, K, Furness, A, Aissa, AB, Wong, YNS, Georgiou, A, Quezada, S, Simeon, C, Hector, G, Smith, A, Aranda, M, Novelli, M, Forster, M, Papadatos-Pastos, D, Carnell, D, Mendes, R, George, J, Navani, N, Taylor, M, Choudhary, J, Califano, R, Taylor, P, Krysiak, P, Rammohan, K, Fontaine, E, Booton, R, Evison, M, Moss, S, Idries, F, Bishop, P, Chaturved, A, Marie Quinn, A, Doran, H, leek, A, Harrison, P, Moore, K, Waddington, R, Novasio, J, Rogan, J, Smith, E, Tugwood, J, Brady, G, Rothwell, DG, Chemi, F, Pierce, J, Gulati, S, Bellamy, M, Bancroft, H, Kerr, A, Kadiri, S, Webb, J, Djearaman, M, Fennell, D, Le Quesne, J, Moore, D, Thomas, A, Walter, H, Monteiro, W, Marshall, H, Nelson, L, Bennett, J, Primrose, L, Amadi, A, Palmer, S, Miller, J, Buchan, K, Lester, J, Edwards, A, Morgan, F, Verjee, A, MacKenzie, M, Wilcox, M, Smith, S, Gower, N, Ottensmeier, C, Chee, S, Johnson, B, Alzetani, A, Shaw, E, Lim, E, De Sousa, P, Tavares Barbosa, M, Bowman, A, Jordan, S, Rice, A, Raubenheimer, H, Proli, C, Elena Cufari, M, Ronquillo, JC, Kwayie, A, Bhayani, H, Hamilton, M, Bakar, Y, Mensah, N, Ambrose, L, Devaraj, A, Buderi, S, Finch, J, Azcarate, L, Chavan, H, Green, S, Mashinga, H, Nicholson, AG, Lau, K, Sheaff, M, Schmid, P, Conibear, J, Light, T, Horey, T, Danson, S, Bury, J, Edwards, J, Hill, J, Matthews, S, Kitsanta, Y, Suvarna, K, Fisher, P, Keerio, AD, Shackcloth, M, Gosney, J, Postmus, P, Feeney, S, Asante-Siaw, J, Constatin, T, Zimmermann, B, Dentro, S, Dessimoz, C, Shiu, K-K, Bridgewater, J, Hochauser, D, Beck, S, Parker, P, Walczak, H, Enver, T, Proctor, I, Sinclair, R, Lok, C-W, Mitchison, M, Trevisan, G, Lynch, M, Brandner, S, Gishen, F, Tookman, A, Stone, P, Sterling, C, Larkin, J, Attard, G, Eeles, R, Foster, C, Bova, S, Sottoriva, A, Chowdhury, S, Ashish, C, Spicer, J, Stares, M, Lynch, J, Caldas, C, Brenton, J, Fitzgerald, R, Jimenez-Linan, M, Provenzano, E, Cluroe, A, Stewart, G, Watts, C, Gilbertson, R, McDermott, U, Tavare, S, Maughan, T, Tomlinson, I, Campbell, P, McNeish, I, Biankin, A, Chambers, A, Fraser, S, Oien, K, Krebs, M, Marais, R, Carter, L, Nonaka, D, Dhomen, N, Shaw, J, Baijal, S, Tanchel, B, Collard, M, Cockcroft, P, Taylor, J, Colloby, P, Olisemeke, B, Wilson, R, Harrison, D, Loda, M, Flanagan, A, McKenzie, M, Lederman, J, Sharp, A, Farrelly, L

Publikováno v: Nature, vol. 545, no. 7655, pp. 446-451

The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed metastatic sites, might offer new therapeutic approaches for limiting tumour recurrence. The ability to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488928e0797fc6a75de4915f82e9cf29
https://orca.cardiff.ac.uk/id/eprint/100264/1/nature22364.pdf

