Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Won-Ho Kang"'
Autor:
Hyo-jeong Ryu, Won-ho Kang, Taeheon Kim, Jae Kyoung Kim, Kwang-Hee Shin, Jung-woo Chae, Hwi-yeol Yun
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pharmacokinetic (PK) modeling is a useful method for investigating drug absorption, distribution, metabolism, and excretion. The most commonly used mathematical models in PK modeling are the compartment model and physiologically based pharmacokinetic
Externí odkaz:
https://doaj.org/article/eaabab5e83e243ef87d3f43888e1383f
Autor:
Lien Ngo, Jaeseong Oh, Anhye Kim, Hyun‐moon Back, Won‐ho Kang, Jung‐woo Chae, Hwi‐yeol Yun, Howard Lee
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 10, Pp 584-595 (2020)
HL2351 (hIL‐1Ra‐hyFc) is a novel recombinant protein formed by the fusion of two human interleukin‐1 receptor antagonist components into one antibody‐derived fragment crystallizable portion. Although HL2351 has a pharmacological mechanism of
Externí odkaz:
https://doaj.org/article/42fafae2b10f4a889c0303af517dd643
Autor:
Junhyung Kim, Seongsung Kwak, Mi-Sun Park, Chang-Hoon Rhee, Gi-Hyeok Yang, Jangmi Lee, Woo-Chan Son, Won-ho Kang
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/15ff99eb3ee6470eb0daaa6d44dc0900
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
In recent, Botulinum Neurotoxin A1 (BoNT/A1) has been suggested as a potential anticancer agent due to neuronal innervation in tumor cells. Although potential BoNT/A1’s mechanism of action for the tumor suppression has been gradually revealed so fa
Externí odkaz:
https://doaj.org/article/9467bb2e0cdf4fb2a5f399439996d781
Autor:
Junhyung Kim, Seongsung Kwak, Mi-Sun Park, Chang-Hoon Rhee, Gi-Hyeok Yang, Jangmi Lee, Woo-Chan Son, Won-Ho Kang
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256869 (2021)
Human serum albumin (HSA) has been widely used as a pharmaceutical excipient in Botulinum toxin serotype A (BoNT/A) products that are indicated for use in therapeutics and cosmetics. However, HSA as a human-derived material has some concerns, such as
Externí odkaz:
https://doaj.org/article/5567dfe9e40140f0bce4f59b3a844aa8
Autor:
Jaeyoon Byun, Seongsung Kwak, Jin-Hee Kwon, Minhee Shin, Dong-Kyu Lee, Chang-Hoon Rhee, Won-ho Kang, Jae-Wook Oh, Deu John M. Cruz
Publikováno v:
Toxins, Vol 14, Iss 6, p 365 (2022)
Botulinum neurotoxin type A (BoNT/A) causes muscle paralysis by blocking cholinergic signaling at neuromuscular junctions and is widely used to temporarily correct spasticity-related disorders and deformities. The paralytic effects of BoNT/A are time
Externí odkaz:
https://doaj.org/article/6849d15faa984735a87d42f7a89aba46
Autor:
Hyo-jeong Ryu, Hyun-ki Moon, Junho Lee, Gi-hyeok Yang, Sung-yoon Yang, Hwi-yeol Yun, Jung-woo Chae, Won-ho Kang
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 654 (2021)
MT921 is a new injectable drug developed by Medytox Inc. to reduce submental fat. Cholic acid is the active pharmaceutical ingredient, a primary bile acid biosynthesized from cholesterol, endogenously produced by liver in humans and other mammals. Al
Externí odkaz:
https://doaj.org/article/eadca2796e2d4fa39a4261628d167170
Autor:
Won-ho Kang, Jae-yeon Lee, Jung-woo Chae, Kyeong-Ryoon Lee, In-hwan Baek, Min-Soo Kim, Hyun-moon Back, Sangkeun Jung, Craig Shaffer, Rada Savic, Hwi-yeol Yun
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 114 (2021)
Sample sizes for single-period clinical trials, including pharmacokinetic studies, are statistically determined by within-subject variability (WSV). However, it is difficult to determine WSV without replicate-designed clinical trial data, and statist
Externí odkaz:
https://doaj.org/article/8616252597634ab59a550a02c6d48520
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 133 (2021)
Dermal fillers are gel-type substances for nonsurgical medical-device use to achieve facial rejuvenation. Currently, the most widely used skin fillers are hyaluronic-acid-based dermal fillers. This study aimed to explain the change in the volume of i
Externí odkaz:
https://doaj.org/article/75f9332577634ed0824fd3a64aa17a68
Autor:
Tae Hwan Kim, Subindra Kazi Thapa, Da Young Lee, Seung Eun Chung, Jun Young Lim, Hyeon Myeong Jeong, Chang Ho Song, Youn-Woong Choi, Sang-Min Cho, Kyu-Yeol Nam, Won-Ho Kang, Soyoung Shin, Beom Soo Shin
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 152 (2018)
This study examined the effects of esomeprazole on aceclofenac pharmacokinetics and gastrointestinal complications in rats. Aceclofenac alone, or in combination with esomeprazole, was orally administered to male Sprague-Dawley rats. Plasma concentrat
Externí odkaz:
https://doaj.org/article/66f14279bfd94c209ebb016393173434