Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Won-Jing, Wang"'
Autor:
Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)
Abstract Aberrant overexpression or activation of EGFR drives the development of non-small cell lung cancer (NSCLC) and acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) by secondary EGFR mutations or c-MET amplification/activation remain
Externí odkaz:
https://doaj.org/article/aaf04d699c2f45f6a88e5341ad07b036
Autor:
Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9922c5b5578240c4ba3a59bfacda25c3
Autor:
Tzu-Yuan Chiu, Chien-Hui Lo, Yi-Hsuan Lin, Yun-Di Lai, Shan-Shan Lin, Ya-Tian Fang, Wei-Syun Huang, Shen-Yan Huang, Pei-Yuan Tsai, Fu-Hua Yang, Weng Man Chong, Yi-Chieh Wu, Hsing-Chen Tsai, Ya-Wen Liu, Chia-Lin Hsu, Jung-Chi Liao, Won-Jing Wang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract The immune synapse, a highly organized structure formed at the interface between T lymphocytes and antigen-presenting cells (APCs), is essential for T cell activation and the adaptive immune response. It has been shown that this interface sh
Externí odkaz:
https://doaj.org/article/2d7d0697b64d4adca7193759cdf940be
Autor:
Yu-Hsuan Chen, Han-Hsiun Chen, Won-Jing Wang, Hsin-Yi Chen, Wei-Syun Huang, Chien-Han Kao, Sin-Rong Lee, Nai Yang Yeat, Ruei-Liang Yan, Shu-Jou Chan, Kuen-Phon Wu, Ruey-Hwa Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Activation of tumor-intrinsic innate immunity has been a major strategy for improving immunotherapy. Previously, we reported an autophagy-promoting function of the deubiquitinating enzyme TRABID. Here, we identify a critical role of TRABID i
Externí odkaz:
https://doaj.org/article/11bbe81d925149b88611bf2e8f4b6922
Autor:
Kang-Chieh Huang, Mong-Lien Wang, Shih-Jen Chen, Jean-Cheng Kuo, Won-Jing Wang, Phan Nguyen Nhi Nguyen, Karl J. Wahlin, Jyh-Feng Lu, Audrey A. Tran, Michael Shi, Yueh Chien, Aliaksandr A. Yarmishyn, Ping-Hsing Tsai, Tien-Chun Yang, Wann-Neng Jane, Chia-Ching Chang, Chi-Hsien Peng, Thorsten M. Schlaeger, Shih-Hwa Chiou
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 906-923 (2019)
Summary: X-linked juvenile retinoschisis (XLRS), linked to mutations in the RS1 gene, is a degenerative retinopathy with a retinal splitting phenotype. We generated human induced pluripotent stem cells (hiPSCs) from patients to study XLRS in a 3D ret
Externí odkaz:
https://doaj.org/article/b9f017c6d6624217abb79abd14c148e3
Autor:
Weng Man Chong, Won-Jing Wang, Chien-Hui Lo, Tzu-Yuan Chiu, Ting-Jui Chang, You-Pi Liu, Barbara Tanos, Gregory Mazo, Meng-Fu Bryan Tsou, Wann-Neng Jane, T Tony Yang, Jung-Chi Liao
Publikováno v:
eLife, Vol 9 (2020)
Subdistal appendages (sDAPs) are centriolar elements that are observed proximal to the distal appendages (DAPs) in vertebrates. Despite the obvious presence of sDAPs, structural and functional understanding of them remains elusive. Here, by combining
Externí odkaz:
https://doaj.org/article/ff4d5a7393f240cf9d3e4b30f0cda45c
Autor:
T. Tony Yang, Weng Man Chong, Won-Jing Wang, Gregory Mazo, Barbara Tanos, Zhengmin Chen, Thi Minh Nguyet Tran, Yi-De Chen, Rueyhung Roc Weng, Chia-En Huang, Wann-Neng Jane, Meng-Fu Bryan Tsou, Jung-Chi Liao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Distal appendages (DAPs) at the cilia base mediate membrane docking during ciliogenesis. Here the authors use super-resolution microscopy to map 16 centriole distal end components, revealing the structure of the backbone of the DAP, as well as a prev
Externí odkaz:
https://doaj.org/article/fc52cee4ed1b40db955022dc053ae118
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Mutations in many centriolar protein-encoding genes cause primary microcephaly. Here the authors show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building
Externí odkaz:
https://doaj.org/article/17908d7c695d4446b67c1c19166df732
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 957-965 (2014)
Vertebrate centrioles lose their geometric scaffold, the cartwheel, during mitosis, concurrently with gaining the ability to recruit the pericentriolar material (PCM) and thereby function as the centrosome. Cartwheel removal has recently been implica
Externí odkaz:
https://doaj.org/article/f18303ecdb654e4092d97c15108db837
Autor:
Chien-Han Kao, Ting-Yu Su, Wei-Syun Huang, Xin-Ying Lu, Wann-Neng Jane, Chien-Yung Huang, Hung-Hsiang Huang, Won-Jing Wang
Publikováno v:
Autophagy
Centrosome amplification is a phenomenon frequently observed in human cancers, so centrosome depletion has been proposed as a therapeutic strategy. However, despite being afflicted with a lack of centrosomes, many cancer cells can still proliferate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf7b05d7ffe6732c153b8bf8a50d14a