Zobrazeno 1 - 10 of 51 pro vyhledávání: '"Won Jin Chang"'
1
Akademický článek
Phase II study of nivolumab in patients with genetic alterations in DNA damage repair and response who progressed after standard treatment for metastatic solid cancers (KM-06)
Autor: Jae Ho Byun, Jeeyun Lee, Kyong Hwa Park, Eun Joo Kang, Sang Joon Shin, In Gyu Hwang, Ju Won Kim, Hyo Jin Lee, Ji Yoon Lee, Jason K Sa, Sook Ryun Park, Jung Sun Kim, Yu Jung Kim, Woo Kyun Bae, Won Jin Chang, Eun-Ok Kim
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Immune-modulating antibodies targeting programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) have demonstrated promising antitumor efficacy in various types of cancers, especially highly mutated ones. Genetic alterations i
Externí odkaz: https://doaj.org/article/3b976b2bbe094530abf0fc108109580d
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2
Akademický článek
Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA
Autor: Jong Won Lee, Young Soo Park, Jung Yoon Choi, Won Jin Chang, Soohyeon Lee, Jae Sook Sung, Boyeon Kim, Saet Byeol Lee, Sung Yong Lee, Jungmin Choi, Yeul Hong Kim
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Circulating cell-free DNA (cfDNA) can be used to characterize tumor genomes through next-generation sequencing (NGS)-based approaches. We aim to identify novel genetic alterations associated with drug resistance in lung cancer and colorectal cancer p
Externí odkaz: https://doaj.org/article/df080e4a264c4b0b9581bbe73fd0de7e
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3
Akademický článek
Efficacy and safety of cisplatin and weekly docetaxel in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
Autor: Moon Jin Kim, Sung Min Kim, Hyun Ae Jung, Jung Yong Hong, Won Jin Chang, Moon Ki Choi, Hye Sook Kim, Jong-Mu Sun, Keunchil Park, Myung-Ju Ahn
Publikováno v: The Korean Journal of Internal Medicine, Vol 34, Iss 5, Pp 1107-1115 (2019)
Background/Aims We investigated the efficacy and toxicity of a weekly schedule of docetaxel and cisplatin as a first-line treatment in patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC). Methods In this study, 18
Externí odkaz: https://doaj.org/article/22d612e4440d4beba96654dd7463f47f
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4
Akademický článek
Clinicopathological Features and Prognostic Factors Affecting Survival Outcomes in Isolated Locoregional Recurrence of Breast Cancer: Single-Institutional Series.
Autor: Min-Young Lee, Won Jin Chang, Hae Su Kim, Ji Yun Lee, Sung Hee Lim, Jeong Eon Lee, Seok Won Kim, Seok Jin Nam, Jin Seok Ahn, Young-Hyuck Im, Yeon Hee Park
Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0163254 (2016)
The purpose of this study was to investigate the clinicopathologic features and prognostic factors affecting outcome in patients with isolated locoregional recurrence of breast cancer (ILRR).We retrospectively analyzed the medical records of 104 pati
Externí odkaz: https://doaj.org/article/f5b9dbe3d0464b8d901c9cbe20d35fbf
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5
Comparison of the Data of a Next-Generation Sequencing Panel from K-MASTER Project with That of Orthogonal Methods for Detecting Targetable Genetic Alterations
Autor: Yoon Ji Choi, Jae Sook Sung, Soohyeon Lee, Seungtaek Lim, Mi Sun Ahn, Yeul Hong Kim, Jung Yoon Choi, Youngwoo Lee, Hee-Joon Chung, Hye Sook Kim, Yu Jung Kim, Jong Won Lee, Eun Joo Kang, Young Saing Kim, Won Jin Chang, Ah Reum Lim, Taekyu Lim, Ju Won Kim, Sung Shim Cho, Jang Ho Cho, Sang Won Shin, Kyong Hwa Park, Ji Hyun Park, Jung Sun Kim
Publikováno v: Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose K-MASTER project is a Korean national precision medicine platform that screened actionable mutations by analyzing next-generation sequencing (NGS) of solid tumor patients. We compared gene analyses between NGS panel from the K-MASTER project
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127907535cf8abb46fd990ff9932836f
https://doi.org/10.4143/crt.2021.218
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6
