Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Wollnitzke P"'
Autor:
Yadi Tang, Mariola Majewska, Britta Leß, Ilir Mehmeti, Philipp Wollnitzke, Nina Semleit, Bodo Levkau, Julie D. Saba, Gerhild van Echten-Deckert, Ewa Gurgul-Convey
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 8, Pp 100587- (2024)
Lipotoxicity has been considered the main cause of pancreatic beta-cell failure during type 2 diabetes development. Lipid droplets (LD) are believed to regulate the beta-cell sensitivity to free fatty acids (FFA), but the underlying molecular mechani
Externí odkaz:
https://doaj.org/article/f3e16ef9cddd4886b684f4887a91e450
Autor:
Nadine Thomas, Nathalie H. Schröder, Melissa K. Nowak, Philipp Wollnitzke, Shahrooz Ghaderi, Karin von Wnuck Lipinski, Annalena Wille, Jennifer Deister-Jonas, Jens Vogt, Markus H. Gräler, Lisa Dannenberg, Tobias Buschmann, Philipp Westhoff, Amin Polzin, Malte Kelm, Petra Keul, Sarah Weske, Bodo Levkau
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Red blood cells (RBC) are the major carriers of sphingosine-1-phosphate (S1P) in blood. Here we show that variations in RBC S1P content achieved by altering S1P synthesis and transport by genetic and pharmacological means regulate glucose up
Externí odkaz:
https://doaj.org/article/e7bc77bce542466b84c00d135951cee7
Akademický článek
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Autor:
Amin Polzin, Lisa Dannenberg, Marcel Benkhoff, Maike Barcik, Carolin Helten, Philipp Mourikis, Samantha Ahlbrecht, Laura Wildeis, Justus Ziese, Dorothee Zikeli, Daniel Metzen, Hao Hu, Leonard Baensch, Nathalie H. Schröder, Petra Keul, Sarah Weske, Philipp Wollnitzke, Dragos Duse, Süreyya Saffak, Mareike Cramer, Florian Bönner, Tina Müller, Markus H. Gräler, Tobias Zeus, Malte Kelm, Bodo Levkau
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Antiplatelet medication is standard of care in acute myocardial infarction (AMI). However, it may have obscured beneficial properties of the activated platelet secretome. We identify platelets as major source of a sphingosine-1-phosphate (S1
Externí odkaz:
https://doaj.org/article/69086935381d4c428839f590beca54d4
Autor:
Fabian Stuhldreier, Laura Schmitt, Thomas Lenz, Ilka Hinxlage, Marcel Zimmermann, Philipp Wollnitzke, Julian Schliehe-Diecks, Yang Liu, Paul Jäger, Stefanie Geyh, Nicole Teusch, Christoph Peter, Sanil Bhatia, Rainer Haas, Bodo Levkau, Andreas S. Reichert, Kai Stühler, Peter Proksch, Björn Stork, Sebastian Wesselborg
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-17 (2022)
Abstract Inhibition of the mitochondrial metabolism offers a promising therapeutic approach for the treatment of cancer. Here, we identify the mycotoxin viriditoxin (VDT), derived from the endophytic fungus Cladosporium cladosporioides, as an interes
Externí odkaz:
https://doaj.org/article/7e96c5faca6e4597a6d4c5bd9fe0a680
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Akademický článek
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Autor:
Benkhoff M; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany.; Institute of Analytical Chemistry, University of Vienna, Austria (M. Benkhoff, C.C., R.A., B.L.).; Department of Cardiac Surgery, University Hospital Aachen, RWTH Aachen University, Germany (M.B., P.A.)., Barcik M; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Mourikis P; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Dahlmanns J; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Kahmann P; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Wollnitzke P; Medical Faculty, Institute of Molecular Medicine III (P.W., J. Hoppe, N.S., J.D.-J.), Heinrich Heine University Düsseldorf, Germany., Hering M; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Huckenbeck T; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Hoppe J; Medical Faculty, Institute of Molecular Medicine III (P.W., J. Hoppe, N.S., J.D.-J.), Heinrich Heine University Düsseldorf, Germany., Semleit N; Medical Faculty, Institute of Molecular Medicine III (P.W., J. Hoppe, N.S., J.D.-J.), Heinrich Heine University Düsseldorf, Germany., Deister-Jonas J; Medical Faculty, Institute of Molecular Medicine III (P.W., J. Hoppe, N.S., J.D.-J.), Heinrich Heine University Düsseldorf, Germany., Zako S; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Seel J; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Coman C; Institute of Analytical Chemistry, University of Vienna, Austria (M. Benkhoff, C.C., R.A., B.L.)., Barth M, Cramer M; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Helten C; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Wildeis L; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Hu H; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Al-Kassis G; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Metzen D; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Hesse J; University Hospital Düsseldorf, Department of Molecular Cardiology (J. Hesse), Heinrich Heine University Düsseldorf, Germany., Weber J; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Dannenberg L; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Akhyari P; Department of Cardiac Surgery, University Hospital Aachen, RWTH Aachen University, Germany (M.B., P.A.)., Lichtenberg A; Department of Cardiac Surgery (A.L.), Heinrich Heine University Düsseldorf, Germany., Quast C; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Gerdes N; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany.; Cardiovascular Research Institute Düsseldorf, Germany (N.G., M.K., A.P.)., Zeus T; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany., Borst O; Deutsche Forschungsgemeinschaft Heisenberg Group Cardiovascular Thromboinflammation and Translational Thrombocardiology (O.B.), University of Tübingen, Germany.; Department of Cardiology and Angiology (O.B.), University of Tübingen, Germany., Kelm M; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany.; Cardiovascular Research Institute Düsseldorf, Germany (N.G., M.K., A.P.)., Petzold T; Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Germany (T.P.).; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Germany (T.P.)., Ahrends R; Institute of Analytical Chemistry, University of Vienna, Austria (M. Benkhoff, C.C., R.A., B.L.)., Levkau B; Institute of Analytical Chemistry, University of Vienna, Austria (M. Benkhoff, C.C., R.A., B.L.)., Polzin A; Department of Cardiology, Pulmonology, and Vascular Medicine (M. Benkhoff, M. Barcik, P.M., J.D., P.K., M.H., T.H., S.Z., J.S., M.C., C.H., L.W., H.H., G.A.-K., D.M., J.W., L.D., C.Q., N.G., T.Z., M.K., A.P.), Heinrich Heine University Düsseldorf, Germany.; Cardiovascular Research Institute Düsseldorf, Germany (N.G., M.K., A.P.).; National Heart and Lung Institute, Imperial College London, United Kingdom (A.P.).
Publikováno v:
Circulation [Circulation] 2024 Oct 21. Date of Electronic Publication: 2024 Oct 21.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.