Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Won-Jun Noh"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This study aimed to develop and evaluate a deep learning-based system for the automatic measurement of angles (specifically, Meary’s angle and calcaneal pitch) in weight-bearing lateral radiographs of the foot for flatfoot diagnosis. We ut
Externí odkaz:
https://doaj.org/article/109fad22a6d24843ae0db687c1c8768c
Autor:
Songming Peng, Jesse M. Zaretsky, Alphonsus H.C. Ng, William Chour, Michael T. Bethune, Jongchan Choi, Alice Hsu, Elizabeth Holman, Xiaozhe Ding, Katherine Guo, Jungwoo Kim, Alexander M. Xu, John E. Heath, Won Jun Noh, Jing Zhou, Yapeng Su, Yue Lu, Jami McLaughlin, Donghui Cheng, Owen N. Witte, David Baltimore, Antoni Ribas, James R. Heath
Publikováno v:
Cell Reports, Vol 28, Iss 10, Pp 2728-2738.e7 (2019)
Summary: Neoantigen-specific T cells are increasingly viewed as important immunotherapy effectors, but physically isolating these rare cell populations is challenging. Here, we describe a sensitive method for the enumeration and isolation of neoantig
Externí odkaz:
https://doaj.org/article/43a6df712a824f30a578af81377be174
Autor:
John E. Heath, Alphonsus H. C. Ng, Songming Peng, Won Jun Noh, Jami McLaughlin, William Chour, Xiaozhe Ding, Michael T. Bethune, Antoni Ribas, Katherine Guo, Jongchan Choi, Yapeng Su, Alice Hsu, Jungwoo Kim, David Baltimore, Donghui Cheng, Elizabeth Holman, Jesse M. Zaretsky, Jing Zhou, James R. Heath, Yue Lu, Alexander M. Xu, Owen N. Witte
Publikováno v:
Cell reports
Cell reports, vol 28, iss 10
Cell Reports, Vol 28, Iss 10, Pp 2728-2738.e7 (2019)
Cell reports, vol 28, iss 10
Cell Reports, Vol 28, Iss 10, Pp 2728-2738.e7 (2019)
SUMMARY Neoantigen-specific T cells are increasingly viewed as important immunotherapy effectors, but physically isolating these rare cell populations is challenging. Here, we describe a sensitive method for the enumeration and isolation of neoantige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c69d974ca195fd2061e9b5140e04cab
https://resolver.caltech.edu/CaltechAUTHORS:20190903-130240129
https://resolver.caltech.edu/CaltechAUTHORS:20190903-130240129
Autor:
Sung Yang, Michael T. Bethune, Won Jun Noh, Jongchan Choi, David Baltimore, Alexander M. Xu, Katherine Guo, Songming Peng, James R. Heath, William Chour, Alphonsus H. C. Ng
Adaptive immunity is based on peptide antigen recognition. Our ability to harness the immune system for therapeutic gain relies on the discovery of the T cell receptor (TCR) genes that selectively target antigens from infections, mutated proteins, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d540f166bce90f8461c0da8aa68d907b
Autor:
Zhe Liu, Bruce D. Walker, Jeffrey K. Weber, Huabiao Chen, Yong Ouyang, John D. Jeppson, Alok V. Joglekar, David Baltimore, Michael T. Bethune, Ruhong Zhou, Pedro A. Lamothe-Molina, Seung-gu Kang, Won Jun Noh
HIV controllers (HCs) are individuals who can naturally control HIV infection, partially due to potent HIV-specific CD8+ T cell responses. Here, we examined the hypothesis that superior function of CD8+ T cells from HCs is encoded by their T cell rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e02bf14575ee46354e66ac68c0e254
https://resolver.caltech.edu/CaltechAUTHORS:20180208-164208568
https://resolver.caltech.edu/CaltechAUTHORS:20180208-164208568
Autor:
Elizabeth Holman, Michael T. Bethune, Jesse M. Zaretsky, Antoni Ribas, Jungwoo Kim, Alexander M. Xu, John E. Heath, James R. Heath, Yapeng Su, Jing Zhou, David Baltimore, Jami McLaughlin, Xiaozhe Ding, Donghui Cheng, Owen N. Witte, Won Jun Noh, Songming Peng, Katherine Guo, Alice Hsu
Publikováno v:
SSRN Electronic Journal.
Tumor neoantigens are fragments of mutated proteins that contain the mutation, and can be presented by major histocompatibility complex molecules on tumor cells, where they are surveyed by T cells. The rapid and sensitive identification of neoantigen
Autor:
Won Jun Noh, Jang Hee Hong, Jung Bae Park, Soo Hyeon Bae, Soo Kyung Bae, Kee Dong Yoon, Han Chang Kang, Su-Min Jang
Publikováno v:
Journal of Separation Science. 36:2306-2314
A simple, robust, and rapid LC-MS/MS method has been developed and validated for the simultaneous quantitation of clopidogrel and its active metabolite (AM) in human plasma. Tris(2-carboxyethyl)phosphine (TCEP) was used as a reducing agent to detect
Publikováno v:
Toxicological Research
Carbon black, a particulate form of pure elemental carbon, is an industrial chemical with the high potential of occupational exposure. Although the relationship between exposure to particulate matters (PM) and cardiovascular diseases is well establis
Autor:
Jesse M. Zaretsky, Won Jun Noh, Alice Hsu, John E. Heath, James R. Heath, Antoni Ribas, Songming Peng, David Baltimore, Shannon R. Esswein, Michael T. Bethune
Publikováno v:
Cancer Immunology Research. 5:IA17-IA17
At the heart of most cancer immunotherapies are the specific interactions between tumor-infiltrating T cells, and the antigens that attract those T cells into the tumor. It has become increasingly apparent that (mutation containing) neoantigens likel
Autor:
James R. Heath, Jesse M. Zaretsky, Won Jun Noh, Alice Hsu, Toni Ribas, John E. Heath, Songming Peng, Shannon R. Esswein
Publikováno v:
Cancer Immunology Research. 4:IA30-IA30
At the heart of most cancer immunotherapies are the specific interactions between the principal cancer cell killers, T cells, and antigens presented by the tumor cells. Those interactions may be exposed through the use of checkpoint inhibitors, or th