Clinical Implication of Concordant or Discordant Genomic Profiling between Primary and Matched Metastatic Tissues in Patients with Colorectal Cancer
Autor: Jung Yoon Choi, Seon Hahn Kim, Dong Sik Kim, Yoon Ji Choi, Junhee Seok, Sunho Choi, Jae Sook Sung, Yeul Hong Kim, Jin Kim, Ju Won Kim, Sung Ho Lee, Minhyeok Lee, Young Soo Park, Won Jin Chang, Kyong Hwa Park
Publikováno v: Cancer Research and Treatment : Official Journal of Korean Cancer Association
PurposeThe purpose of this study was to identify the concordant or discordant genomic profiling between primary and matched metastatic tumors in patients with colorectal cancer (CRC) and to explore the clinical implication.Materials and MethodsSurgic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bea895d674e6ef8c177624c74a769cb
http://europepmc.org/articles/PMC7373863
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7
Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA
Autor: Jong Won Lee, Young Soo Park, Jung Yoon Choi, Won Jin Chang, Soohyeon Lee, Jae Sook Sung, Boyeon Kim, Saet Byeol Lee, Sung Yong Lee, Jungmin Choi, Yeul Hong Kim
Publikováno v: Frontiers in oncology. 12
Circulating cell-free DNA (cfDNA) can be used to characterize tumor genomes through next-generation sequencing (NGS)-based approaches. We aim to identify novel genetic alterations associated with drug resistance in lung cancer and colorectal cancer p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb5b16af278ccbc883f651ab92d18e3
https://pubmed.ncbi.nlm.nih.gov/35402275
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8
Blood transfusion has an adverse impact on the prognosis of patients receiving chemotherapy for advanced colorectal cancer: experience from a single institution with a patient blood management program
Autor: Ah Reum Lim, Jwa Hoon Kim, Myung Han Hyun, Won-Jin Chang, Soohyeon Lee, Yeul Hong Kim, Kyong Hwa Park, Jong Hoon Park
Publikováno v: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 30(6)
Purpose: Perioperative blood transfusion in early stage cancer patients had a negative effect on the prognosis of patients, but the prognostic impact of transfusion in advanced cancer patients remains unclear. To minimize transfusion, a institutional
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfde716ef341a195a576a4790556ace1
https://pubmed.ncbi.nlm.nih.gov/35277757
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9
Efficacy and safety of cisplatin and weekly docetaxel in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
Autor: Hyun Ae Jung, Jung Yong Hong, Moon Ki Choi, Won Jin Chang, Sung-min Kim, Moon Jin Kim, Keunchil Park, Hye Sook Kim, Jong-Mu Sun, Myung-Ju Ahn
Publikováno v: The Korean Journal of Internal Medicine
The Korean Journal of Internal Medicine, Vol 34, Iss 5, Pp 1107-1115 (2019)
Background/Aims We investigated the efficacy and toxicity of a weekly schedule of docetaxel and cisplatin as a first-line treatment in patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC). Methods In this study, 18
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acd5f88f17df80112609f9ed111531d
https://doi.org/10.3904/kjim.2017.234
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10
The Clinical Significance of RAS, PIK3CA, and PTEN Mutations in Non-Small Cell Lung Cancer Using Cell-Free DNA
Autor: Eun Joo Kang, Jung Yoon Choi, Kyong Hwa Park, Sang Won Shin, Nak-Jung Kwon, Won Jin Chang, Yeul Hong Kim, Yoon Ji Choi, Hae Mi Kim, Jae Sook Sung, Sung Yong Lee, Ju Won Kim
Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 2642, p 2642 (2020)
Journal of Clinical Medicine
Volume 9
Issue 8
Mutations in the EGFR gene downstream signaling pathways may cause receptor-independent pathway activation, making tumors unresponsive to EGFR inhibitors. However, the clinical significance of RAS, PIK3CA or PTEN mutations in NSCLC is unclear. In thi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a8c8225c747ebfe8e53f4c4dea9ed4
https://www.mdpi.com/2077-0383/9/8/2642
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