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Autor: Nicholas McGranahan, Rachel Rosenthal, Crispin T. Hiley, Andrew J. Rowan, Thomas B.K. Watkins, Gareth A. Wilson, Nicolai J. Birkbak, Selvaraju Veeriah, Peter Van Loo, Javier Herrero, Charles Swanton, Mariam Jamal-Hanjani, Seema Shafi, Justyna Czyzewska-Khan, Diana Johnson, Joanne Laycock, Leticia Bosshard-Carter, Pat Gorman, Robert E. Hynds, Gareth Wilson, Stuart Horswell, Richard Mitter, Mickael Escudero, Aengus Stewart, Andrew Rowan, Hang Xu, Samra Turajlic, Crispin Hiley, Christopher Abbosh, Jacki Goldman, Richard Kevin Stone, Tamara Denner, Nik Matthews, Greg Elgar, Sophia Ward, Marta Costa, Sharmin Begum, Ben Phillimore, Tim Chambers, Emma Nye, Sofia Graca, Maise Al Bakir, Kroopa Joshi, Andrew Furness, Assma Ben Aissa, Yien Ning Sophia Wong, Andy Georgiou, Sergio Quezada, John A. Hartley, Helen L. Lowe, David Lawrence, Martin Hayward, Nikolaos Panagiotopoulos, Shyam Kolvekar, Mary Falzon, Elaine Borg, Teresa Marafioti, Celia Simeon, Gemma Hector, Amy Smith, Marie Aranda, Marco Novelli, Dahmane Oukrif, Sam M. Janes, Ricky Thakrar, Martin Forster, Tanya Ahmad, Siow Ming Lee, Dionysis Papadatos-Pastos, Dawn Carnell, Ruheena Mendes, Jeremy George, Neal Navani, Asia Ahmed, Magali Taylor, Junaid Choudhary, Yvonne Summers, Raffaele Califano, Paul Taylor, Rajesh Shah, Piotr Krysiak, Kendadai Rammohan, Eustace Fontaine, Richard Booton, Matthew Evison, Phil Crosbie, Stuart Moss, Faiza Idries, Leena Joseph, Paul Bishop, Anshuman Chaturved, Anne Marie Quinn, Helen Doran, Angela Leek, Phil Harrison, Katrina Moore, Rachael Waddington, Juliette Novasio, Fiona Blackhall, Jane Rogan, Elaine Smith, Caroline Dive, Jonathan Tugwood, Ged Brady, Dominic G. Rothwell, Francesca Chemi, Jackie Pierce, Sakshi Gulati, Babu Naidu, Gerald Langman, Simon Trotter, Mary Bellamy, Hollie Bancroft, Amy Kerr, Salma Kadiri, Joanne Webb, Gary Middleton, Madava Djearaman, Dean Fennell, Jacqui A. Shaw, John Le Quesne, David Moore, Apostolos Nakas, Sridhar Rathinam, William Monteiro, Hilary Marshall, Louise Nelson, Jonathan Bennett, Joan Riley, Lindsay Primrose, Luke Martinson, Girija Anand, Sajid Khan, Anita Amadi, Marianne Nicolson, Keith Kerr, Shirley Palmer, Hardy Remmen, Joy Miller, Keith Buchan, Mahendran Chetty, Lesley Gomersall, Jason Lester, Alison Edwards, Fiona Morgan, Haydn Adams, Helen Davies, Malgorzata Kornaszewska, Richard Attanoos, Sara Lock, Azmina Verjee, Mairead MacKenzie, Maggie Wilcox, Harriet Bell, Allan Hackshaw, Yenting Ngai, Sean Smith, Nicole Gower, Christian Ottensmeier, Serena Chee, Benjamin Johnson, Aiman Alzetani, Emily Shaw, Eric Lim, Paulo De Sousa, Monica Tavares Barbosa, Alex Bowman, Simon Jordan, Alexandra Rice, Hilgardt Raubenheimer, Chiara Proli, Maria Elena Cufari, John Carlo Ronquillo, Angela Kwayie, Harshil Bhayani, Morag Hamilton, Yusura Bakar, Natalie Mensah, Lyn Ambrose, Anand Devaraj, Silviu Buderi, Jonathan Finch, Leire Azcarate, Hema Chavan, Sophie Green, Hillaria Mashinga, Andrew G. Nicholson, Kelvin Lau, Michael Sheaff, Peter Schmid, John Conibear, Veni Ezhil, Babikir Ismail, Melanie Irvin-sellers, Vineet Prakash, Peter Russell, Teresa Light, Tracey Horey, Sarah Danson, Jonathan Bury, John Edwards, Jennifer Hill, Sue Matthews, Yota Kitsanta, Kim Suvarna, Patricia Fisher, Allah Dino Keerio, Michael Shackcloth, John Gosney, Pieter Postmus, Sarah Feeney, Julius Asante-Siaw, Hugo J.W.L. Aerts, Stefan Dentro, Christophe Dessimoz

