Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Won-Ha Lee"'
Autor:
Joon Bum Kim, Ji-Eun Bae, Na Yeon Park, Doo Sin Jo, Yong Hwan Kim, Kwiwan Jeong, Pansoo Kim, Won-Ha Lee, Eunbyul Yeom, Dong-Hyung Cho
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 394-402 (2023)
ABSTRACTAutophagy plays a critical role in regulating the quality and quantity of cellular compartments; however, the mechanisms governing endoplasmic reticulum (ER) autophagy (ER-phagy) are still largely undefined. In this study, we identified sever
Externí odkaz:
https://doaj.org/article/42c53468acf141248dbdd97db3c24e33
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Background and Objective Long noncoding RNAs (lncRNAs) are crucial in regulating various physiological and pathological processes, including immune responses. LINC01686 is a lncRNA with previously uncharacterized functions in immune regulati
Externí odkaz:
https://doaj.org/article/df99eee0ca4a41da8b07828258447177
Autor:
Anup Bhusal, Jae-Hong Kim, Seung-Chan Kim, Eun Mi Hwang, Hoon Ryu, Md. Sekendar Ali, Seung-Chun Park, Won-Ha Lee, Kyoungho Suk
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113813- (2024)
Summary: Peptidoglycan recognition protein 1 (PGLYRP1) is a pattern-recognition protein that mediates antibacterial actions and innate immune responses. Its expression and role in neuroinflammatory conditions remain unclear. We observed the upregulat
Externí odkaz:
https://doaj.org/article/77f0b69a857743ef8a5ae0810ddf5ed5
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2670 (2024)
Over the past century, molecular biology’s focus has transitioned from proteins to DNA, and now to RNA. Once considered merely a genetic information carrier, RNA is now recognized as both a vital element in early cellular life and a regulator in co
Externí odkaz:
https://doaj.org/article/ea3cce401973476b97488ad50416e572
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S216- (2023)
Externí odkaz:
https://doaj.org/article/ea11ff9d4afa4e409a5bc8ac15e2e68a
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1905 (2023)
Long noncoding RNAs (lncRNAs) are molecules >200 bases in length without protein-coding functions implicated in signal transduction and gene expression regulation via interaction with proteins or RNAs, exhibiting various functions. The expression of
Externí odkaz:
https://doaj.org/article/ba6e2ec19dfb484aa30eb99f62ba9aed
Publikováno v:
Cells, Vol 11, Iss 23, p 3886 (2022)
Recent studies have suggested that mouse cathelicidin-related antimicrobial peptide (CRAMP) and its human homologue leucine leucine-37 (LL-37) play critical roles in innate immune responses. Here, we studied the role of mouse CRAMP in bacterial endot
Externí odkaz:
https://doaj.org/article/13709bd6e174478793654f1cc22d5330
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Lipocalin-2 (LCN2) is a 25 kDa secreted protein that belongs to the family of lipocalins, a group of transporters of small hydrophobic molecules such as iron, fatty acids, steroids, and lipopolysaccharide in circulation. LCN2 was previously found to
Externí odkaz:
https://doaj.org/article/cd65e1e903674d54a106c56f043aec42
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Age-related chronic inflammatory activation of microglia and their dysfunction are observed in many neurodegenerative diseases, and the potential contributions of these dysfunctional cells to neurodegeneration have been demonstrated recently. The hou
Externí odkaz:
https://doaj.org/article/9fe4b9ac6e40474bb80d1b8849b5fe87
Autor:
Gyun Jee Song, Md Habibur Rahman, Mithilesh Kumar Jha, Deepak Prasad Gupta, Sung Hee Park, Jae-Hong Kim, Sun-Hwa Lee, In-Kyu Lee, Taebo Sim, Yong Chul Bae, Won-Ha Lee, Kyoungho Suk
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
GNF-2 is an allosteric inhibitor of Bcr-Abl. It was developed as a new class of anti-cancer drug to treat resistant chronic myelogenous leukemia. Recent studies suggest that c-Abl inhibition would provide a neuroprotective effect in animal models of
Externí odkaz:
https://doaj.org/article/489d0c1ef78747cf80ead55e2cf2759a