Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Won‑Ki Huh"'
Autor:
Chulwon Choi, Jungnam Bae, Seonghan Kim, Seho Lee, Hyunook Kang, Jinuk Kim, Injin Bang, Kiheon Kim, Won-Ki Huh, Chaok Seok, Hahnbeom Park, Wonpil Im, Hee-Jung Choi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Structural and mechanistic studies on human odorant receptors (ORs), key in olfactory signaling, are challenging because of their low surface expression in heterologous cells. The recent structure of OR51E2 bound to propionate provided molec
Externí odkaz:
https://doaj.org/article/83319c59223f42e0b713a56c562fbed1
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background G protein-coupled receptor heteromerization is believed to exert dynamic regulatory impact on signal transduction. CXC chemokine receptor 4 (CXCR4) and its ligand CXCL12, both of which are overexpressed in many cancers, play a piv
Externí odkaz:
https://doaj.org/article/9cb5242ea2ba4cfab8358d045e5574f0
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f7ccdda4438a4524b976efcfe42676c6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract C-X-C chemokine receptor 4 (CXCR4) is widely overexpressed in various types of cancer and is involved in several cancer phenotypes including tumor growth, survival, and metastasis. The roles of histamine and histamine receptor H1 (HRH1) in c
Externí odkaz:
https://doaj.org/article/a2cb3366055042378e7f4d829fbabe37
Autor:
Devki D Sukhtankar, Juan José Fung, Mi-Na Kim, Thomas Cayton, Valerie Chiou, Niña G Caculitan, Piotr Zalicki, Sujeong Kim, Yoonjung Jo, SoHui Kim, Jae Min Lee, Junhee Choi, SeongGyeong Mun, Ashley Chin, Yongdae Jang, Ji Yeong Lee, Gowoon Kim, Eun Hee Kim, Won-Ki Huh, Jae-Yeon Jeong, Dong-Seung Seen, Pina M Cardarelli
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0287863 (2023)
Autologous Stem Cell Transplant (ASCT) is increasingly used to treat hematological malignancies. A key requisite for ASCT is mobilization of hematopoietic stem cells into peripheral blood, where they are collected by apheresis and stored for later tr
Externí odkaz:
https://doaj.org/article/1ffb04feab5e4aee94fe16c155bd7935
Autor:
Komudi Singh, Mid Eum Lee, Maryam Entezari, Chan-Hun Jung, Yeonsoo Kim, Youngmin Park, Jack D. Fioretti, Won-Ki Huh, Hay-Oak Park, Pil Jung Kang
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 3, Pp 921-931 (2019)
Rho GTPases play critical roles in cell proliferation and cell death in many species. As in animal cells, cells of the budding yeast Saccharomyces cerevisiae undergo regulated cell death under various physiological conditions and upon exposure to ext
Externí odkaz:
https://doaj.org/article/0ae7a393f1e84aea99340638bbd6ede2
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198619 (2018)
Mitochondrial dysfunction leads to the accumulation of reactive oxygen species (ROS) which is associated with cellular dysfunction, disease etiology, and senescence. Here, we used the eukaryotic model Saccharomyces cerevisiae, commonly studied for ce
Externí odkaz:
https://doaj.org/article/bee451e87259409c8f2ba63f1bbc2b8e
Autor:
Junyi Liang, Seghiri, Mohamed, Singh, Pradeep Kumar, Hyeon Gyu Seo, Ji Yeong Lee, Yoonjung Jo, Yong Bhum Song, Chulo Park, Zalicki, Piotr, Jae-Yeon Jeong, Won-Ki Huh, Caculitan, Niña G., Smith, Adam W.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/2/2024, Vol. 121 Issue 14, p1-8, 23p
Macroautophagy/autophagy is a key catabolic pathway in which double-membrane autophagosomes sequester various substrates destined for degradation, enabling cells to maintain homeostasis and survive under stressful conditions. Several autophagy-relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d4cfaabbbf974fc050ece25d4db641
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1864(12)
In the endoplasmic reticulum (ER) membrane, transmembrane (TM) domain insertion occurs through the Sec61 channel with its auxiliary components, including Sec62. Sec62 interacts with the Sec61 channel and is located on the front side of the Sec61 late
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f56a2b75795fd8a818299c436bd9276
https://pubmed.ncbi.nlm.nih.gov/36122759
https://pubmed.ncbi.nlm.nih.gov/36122759