Publikováno v: McGranahan, N, Rosenthal, R, Hiley, CT, Rowan, AJ, Watkins, TBK, Wilson, GA, Birkbak, NJ, Veeriah, S, Van Loo, P, Herrero, J, Swanton, C, Blackhall, F & Crosbie, P 2017, ' Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution ', Cell . https://doi.org/10.1016/j.cell.2017.10.001
Cell, vol. 171, no. 6, pp. 1259-1271.e11
McGranahan, N, Rosenthal, R, Hiley, C T, Rowan, A J, Watkins, T B K, Wilson, G A, Birkbak, N J, Veeriah, S, Van Loo, P, Herrero, J, Swanton, C, Jamal-Hanjani, M, Shafi, S, Czyzewska-Khan, J, Johnson, D, Laycock, J, Bosshard-Carter, L, Gorman, P, Hynds, R E, Wilson, G, Horswell, S, Mitter, R, Escudero, M, Stewart, A, Rowan, A, Xu, H, Turajlic, S, Abbosh, C, Goldman, J, Stone, R K, Denner, T, Matthews, N, Elgar, G, Ward, S, Costa, M, Begum, S, Phillimore, B, Chambers, T, Nye, E, Graca, S, Al Bakir, M, Joshi, K, Furness, A, Ben Aissa, A, Wong, Y N S, Georgiou, A, Quezada, S, Hartley, J A, Lowe, H L, Lawrence, D, Hayward, M, Panagiotopoulos, N, Kolvekar, S, Falzon, M, Borg, E, Marafioti, T, Simeon, C, Hector, G, Smith, A, Aranda, M, Novelli, M, Oukrif, D, Janes, S M, Thakrar, R, Forster, M, Ahmad, T, Lee, S M, Papadatos-Pastos, D, Carnell, D, Mendes, R, George, J, Navani, N, Ahmed, A, Taylor, M, Choudhary, J, Summers, Y, Califano, R, Taylor, P, Shah, R, Krysiak, P, Rammohan, K, Fontaine, E, Booton, R, Evison, M, Crosbie, P, Moss, S, Idries, F, Joseph, L, Bishop, P, Chaturved, A, Quinn, A M, Doran, H, Leek, A, Harrison, P, Moore, K, Waddington, R, Novasio, J, Blackhall, F, Rogan, J, Smith, E, Dive, C, Tugwood, J, Brady, G, Rothwell, D G, Chemi, F, Pierce, J, Gulati, S, Naidu, B, Langman, G, Trotter, S, Bellamy, M, Bancroft, H, Kerr, A, Kadiri, S, Webb, J, Middleton, G, Djearaman, M, Fennell, D, Shaw, J A, Le Quesne, J, Moore, D, Nakas, A, Rathinam, S, Monteiro, W, Marshall, H, Nelson, L, Bennett, J, Riley, J, Primrose, L, Martinson, L, Anand, G, Khan, S, Amadi, A, Nicolson, M, Kerr, K, Palmer, S, Remmen, H, Miller, J, Buchan, K, Chetty, M, Gomersall, L, Lester, J, Edwards, A, Morgan, F, Adams, H, Davies, H, Kornaszewska, M, Attanoos, R, Lock, S, Verjee, A, MacKenzie, M, Wilcox, M, Bell, H, Hackshaw, A, Ngai, Y, Smith, S, Gower, N, Ottensmeier, C, Chee, S, Johnson, B, Alzetani, A, Shaw, E, Lim, E, De Sousa, P, Barbosa, M T, Bowman, A, Jordan, S, Rice, A, Raubenheimer, H, Proli, C, Cufari, M E, Ronquillo, J C, Kwayie, A, Bhayani, H, Hamilton, M, Bakar, Y, Mensah, N, Ambrose, L, Devaraj, A, Buderi, S, Finch, J, Azcarate, L, Chavan, H, Green, S, Mashinga, H, Nicholson, A G, Lau, K, Sheaff, M, Schmid, P, Conibear, J, Ezhil, V, Ismail, B, Irvin-sellers, M, Prakash, V, Russell, P, Light, T, Horey, T, Danson, S, Bury, J, Edwards, J, Hill, J, Matthews, S, Kitsanta, Y, Suvarna, K, Fisher, P, Keerio, A D, Shackcloth, M, Gosney, J, Postmus, P, Feeney, S, Asante-Siaw, J, Aerts, H J W L, Dentro, S & Dessimoz, C 2017, ' Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution ', Cell, vol. 171, no. 6, pp. 1259-1271.e11 . https://doi.org/10.1016/j.cell.2017.10.001

