Two alleles of Med31 provide a model to study delayed fetal growth, proliferation and placental development

Autor: Wolton, Kathryn

Fetal growth restriction (FGR) is the failure of a fetus to reach its pre-determined genetic growth potential during development. FGR is associated both with poor outcome in the neonatal period, and the onset of major adult diseases such as diabetes,

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694292

A mathematical model of the role of aggregation in sonic hedgehog signalling.

Autor: Derrick, Daniel J. A.¹ (AUTHOR), Wolton, Kathryn² (AUTHOR), Currie, Richard A.² (AUTHOR), Tindall, Marcus John^1,3 (AUTHOR) m.tindall@reading.ac.uk

Publikováno v: PLoS Computational Biology. 2/22/2021, Vol. 17 Issue 2, p1-20. 20p. 1 Color Photograph, 1 Chart, 8 Graphs.

Zfp521 promotes B-cell viability and cyclin D1 gene expression in a B cell culture system

Autor: Wolton, Kathryn, Hentges, Kathryn

Publikováno v: Wolton, K & Hentges, K 2016, ' Zfp521 promotes B-cell viability and cyclin D1 gene expression in a B cell culture system. ', Leukemia Research, vol. 46, pp. 10-17 . https://doi.org/10.1016/j.leukres.2016.03.013

Leukemia arises due to the dysregulated proliferation of hematopoietic progenitor cells. Errors in the multi-step commitment process result in excessive numbers of immature lymphocytes, causing malignant disease. Genes involved in the differentiation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::37b2b68a3ed89930e870174b7cdaa346
https://www.research.manchester.ac.uk/portal/en/publications/zfp521-promotes-bcell-viability-and-cyclin-d1-gene-expression-in-a-b-cell-culture-system(879e6424-6be8-4490-9ecb-b74dcf1231ea).html

Applying discovery toxicology approaches for prediction of developmental phenotypes – a case study

Autor: Wolton, Kathryn, Barnes, Emma, Currie, Richard

Publikováno v: In Reproductive Toxicology September 2018 80:14-14