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In vitro generation of tau aggregates conformationally distinct from parent tau seeds of Alzheimer’s brain

Autor: Won-Hee Nam, Young Pyo Choi

Publikováno v: Prion. 13:1-12

Normal monomeric tau can be converted into pathogenic aggregates and acquire protease resistance in a prion-like manner. This acquisition of partial protease-resistance in tau aggregates has to dat...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afd0407abcf7b1c243fdf24038160c9a
https://doi.org/10.1080/19336896.2018.1545524

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15-Hydroxyprostaglandin Dehydrogenase is Downregulated and Exhibits Tumor Suppressor Activity in Gastric Cancer

Autor: Hwoon-Yong Jung, Jin-Yong Jeong, Jin-Ho Kim, Yeon Mi Ryu, In Wha Kim, Won Hee Nam, Stephen P. Fink, Young Soo Park, Ho June Song, Seung-Jae Myung, Sun-Mi Lee, Dong-Hoon Yang

Publikováno v: Cancer Investigation. 29:257-265

We investigated the tumor suppressor activity and regulatory mechanism of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in gastric cancer; 15-PGDH expression was lost in 70.1% of malignant human gastric tissues, but was preserved in normal and meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f64106a6132cd8a40ac2e5934d9a331
https://doi.org/10.3109/07357907.2011.568562

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Adiponectin and adiponectin receptor in relation to colorectal cancer progression

Autor: Sun-Mi Lee, Seung-Jae Myung, Jin-Yong Jeong, Jin-Ho Kim, Jae Gyu Kim, Won-Hee Nam, Dong Jin Suh, Mi-Jung Kim, Suk-Kyun Yang, Jeong-Sik Byeon

Publikováno v: International Journal of Cancer. 127:2758-2767

Although obesity is a risk factor for colorectal cancer, the underlying mechanism is not clear. Adiponectin is an adipokine that binds to 2 types of receptors, AdipoR1 and AdipoR2. The plasma concentrations of adiponectin are reduced in obese individ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69e026470cbd14118a6b3de06991788
https://doi.org/10.1002/ijc.25301

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Mechanism of Metronidazole Resistance Regulated by the fdxA Gene in Helicobacter pylori

Autor: Jin-Ho Kim, Won-Hee Nam, Eun-Sil Kim, Jin-Yong Jeong, Sun-Mi Lee

Publikováno v: Journal of Life Science. 17:723-727

Resistance to metronidazole in Helicobacter pylori results from inactivation of rdxA and frxA, the chromosomal genes for a nitroreductase that normally converts metronidazole from prodrug to bactericidal agent. Two types of metronidazole susceptible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7fd53f8dd2ae9c5442f602ce387cc5b
https://doi.org/10.5352/jls.2007.17.5.723

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Atomic Layer Chemical Vapor Deposition (ALCVD) of Hf and Zr Silicate and Aluminate High-k Gate Dielectric for Next Generation Nano Devices

Autor: Won-Hee Nam, Shi-Woo Rhee, Suk-Hoon Kim, Won-Kyu Kim

Publikováno v: JOURNAL OF CHEMICAL ENGINEERING OF JAPAN. 38:578-587

Among many deposition techniques, atomic layer deposition (ALD) is well suited for highly conformal and uniform ultrathin films with accurate thickness control over a large area. A number of ALD deposition processes have been used to grow mixed oxide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::181911408adcf7a76302e0dc2d03bbf5
https://doi.org/10.1252/jcej.38.578

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Atomic Layer Deposition of ZrO2 Thin Films Using Dichlorobis[bis-(trimethylsilyl)amido]zirconium and Water

Autor: Won-Hee Nam, Shi-Woo Rhee

Publikováno v: Chemical Vapor Deposition. 10:201-205

A new zirconium precursor, (ZrCl 2 [N(SiMe 3 ) 2 ] 2 ), and H 2 O oxidant were used to deposit ZrO 2 films on a Si substrate, for alternative gate dielectrics, via atomic layer deposition (ALD) in the temperature range 150-350°C. The film growth sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9eff92c3ade9e0a88dbc74ef8aed2a
https://doi.org/10.1002/cvde.200306277

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The Helicobacter pylori Mfd protein is important for antibiotic resistance and DNA repair

Autor: Hwoon-Yong Jung, Kee Don Choi, Jhang-Ho Pak, Jin-Ho Kim, Jun-Won Chung, Ho June Song, Jin-Yong Jeong, Won-Hee Nam, Gin Hyug Lee, Sun-Mi Lee

Publikováno v: Diagnostic microbiology and infectious disease. 65(4)

A Helicobacter pylori mutant defective in a putative mfd gene was constructed and characterized. The mfd gene is required for DNA repair and is involved in DNA recombination processes. The mfd mutant strain displayed a greatly increased susceptibilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777fc5c82e60b62806a6858723ecf8f3
https://pubmed.ncbi.nlm.nih.gov/19766427

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