Immune evasion is a hallmark of cancer. Losing the ability to present neoantigens through human leukocyte antigen (HLA) loss may facilitate immune evasion. However, the polymorphic nature of the locus has precluded accurate HLA copy-number analysis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a275b5e6604203ea0560773e9e9dacd
https://research.manchester.ac.uk/en/publications/55c31c82-3f24-435d-bb77-3fb2c6170a8f

Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumors.

Autor: Vesely C; UCL Cancer Institute, UCL, London, United Kingdom., Wong YNS; UCL Cancer Institute, UCL, London, United Kingdom.; Cancer Immunology Unit, Research Department of Hematology, UCL Cancer Institute, UCL, London, United Kingdom., Childs A; UCL Cancer Institute, UCL, London, United Kingdom.; Royal Free Hospital, Pond Street, London, United Kingdom., Akarca AU; UCL Cancer Institute, UCL, London, United Kingdom., Dhami P; UCL Cancer Institute, UCL, London, United Kingdom., Vaikkinen H; UCL Cancer Institute, UCL, London, United Kingdom., Conde L; UCL Cancer Institute, UCL, London, United Kingdom., Herrero J; UCL Cancer Institute, UCL, London, United Kingdom., Ogunbiyi O; Royal Free Hospital, Pond Street, London, United Kingdom., Gander A; Royal Free Hospital, Pond Street, London, United Kingdom., Luong TV; Royal Free Hospital, Pond Street, London, United Kingdom., Thirlwell C; UCL Cancer Institute, UCL, London, United Kingdom.; The University of Exeter Medical School, Exeter, United Kingdom., Caplin M; Royal Free Hospital, Pond Street, London, United Kingdom., Toumpanakis C; Royal Free Hospital, Pond Street, London, United Kingdom., Peggs K; UCL Cancer Institute, UCL, London, United Kingdom.; Cancer Immunology Unit, Research Department of Hematology, UCL Cancer Institute, UCL, London, United Kingdom., Quezada SA; UCL Cancer Institute, UCL, London, United Kingdom.; Cancer Immunology Unit, Research Department of Hematology, UCL Cancer Institute, UCL, London, United Kingdom., Marafioti T; UCL Cancer Institute, UCL, London, United Kingdom., Meyer T; UCL Cancer Institute, UCL, London, United Kingdom.; Royal Free Hospital, Pond Street, London, United Kingdom.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Jun 13; Vol. 28 (12), pp. 2657-2668.

Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective.

