Zobrazeno 1 - 10
of 684
pro vyhledávání: '"Wong, Ka Chun"'
One develops a fast computational methodology for principal component analysis on manifolds. Instead of estimating intrinsic principal components on an object space with a Riemannian structure, one embeds the object space in a numerical space, and th
Externí odkaz:
http://arxiv.org/abs/2409.03572
The rapid advancement of single-cell ATAC sequencing (scATAC-seq) technologies holds great promise for investigating the heterogeneity of epigenetic landscapes at the cellular level. The amplification process in scATAC-seq experiments often introduce
Externí odkaz:
http://arxiv.org/abs/2408.14801
Accurate screening of cancer types is crucial for effective cancer detection and precise treatment selection. However, the association between gene expression profiles and tumors is often limited to a small number of biomarker genes. While computatio
Externí odkaz:
http://arxiv.org/abs/2404.04547
Autor:
Huang, Lei, Yuan, Zheng, Yan, Huihui, Sheng, Rong, Liu, Linjing, Wang, Fuzhou, Xie, Weidun, Chen, Nanjun, Huang, Fei, Huang, Songfang, Wong, Ka-Chun, Zhang, Yaoyun
Advances in deep generative models shed light on de novo molecule generation with desired properties. However, molecule generation targeted for dual protein targets still faces formidable challenges including protein 3D structure data requisition for
Externí odkaz:
http://arxiv.org/abs/2306.13957
Molecule generation, especially generating 3D molecular geometries from scratch (i.e., 3D \textit{de novo} generation), has become a fundamental task in drug designs. Existing diffusion-based 3D molecule generation methods could suffer from unsatisfa
Externí odkaz:
http://arxiv.org/abs/2209.05710
Publikováno v:
In Swarm and Evolutionary Computation December 2024 91
Publikováno v:
In Expert Systems With Applications 15 November 2024 254
Publikováno v:
In Knowledge-Based Systems 25 October 2024 302
Recently, many evolutionary computation methods have been developed to solve the feature selection problem. However, the studies focused mainly on small-scale issues, resulting in stagnation issues in local optima and numerical instability when deali
Externí odkaz:
http://arxiv.org/abs/2110.14166