Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Won Young Lim"'
Autor:
Angela Rivera, Won Young Lim, Eunchong Park, Patrick A. Dome, Michael J. Hoy, Ivan Spasojevic, Sheng Sun, Anna Floyd Averette, Sergio Pina-Oviedo, Praveen R. Juvvadi, William J. Steinbach, Maria Ciofani, Jiyong Hong, Joseph Heitman
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Fungal infections are of mounting global concern, and the current limited treatment arsenal poses challenges when treating such infections. In particular, infections by Cryptococcus neoformans are associated with high mortality, emphasizing
Externí odkaz:
https://doaj.org/article/ce0b324bccb346759ee1b133f5211833
Autor:
Michael J. Hoy, Eunchong Park, Hyunji Lee, Won Young Lim, D. Christopher Cole, Nicholas D. DeBouver, Benjamin G. Bobay, Phillip G. Pierce, David Fox, Maria Ciofani, Praveen R. Juvvadi, William Steinbach, Jiyong Hong, Joseph Heitman
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Calcineurin is an essential virulence factor that is conserved across human fungal pathogens, including Cryptococcus neoformans, Aspergillus fumigatus, and Candida albicans. Although an excellent target for antifungal drug development, the s
Externí odkaz:
https://doaj.org/article/117f01418524456e8457bbd3d23cdecf
Autor:
Joshua Victor, Tristan Jordan, Erica Lamkin, Kanayo Ikeh, Anthony March, Justin Frere, Andrew Crompton, Lindsay Allen, James Fanning, Won Young Lim, Daniela Muoio, Elise Fouquerel, Rachel Martindale, John Dewitt, Nicole deLance, Douglas Taatjes, Julie Dragon, Randall Holcombe, Marc Greenblatt, David Kaminsky, Jiyong Hong, Pei Zhou, Benjamin tenOever, NIMRAT CHATTERJEE
Publikováno v:
Research square.
The repertoire of coronavirus disease 2019 (COVID-19)-mediated adverse health outcomes has continued to expand in infected patients, including the susceptibility to developing long-COVID; however, the molecular underpinnings at the cellular level are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c77ead7377e9af010c1b469c3a96fc9
https://pubmed.ncbi.nlm.nih.gov/35441168
https://pubmed.ncbi.nlm.nih.gov/35441168
Autor:
Pei Zhou, David Argyle, Won Young Lim, Erica N Lamkin, Nimrat Chatterjee, Mark Gray, M. Kyle Hadden, Jiyong Hong, Kira J Fisher, Dmitry M. Korzhnev, Andrew Crompton, Jamie Deutsch, Kanayo E Ikeh
Publikováno v:
Ikeh, K E, Lamkin, E N, Crompton, A, Deutsch, J, Fisher, K J, Gray, M, Argyle, D J, Lim, W Y, Korzhnev, D M, Hadden, M K, Hong, J, Zhou, P & Chatterjee, N 2021, ' REV1 Inhibition Enhances Radioresistance and Autophagy ', Cancers, vol. 13, no. 21 . https://doi.org/10.3390/cancers13215290
Cancers
Cancers, Vol 13, Iss 5290, p 5290 (2021)
Cancers; Volume 13; Issue 21; Pages: 5290
Cancers
Cancers, Vol 13, Iss 5290, p 5290 (2021)
Cancers; Volume 13; Issue 21; Pages: 5290
Simple Summary Cancer resistance to therapy continues to be the biggest challenge in treating patients. Targeting the mutagenic translesion synthesis (TLS) polymerase REV1 was previously shown to sensitize cancer cells to chemotherapy. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d8e67b35370b9a95698d250a39a89b
https://pubmed.ncbi.nlm.nih.gov/34771454
https://pubmed.ncbi.nlm.nih.gov/34771454
Autor:
Jiyong Hong, Pei Zhou, Jinshi Zhao, Seung-Hwa Kwak, Benjamin A. Fenton, Amanda F. Ennis, Jae Cho, Won Young Lim, Colleen Cochrane, Caroline G. Webster
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a40c338855e856eed3f17502bda830f
https://doi.org/10.1096/fasebj.2021.35.s1.02956
https://doi.org/10.1096/fasebj.2021.35.s1.02956
Autor:
Won Young Lim, Pei Zhou, C. Skyler Cochrane, Caroline G. Webster, Amanda F. Ennis, Jae Cho, Seung-Hwa Kwak, Jiyong Hong, Benjamin A. Fenton
Publikováno v:
Bioorg Chem
The UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH is essential in lipid A biosynthesis and has emerged as a promising target for the development of novel antibiotics against multidrug-resistant Gram-negative pathogens. Recently, we reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172c1f451a7f36619afc042b0ff19e78
https://pubmed.ncbi.nlm.nih.gov/32663666
https://pubmed.ncbi.nlm.nih.gov/32663666
Autor:
Jiyong Hong, Seok-Yong Lee, Ellene H. Mashalidis, Aili Hao, Pyeonghwa Jeong, Do-Yeon Kwon, Seung-Hwa Kwak, Won Young Lim, Mi Jung Kim
Publikováno v:
Eur J Med Chem
Antibiotic resistance is one of the most challenging global health issues and presents an urgent need for the development of new antibiotics. In this regard, phospho-MurNAc-pentapeptide translocase (MraY), an essential enzyme in the early stages of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bb88ed9517554d732a8bbfde7f7872
https://doi.org/10.1016/j.ejmech.2021.113272
https://doi.org/10.1016/j.ejmech.2021.113272
Publikováno v:
Toxicological Research; March 2015, Vol. 31 Issue: 1 p25-32, 8p