Autor: Soosaipillai G; Cancer Division, University College London Hospitals, London, UK., Wu A; Cancer Division, University College London Hospitals, London, UK., Dettorre GM; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Diamantis N; Medical Oncology, Barts Health NHS Trust, London, UK., Chester J; Medical Oncology, School of Medicine, Cardiff University, Cardiff, UK., Moss C; Translational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, UK., Aguilar-Company J; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain., Bower M; Department of Oncology and National Centre for HIV Malignancy, Chelsea & Westminster Hospital, London, UK., Sng CC; Cancer Division, University College London Hospitals, London, UK., Salazar R; Department of Medical Oncology, ICO L'Hospitalet, Oncobell Program (IDIBELL), CIBERONC. Hospitalet de Llobregat, Spain., Brunet J; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Jones E; Medical Oncology, Guy's and St Thomas' NHS Foundation Trust (GSTT), London, UK., Mesia R; Department of Medical Oncology, Catalan Institute of Oncology, Badalona, Spain., Jackson A; Clinical Trials, Velindre Cancer Centre, Cardiff, UK., Mukherjee U; Medical Oncology, Barts Health NHS Trust, London, UK., Sita-Lumsden A; Medical Oncology, Guy's and St Thomas' NHS Foundation Trust (GSTT), London, UK., Seguí E; Department of Medical Oncology, Hospital Clinic, Barcelona, Spain., Ottaviani D; Cancer Division, University College London Hospitals, London, UK., Carbó A; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Benafif S; Cancer Division, University College London Hospitals, London, UK., Würstlein R; Department of Gynaecology and Obstetrics, Breast Centre and Gynaecological Cancer Centre and CCC Munich, University Hospital Munich, Munich, Germany., Carmona C; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Chopra N; Cancer Division, University College London Hospitals, London, UK., Cruz CA; Department of Medical Oncology, Hospital Clinic, Barcelona, Spain., Swallow J; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Saoudi N; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain., Felip E; Department of Medical Oncology, Catalan Institute of Oncology, Badalona, Spain., Galazi M; Cancer Division, University College London Hospitals, London, UK., Garcia-Fructuoso I; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Lee AJX; Cancer Division, University College London Hospitals, London, UK., Newsom-Davis T; Department of Oncology and National Centre for HIV Malignancy, Chelsea & Westminster Hospital, London, UK., Wong YNS; Cancer Division, University College London Hospitals, London, UK., Sureda A; Haematology Department, ICO Hospitalet, Hospitalet de Llobregat, IDIBELL, Universitat de Barcelona, Spain., Maluquer C; Haematology Department, ICO Hospitalet, Hospitalet de Llobregat, IDIBELL, Universitat de Barcelona, Spain., Ruiz-Camps I; Infectious Diseases, Vall d'Hebron University Hospital, Barcelona, Spain., Cabirta A; Department of Haematology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain., Prat A; Department of Medical Oncology, Hospital Clinic, Barcelona, Spain., Loizidou A; Department of Infectious Diseases, Internal Medicine, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium., Gennari A; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale and Maggiore della Carità Hospital, Novara, Italy., Ferrante D; Department of Translational Medicine, Unit of Cancer Epidemiology, CPO-Piemonte, University of Eastern Piedmont, Novara, Italy., Tabernero J; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain., Russell B; Translational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, UK., Van Hemelrijck M; Translational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, UK., Dolly S; Medical Oncology, Guy's and St Thomas' NHS Foundation Trust (GSTT), London, UK., Hulbert-Williams NJ; Professor of Behavioural Medicine, Centre for Contextual Behavioural Science, School of Psychology, University of Chester, Chritchley Building, Parkgate Road, Chester, Cheshire, CH1 4BJ, UK., Pinato DJ; Department of Surgery and Cancer, Clinical Senior Lecturer and Consultant Medical Oncologist, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK.

Publikováno v: Therapeutic advances in medical oncology [Ther Adv Med Oncol] 2021 Sep 02; Vol. 13, pp. 17588359211042224. Date of Electronic Publication: 2021 Sep 02 (Print Publication: 2021).

Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid Inflammatory Score.

