Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wondwossen M. Yeshaw"'
Autor:
Katarzyna Miskiewicz, Liya E. Jose, Wondwossen M. Yeshaw, Jorge S. Valadas, Jef Swerts, Sebastian Munck, Fabian Feiguin, Bart Dermaut, Patrik Verstreken
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 94-102 (2014)
Presynaptic densities are specialized structures involved in synaptic vesicle tethering and neurotransmission; however, the mechanisms regulating their function remain understudied. In Drosophila, Bruchpilot is a major constituent of the presynaptic
Externí odkaz:
https://doaj.org/article/6538ed6ade044d899b33f4f541929ebe
Autor:
Herschel S Dhekne, Francesca Tonelli, Wondwossen M Yeshaw, Claire Y Chiang, Charles Limouse, Ebsy Jaimon, Elena Purlyte, Dario R Alessi, Suzanne R Pfeffer
Publikováno v:
eLife, Vol 12 (2023)
Activating mutations in the leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease. LRRK2 phosphorylates a subset of Rab GTPases, particularly Rab10 and Rab8A, and we showed previously that these phosphoRabs play an important role in LRRK2
Externí odkaz:
https://doaj.org/article/3565c7f6dcf745449d8d8cc68bd1cf97
Autor:
Kerryn Berndsen, Pawel Lis, Wondwossen M Yeshaw, Paulina S Wawro, Raja S Nirujogi, Melanie Wightman, Thomas Macartney, Mark Dorward, Axel Knebel, Francesca Tonelli, Suzanne R Pfeffer, Dario R Alessi
Publikováno v:
eLife, Vol 8 (2019)
Mutations that activate LRRK2 protein kinase cause Parkinson’s disease. LRRK2 phosphorylates a subset of Rab GTPases within their Switch-II motif controlling interaction with effectors. An siRNA screen of all human protein phosphatases revealed tha
Externí odkaz:
https://doaj.org/article/6a5369c02adb4cf08a138e9a247156ed
Autor:
Wondwossen M Yeshaw, Marianne van der Zwaag, Francesco Pinto, Liza L Lahaye, Anita IE Faber, Rubén Gómez-Sánchez, Amalia M Dolga, Conor Poland, Anthony P Monaco, Sven CD van IJzendoorn, Nicola A Grzeschik, Antonio Velayos-Baeza, Ody CM Sibon
Publikováno v:
eLife, Vol 8 (2019)
The VPS13A gene is associated with the neurodegenerative disorder Chorea Acanthocytosis. It is unknown what the consequences are of impaired function of VPS13A at the subcellular level. We demonstrate that VPS13A is a peripheral membrane protein, ass
Externí odkaz:
https://doaj.org/article/82c95e0d7eb64c9cabeaa87ffdcdcbf4
Autor:
Herschel S. Dhekne, Francesca Tonelli, Wondwossen M. Yeshaw, Claire Y. Chiang, Charles Limouse, Ebsy Jaimon, Elena Purlyte, Dario R. Alessi, Suzanne R. Pfeffer
Activating mutations in the Leucine Rich Repeat Kinase 2 (LRRK2) cause Parkinson’s disease. LRRK2 phosphorylates a subset of Rab GTPases, particularly Rab10 and Rab8A, and we showed previously that phosphoRabs play an important role in LRRK2 membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3257f216220943444e2beacd3afcc126
https://doi.org/10.1101/2023.02.17.529028
https://doi.org/10.1101/2023.02.17.529028
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Mutations that activate LRRK2 protein kinase cause Parkinson's disease. LRRK2 phosphorylates a subset of Rab GTPases, in particular Rab8 and Rab10. We show here details related to the mechanism by which Rab10 phosphorylation blocks initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79da4002b1a01cea62a1955c17a664bd
https://doi.org/10.1073/pnas.2005894118
https://doi.org/10.1073/pnas.2005894118
Autor:
Axel Knebel, Francesca Tonelli, Thomas Macartney, Raja Sekhar Nirujogi, Mark Dorward, Wondwossen M Yeshaw, Kerryn Berndsen, Melanie Wightman, Dario R. Alessi, Pawel Lis, Suzanne R. Pfeffer, Paulina S. Wawro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6089846f324ee2b84d0af7decbd6c973
https://doi.org/10.7554/elife.50416.039
https://doi.org/10.7554/elife.50416.039
Autor:
Pawel Lis, Suzanne R. Pfeffer, Mark Dorward, Wondwossen M Yeshaw, Axel Knebel, Dario R. Alessi, Melanie Wightman, Francesca Tonelli, Raja Sekhar Nirujogi, Paulina S. Wawro, Thomas Macartney, Kerryn Berndsen
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Mutations that activate LRRK2 protein kinase cause Parkinson’s disease. LRRK2 phosphorylates a subset of Rab GTPases within their Switch-II motif controlling interaction with effectors. An siRNA screen of all protein phosphatases revealed that a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1db5840a4d01cdfea510f592a200790
Autor:
Antonio Velayos-Baeza, Conor Poland, Amalia M. Dolga, Rubén Gómez-Sánchez, Anita I. E. Faber, Nicola A. Grzeschik, Anthony P. Monaco, Francesco Pinto, Ody C. M. Sibon, Wondwossen M Yeshaw, Liza L. Lahaye, Sven C.D. van IJzendoorn, Marianne van der Zwaag
Publikováno v:
eLife, 8:43561. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 8 (2019)
eLife
eLife, Vol 8 (2019)
eLife
The VPS13A gene is associated with the neurodegenerative disorder Chorea Acanthocytosis. It is unknown what the consequences are of impaired function of VPS13A at the subcellular level. We demonstrate that VPS13A is a peripheral membrane protein, ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7e32d594a9211f0604d270810eeb77
https://doi.org/10.7554/elife.43561
https://doi.org/10.7554/elife.43561
Autor:
Anita I. E. Faber, Nicola A. Grzeschik, Marianne van der Zwaag, Antonio Velayos-Baeza, Rubén Gómez-Sánchez, Liza L. Lahaye, Conor Poland, Ody C. M. Sibon, Francesco Pinto, Amalia M. Dolga, Wondwossen M Yeshaw, Anthony P. Monaco, Sven C.D. van IJzendoorn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f078ade2d7ec988c1052dfb902adde5
https://doi.org/10.7554/elife.43561.038
https://doi.org/10.7554/elife.43561.038