Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Won-Jung Bae"'
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146708 (2016)
Recent reports suggest that thymosin beta-4 (Tβ4) is a key regulator for wound healing and anti-inflammation. However, the role of Tβ4 in osteoclast differentiation remains unclear.The purpose of this study was to evaluate Tβ4 expression in H2O2-s
Externí odkaz:
https://doaj.org/article/3d5253f637d54363871172b269fdcc44
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1742 (2018)
The present study evaluated the protective effects of melatonin in ethanol (EtOH)-induced senescence and osteoclastic differentiation in human periodontal ligament cells (HPDLCs) and cementoblasts and the underlying mechanism. EtOH increased senescen
Externí odkaz:
https://doaj.org/article/8a61bc556b904afb8ce31705f1a7d49e
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Abstract Background Protein tyrosine phosphatase receptor delta (PTPRD) is frequently inactivated in various types of cancers. Here, we explored the underlying mechanism of PTPRD-loss-induced cancer metastasis and investigated an efficient treatment
Externí odkaz:
https://doaj.org/article/c66418fe1be94560b30dfdc527492d81
Autor:
Ji-Hye Choi, Young-Bae Kim, Ji Mi Ahn, Min Jae Kim, Won Jung Bae, Sang-Uk Han, Hyun Goo Woo, Dakeun Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-11 (2018)
Gastric cancer: Mutations in cells that spread A study of genetic changes accompanying the spread of gastric cancer to lymph nodes could assist diagnosis and therapy. The spread of diffuse-type gastric cancer (DGC) into lymph nodes significantly comp
Externí odkaz:
https://doaj.org/article/42bba62ea04c433db5338e361d56f890
Publikováno v:
Biochemical and Biophysical Research Communications. 613:180-186
miRNA (miR)-4742-5p is a recently identified microRNA regarding progression and metastasis in gastric cancer (GC). However, the biological function of this novel miRNA is largely unknown. We identified that the miR-4742-5p expression level was variab
Autor:
Dakeun Lee, Jin-Hyung Heo, Chang Ohk Sung, Ji Mi Ahn, Seokhwi Kim, Won Jung Bae, Kyoung-Mee Kim, Kyeong Woon Choi
Publikováno v:
Modern Pathology. 34:672-683
Although a certain proportion of intramucosal carcinomas (IMCs) of the stomach does metastasize, the majority of patients are currently treated with endoscopic resection without lymph node dissection, and this potentially veils any existing metastasi
Autor:
Yoon-Ha Go, Woo Hee Choi, Won Jung Bae, Sook-In Jung, Chang-Hoon Cho, Seung Ah Lee, Joon Seong Park, Ji Mi Ahn, Sung Won Kim, Kyung Jin Lee, Dakeun Lee, Jongman Yoo
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2077
Pancreatic cancer is a devastating disease and is highly resistant to anticancer drugs because of its complex microenvironment. Cancer-associated fibroblasts (CAFs) are an important source of extracellular matrix (ECM) components, which alter the phy
Publikováno v:
International Journal of Cancer. 145:916-926
Notwithstanding remarkable treatment success with anti-PD-1 monoclonal antibody, oncogenic mechanism of PD-L1 regulation in gastric cancer (GC) remains poorly understood. We hypothesized that ARID1A might be related to tumor PD-L1 expression in GC. W
Publikováno v:
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 24(3)
Despite the promising preclinical antitumor activity of MET-targeting therapies, most clinical trials have failed. We introduced a new concept of quantitation of stroma-induced hepatocyte growth factor (HGF) to assess the actual MET signalling activi
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Background Protein tyrosine phosphatase receptor delta (PTPRD) is frequently inactivated in various types of cancers. Here, we explored the underlying mechanism of PTPRD-loss-induced cancer metastasis and investigated an efficient treatment option fo