Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors

Autor: Urbani, Luca, Camilli, Carlotta, Phylactopoulos, Demetra-Ellie, Crowley, Claire, Natarajan, Dipa, Scottoni, Federico, Maghsoudlou, Panayiotis, McCann, Conor J., Pellegata, Alessandro Filippo, Urciuolo, Anna, Deguchi, Koichi, Khalaf, Sahira, Aruta, Salvatore Ferdinando, Signorelli, Maria Cristina, Kiely, David, Hannon, Edward, Trevisan, Matteo, Wong, Rui Rachel, Baradez, Marc Olivier, Moulding, Dale, Virasami, Alex, Gjinovci, Asllan, Loukogeorgakis, Stavros, Mantero, Sara, Thapar, Nikhil, Sebire, Neil, Eaton, Simon, Lowdell, Mark, Cossu, Giulio, Bonfanti, Paola, De Coppi, Paolo

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Urbani, L, Camilli, C, Phylactopoulos, D, Crowley, C, Natarajan, D, Scottoni, F, Maghsoudlou, P, Mccann, C J, Pellegata, A F, Urciuolo, A, Deguchi, K, Khalaf, S, Aruta, S F, Signorelli, M C, Kiely, D, Hannon, E, Trevisan, M, Wong, R R, Baradez, M O, Moulding, D, Virasami, A, Gjinovci, A, Loukogeorgakis, S, Mantero, S, Thapar, N, Sebire, N, Eaton, S, Lowdell, M, Cossu, G, Bonfanti, P & De Coppi, P 2018, ' Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors ', Nature Communications, vol. 9, no. 1 . https://doi.org/10.1038/s41467-018-06385-w

A tissue engineered oesophagus could overcome limitations associated with oesophageal substitution. Combining decellularized scaffolds with patient-derived cells shows promise for regeneration of tissue defects. In this proof-of-principle study, a tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::81719f6b1d6a67db873f5da7ef8d314a
https://lirias.kuleuven.be/handle/20.500.12942/692411