Autor: Dettorre GM; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK., Dolly S; Medical Oncology, Guy's and St Thomas' NHS Foundation Trust (GSTT), London, UK., Loizidou A; Department of Infectious Diseases, Internal Medicine, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium., Chester J; Medical Oncology, School of Medicine, Cardiff University, Cardiff, UK.; Medical Oncology, Velindre Cancer Centre, Cardiff, UK., Jackson A; Clinical Trials, Velindre Cancer Centre, Cardiff, UK., Mukherjee U; Medical Oncology, Barts Health NHS Trust, London, UK., Zambelli A; Oncology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy., Aguilar-Company J; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain.; Infectious Diseases, Vall d'Hebron University Hospital, Barcelona, Spain., Bower M; Department of Oncology and National Centre for HIV Malignancy, Chelsea and Westminster Hospital, London, UK., Sng CCT; Cancer Division, University College London Hospitals, London, UK., Salazar R; Department of Medical Oncology, ICO L'Hospitalet, Oncobell Program (IDIBELL), CIBERONC, Hospitalet de Llobregat, Spain., Bertuzzi A; Medical Oncology and Hematology Unit, Humanitas Cancer Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy., Brunet J; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Mesia R; Department of Medical Oncology, Catalan Institute of Oncology, Badalona, Spain., Sita-Lumsden A; Medical Oncology, Guy's and St Thomas' NHS Foundation Trust (GSTT), London, UK., Seguí E; Department of Medical Oncology, Hospital Clinic, Barcelona, Spain., Biello F; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale and Maggiore della Carità Hospital, Novara, Italy., Generali D; Multidisciplinary Breast Pathology and Translational Research Unit, ASST Cremona, Cremona, Italy.; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Grisanti S; Medical Oncology Unit, Spedali Civili, Brescia, Italy., Seeva P; Medical Oncology, Guy's and St Thomas' NHS Foundation Trust (GSTT), London, UK., Rizzo G; Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Libertini M; Medical Oncology Unit, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Maconi A; Infrastruttura Ricerca Formazione Innovazione, Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy., Moss C; Translational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, UK., Russell B; Translational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, UK., Harbeck N; Department of Gynecology and Obstetrics, Breast Center and Gynecological Cancer Center and CCC Munich, University Hospital Munich, Munich, Germany., Vincenzi B; Medical Oncology, Policlinico Universitario Campus Bio-Medico, Rome, Italy., Bertulli R; Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Ottaviani D; Cancer Division, University College London Hospitals, London, UK., Liñan R; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Marrari A; Medical Oncology and Hematology Unit, Humanitas Cancer Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy., Carmona-García MC; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Chopra N; Cancer Division, University College London Hospitals, London, UK., Tondini CA; Oncology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy., Mirallas O; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain., Tovazzi V; Medical Oncology Unit, Spedali Civili, Brescia, Italy., Fotia V; Oncology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy., Cruz CA; Department of Medical Oncology, Hospital Clinic, Barcelona, Spain., Saoudi-Gonzalez N; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain., Felip E; Department of Medical Oncology, Catalan Institute of Oncology, Badalona, Spain., Roqué A; Department of Medical Oncology, Catalan Institute of Oncology, University Hospital Josep Trueta, Girona, Spain., Lee AJX; Cancer Division, University College London Hospitals, London, UK., Newsom-Davis T; Department of Oncology and National Centre for HIV Malignancy, Chelsea and Westminster Hospital, London, UK., García-Illescas D; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain., Reyes R; Department of Medical Oncology, Hospital Clinic, Barcelona, Spain., Wong YNS; Cancer Division, University College London Hospitals, London, UK., Ferrante D; Department of Translational Medicine, Unit of Cancer Epidemiology, CPO-Piemonte, University of Eastern Piedmont, Novara, Italy., Scotti L; Department of Translational Medicine, Unit of Cancer Epidemiology, CPO-Piemonte, University of Eastern Piedmont, Novara, Italy., Marco-Hernández J; Department of Internal Medicine, Hospital Clinic, Barcelona, Spain., Ruiz-Camps I; Infectious Diseases, Vall d'Hebron University Hospital, Barcelona, Spain., Patriarca A; Division of Haematology, Department of Translational Medicine, University of Piemonte Orientale and Maggiore della Carità Hospital, Novara, Italy., Rimassa L; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, 20090 Pieve Emanuele, Milan, Italy., Chiudinelli L; Oncology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy., Franchi M; Oncology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy., Santoro A; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, 20090 Pieve Emanuele, Milan, Italy., Prat A; Translational Genomics and Targeted Therapies in Solid Tumors, IDIBAPS, Barcelona, Spain., Gennari A; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale and Maggiore della Carità Hospital, Novara, Italy., Van Hemelrijck M; Medical Oncology, Guy's and St Thomas' NHS Foundation Trust (GSTT), London, UK.; Translational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, UK., Tabernero J; Medical Oncology, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), IOB-Quiron, UVic-UCC, Barcelona, Spain., Diamantis N; Medical Oncology, Barts Health NHS Trust, London, UK., Pinato DJ; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK david.pinato@imperial.ac.uk.; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale and Maggiore della Carità Hospital, Novara, Italy.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Mar; Vol. 9 (3).