Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3.

Autor: Tsepo Lebiletsa Tsekoa, Therese Lotter-Stark, Sindisiwe Buthelezi, Ereck Chakauya, Stoyan H Stoychev, Claude Sabeta, Wonderful Shumba, Baby Phahladira, Steve Hume, Josh Morton, Charles E Rupprecht, Herta Steinkellner, Michael Pauly, Larry Zeitlin, Kevin Whaley, Rachel Chikwamba

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159313 (2016)

Rabies is a neglected zoonotic disease that has no effective treatment after onset of illness. However the disease can be prevented effectively by prompt administration of post exposure prophylaxis which includes administration of passive immunizing

Externí odkaz: https://doaj.org/article/15078b4d36a44f1c8c99a86de7f30e3c

Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3

Autor: Baby Phahladira, Charles E. Rupprecht, Herta Steinkellner, Michael H. Pauly, Tsepo L. Tsekoa, Steve Hume, Claude T. Sabeta, Josh Morton, Larry Zeitlin, Kevin J. Whaley, Ereck Chakauya, Wonderful Shumba, Stoyan Stoychev, Therese Lotter-Stark, Rachel Chikwamba, Sindisiwe G. Buthelezi

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159313 (2016)
PLoS ONE

Rabies is a neglected zoonotic disease that has no effective treatment after onset of illness. However the disease can be prevented effectively by prompt administration of post exposure prophylaxis which includes administration of passive immunizing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468b27a532cde3c99cff676cfa3d4f13
http://europepmc.org/articles/PMC4948892?pdf=render

Engineering, expression in transgenic plants and characterisation of E559, a rabies virus-neutralising monoclonal antibody

Autor: Craig J, van Dolleweerd, Audrey Y-H, Teh, Ashley C, Banyard, Leonard, Both, Hester C T, Lotter-Stark, Tsepo, Tsekoa, Baby, Phahladira, Wonderful, Shumba, Ereck, Chakauya, Claude T, Sabeta, Clemens, Gruber, Anthony R, Fooks, Rachel K, Chikwamba, Julian K-C, Ma

Publikováno v: The Journal of Infectious Diseases

Rabies post-exposure prophylaxis (PEP) currently comprises administration of rabies vaccine together with rabies immunoglobulin (RIG) of either equine or human origin. In the developing world, RIG preparations are expensive, often in short supply, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a69769be5a27276b77643cb271935859
https://pubmed.ncbi.nlm.nih.gov/24511101

Emergence of rabies in the Gauteng Province, South Africa: 2010–2011

Autor: Wonderful Shumba, Jacqueline Weyer, Claude T. Sabeta, Patricia A. Leman, Debra Mohale, Jacobeth Miyen, Johan Walters, Lucille Blumberg, Janusz T. Paweska, Baby Phahladira, Peter Geertsma

Publikováno v: Journal of the South African Veterinary Association, Volume: 84, Issue: 1, Published: 2013
Journal of the South African Veterinary Association, Vol 84, Iss 1, Pp e1-e5 (2013)
Journal of the South African Veterinary Association, Vol 84, Iss 1, Pp 1-5 (2013)

Canine rabies is enzootic throughout Sub-Saharan Africa, including the Republic of South Africa. Historically, in South Africa the coastal provinces of KwaZulu-Natal and Eastern Cape were most affected. Alarmingly, outbreaks of canine rabies have bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78640fd1cc5629f69f709f2526d4d688
https://doi.org/10.4102/jsava.v84i1.923

Evaluation of a rapid immunodiagnostic test kit for detection of African lyssaviruses from brain material

Autor: K. le Roux, Wonderful Shumba, Louis Hendrik Nel, G.C. Zulu, D. York, Wanda Markotter, Claude T. Sabeta

Publikováno v: Scopus-Elsevier
Onderstepoort Journal of Veterinary Research, Vol 76, Iss 2, Pp 257-262 (2009)
Onderstepoort Journal of Veterinary Research, Volume: 76, Issue: 2, Pages: 257-262, Published: 2009

Rapid immunodiagnostic test kit was evaluated against a selection of isolates of lyssavirus genotypes occurring in Africa. The test was carried out in parallel comparison with the fluorescent antibody test (FAT) and isolates representing previously e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eec7deab26267236d27041d2d638f7f
http://www.scopus.com/inward/record.url?eid=2-s2.0-77954802470&partnerID=MN8TOARS