Výsledky vyhledávání - "Won Kyung Hur"

Abstract 673: The role of mass spectrometry-based serum proteomics signatures in predicting clinical outcomes in cancer patients treated with immune check point inhibitors (ICI)

Autor: Myungwoo Nam, William Han Bae, Young Kwang Chae, Won Kyung Hur, Jin Young Hwang, Emma Yu, Chan Mi Jung, William Cheng, Eugene Kim, Leeseul Kim, Yeun Ho Lee, Yoonhee Choi

Publikováno v: Cancer Research. 81:673-673

The role of mass spectrometry-based serum proteomics signatures in predicting clinical outcomes in cancer patients treated with immune checkpoint inhibitors(ICI)Background Although immune checkpoint inhibitors (ICI) have changed the therapeutic schem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fd92c1f6b658b7b2f41d12d6a68e093
https://doi.org/10.1158/1538-7445.am2021-673

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Abstract 626: The neoantigen and immune landscape of epithelial mesenchymal transition (EMT) low and high score serous ovarian cancers

Autor: William Cheng, William Han Bae, Myungwoo Nam, Eugene Kim, Christmann Low, Yoonhee Choi, Chan Mi Jung, Jeff Chuang, Jin Young Hwang, Emma Yu, Yeun Ho Lee, Young Kwang Chae, Heayoon S. Cho, Victor Wang, Won Kyung Hur, Leeseul Kim

Publikováno v: Cancer Research. 81:626-626

Background: Apart from its role in ovarian cancer progression, epithelial-mesenchymal transition (EMT) can promote chemotherapy resistance. We aimed to analyze how the EMT score would affect the tumor microenvironment in ovarian cancer. Methods: cBio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e025e7cbdaf47291ddbd81f7af7b82c
https://doi.org/10.1158/1538-7445.am2021-626

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Abstract 451: Immune landscape of endometrial carcinoma and its association with neoantigen landscape and TGF-β signaling pathway related genes mutation status

Autor: Chan Mi Jung, Yoonhee Choi, William Cheng, Jeff Chuang, Leeseul Kim, Young Kwang Chae, William H. Bae, Eugene Kim, Won Kyung Hur, Myungwoo Nam, Heayoon S. Cho, Victor Wang, Jin Young Hwang, Yeun Ho Lee, Emma Yu

Publikováno v: Cancer Research. 81:451-451

We aimed to understand how TGF-β signaling pathway related gene mutation affects the tumor neoantigen burden and immune landscape in uterine corpus endometrial carcinoma (UCEC). cBioPortal was queried to obtain the UCEC The Cancer Genome Atlas (TCGA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12b899bcbc9ccb2cf787000417af4af3
https://doi.org/10.1158/1538-7445.am2021-451

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Abstract 453: The neoantigen and immune landscape of low and high grade serous ovarian cancers

Autor: Chan Mi Jung, Victor Wang, Yoonhee Choi, Myungwoo Nam, William Cheng, William H. Bae, Christmann Low, Won Kyung Hur, Young Kwang Chae, Jin Young Hwang, Jeff Chuang, Yeun Ho Lee, Leeseul Kim, Heayoon S. Cho, Emma Yu, Eugene Kim

Publikováno v: Cancer Research. 81:453-453

Background: Within serous ovarian cancer (SOC), high-grade serous carcinoma (HGSC) demonstrates a worse prognosis compared to low-grade serous carcinoma (LGSC). Molecular analysis of SOC has revealed a distinct pattern of mutations found between the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::851efd54638e6ba110693ec5fd1a1f3a
https://doi.org/10.1158/1538-7445.am2021-453

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Abstract 519: Hyperprogression in follicular thyroid cancer treated with combination immunotherapy

Autor: Won Kyung Hur, Chan Mi Jung, Emma Yu, Elena Vagia, Jin Young Hwang, Young Kwang Chae, Christmann Low, Heayoon S. Cho, William Cheng, Eugene Kim, Myungwoo Nam, William Han Bae, Leeseul Kim, Yoonhee Choi, Yeun Ho Lee

Publikováno v: Cancer Research. 81:519-519

Hyperprogression is a severe adverse event usually reported in immunogenic cancers such as non-small cell lung cancer (NSCLC) and melanoma after immunotherapy. Currently, there are no reported cases of hyperprogression seen in thyroid cancer. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d10265eb086173db4601c76e8af1077f
https://doi.org/10.1158/1538-7445.am2021-519

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Abstract 452: TGF-β signaling pathway-related gene mutations are associated with increased neoantigen counts, enhanced cytolytic activity, and improved survival outcomes in TP53-mutated endometrial carcinoma

Autor: William Cheng, Victor Wang, Young Kwang Chae, Jin Young Hwang, Yoonhee Choi, Yeun Ho Lee, Myungwoo Nam, William H. Bae, Jeff Chuang, Won Kyung Hur, Eugene Kim, Leeseul Kim, Chan Mi Jung, Emma Yu

Publikováno v: Cancer Research. 81:452-452

TP53-mutation is a poor prognostic marker for uterine corpus endometrial carcinoma (UCEC). TGF-β is known to promote tumor progression via immune suppression, particularly NK and T cell-mediated cytotoxicity, in the tumor microenvironment. We aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a06a8928136cd75e7953422db8d463d3
https://doi.org/10.1158/1538-7445.am2021-452

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Abstract 520: Potential role of serum proteome in predicting immune-related adverse events from immunotherapy in non-small cell lung cancer

Autor: William Han Bae, Won Kyung Hur, Chan Mi Jung, William Cheng, Jin Young Hwang, Leeseul Kim, Yeun Ho Lee, Young Kwang Chae, Yoonhee Choi, Heayoon S. Cho, Myungwoo Nam

Publikováno v: Cancer Research. 81:520-520

Early recognition of immune-related adverse events (irAEs) of immunotherapy is important. Circulating proteome reflects host response to diseases and is being explored as a marker for response to immunotherapy. We used a serum-based proteomics test,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c086e4e10b6cee38cc2feda589881aa
https://doi.org/10.1158/1538-7445.am2021-520

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