Zobrazeno 1 - 10 of 220 pro vyhledávání: '"Won-kyung Kim"'
1
Akademický článek
Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
Autor: Youngbum Yoo, MyeongHoon Yeon, Won-Kyung Kim, Hyeon-Bin Shin, Seung-Min Lee, Mee-Sup Yoon, Hyunju Ro, Young-Kyo Seo
Publikováno v: Experimental and Molecular Medicine, Vol 56, Iss 4, Pp 922-934 (2024)
Abstract Skeletal muscle aging results in the gradual suppression of myogenesis, leading to muscle mass loss. However, the specific role of cardiolipin in myogenesis has not been determined. This study investigated the crucial role of mitochondrial c
Externí odkaz: https://doaj.org/article/e79218984b8b4a2d938736bba649a8d3
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2
Akademický článek
Effects of intermediate annealing time on texture evolution during multi-pass cold-shear-straining of an Al–Mg–Si–Cu alloy
Autor: Hyeon-Woo Son, Chan-Ho Jeon, Taeo Son, Yun-Soo Lee, Won-Kyung Kim, Soong-Keun Hyun
Publikováno v: Journal of Materials Research and Technology, Vol 24, Iss , Pp 6000-6008 (2023)
This study examines the effects of different intermediate annealing times during multi-pass cold-torsion tests on the microstructure in alloys of aluminum, magnesium, silicon, and copper (Al–Mg–Si–Cu). The mean flow stress, when the intermediat
Externí odkaz: https://doaj.org/article/8e03b370184846ad9ea7f84453ea4f20
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5
Akademický článek
Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer
Autor: Woong Sub Byun, Won Kyung Kim, Hae Ju Han, Hwa-Jin Chung, Kyungkuk Jang, Han Sun Kim, Sunghwa Kim, Donghwa Kim, Eun Seo Bae, Sunghyouk Park, Jeeyeon Lee, Hyeung-geun Park, Sang Kook Lee
Publikováno v: Molecular Therapy: Oncolytics, Vol 15, Iss , Pp 140-152 (2019)
Triple-negative breast cancer (TNBC) is the most intractable cancer in women with a high risk of metastasis. While hyper-methylation of histone H3 catalyzed by disruptor of telomeric silencing 1-like (DOT1L), a specific methyltransferase for histone
Externí odkaz: https://doaj.org/article/710da8fe56c04d2f8fa3bd09c61234b3
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6
Akademický článek
Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells
Autor: Duc-Hiep Bach, Donghwa Kim, Song Yi Bae, Won Kyung Kim, Ji-Young Hong, Hye-Jung Lee, Nirmal Rajasekaran, Soonbum Kwon, Yanhua Fan, Thi-Thu-Trang Luu, Young Kee Shin, Jeeyeon Lee, Sang Kook Lee
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 455-467 (2018)
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are used clinically as target therapies for lung cancer patients, but the occurrence of acquired drug resistance limits their efficacy. Nicotinamide N-methyltransferase (NNMT), a
Externí odkaz: https://doaj.org/article/2804ca286597425e906de0ef1a595b55
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