Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Wolfram Eichler"'
Autor:
Wolfram Eichler, Helena Savković-Cvijić, Susanne Bürger, Mike Beck, Manuela Schmidt, Peter Wiedemann, Andreas Reichenbach, Jan Darius Unterlauft
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1411-1424 (2017)
Background/ Aims: This study was performed to reveal signaling pathways exploited by pigment epithelium-derived factor (PEDF) derived from retinal (glial) Müller cells to protect retinal ganglion cells (RGCs) from cell death. Methods: The survival o
Externí odkaz:
https://doaj.org/article/55db7f32031d4927bf0e59fb4b2c0739
Autor:
Susanne Bürger, Jie Meng, Annette Zwanzig, Mike Beck, Maik Pankonin, Peter Wiedemann, Wolfram Eichler, Jan Darius Unterlauft
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 369 (2020)
The demise of retinal ganglion cells (RGCs) is characteristic of diseases of the retina such as glaucoma and diabetic or ischemic retinopathies. Pigment epithelium-derived factor (PEDF) is a multifunctional secreted protein that mediates neuroprotect
Externí odkaz:
https://doaj.org/article/822d24d975b8409ab0c616cde790ec22
Autor:
Yousef Yafai, Ianors Iandiev, Johannes Lange, Xiu Mei Yang, Peter Wiedemann, Andreas Bringmann, Wolfram Eichler
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68773 (2013)
Basic fibroblast growth factor (bFGF) is a pleiotropic cytokine with pro-angiogenic and neurotrophic effects. The angioregulatory role of this molecule may become especially significant in retinal neovascularization, which is a hallmark of a number o
Externí odkaz:
https://doaj.org/article/6a9a9024a9fe45f3b74e226b086f95cd
Akademický článek
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Autor:
Annette Zwanzig, Jan Darius Unterlauft, Peter Wiedemann, Manuela Schmidt, Wolfram Eichler, Jie Meng, Maik Pankonin, Susanne Bürger, Heidi Müller
Publikováno v:
Experimental Eye Research. 209:108689
Progressive retinal ganglion cell (RGC) loss underlies a number of retinal neurodegenerative disorders, which may lead to permanent vision loss. However, secreted neuroprotective factors, such as PEDF, VEGF and IL-6, which are produced by Muller cell
Publikováno v:
Klinische Monatsblätter für Augenheilkunde. 235:58-63
Zusammenfassung Einleitung Die Müllerʼschen Gliazellen übernehmen in der Netzhaut vielfältige Aufgaben und gewährleisten damit deren regelrechte Funktion. Wie stark die neuroprotektive Wirkung von Müller-Zellen auf retinale Ganglienzellen (RGC)
Autor:
Helena Savkovic-Cvijic, Peter Wiedemann, Michael Beck, Jan Darius Unterlauft, Susanne Bürger, Wolfram Eichler, Andreas Reichenbach, Manuela Schmidt
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1411-1424 (2017)
Background/ Aims: This study was performed to reveal signaling pathways exploited by pigment epithelium-derived factor (PEDF) derived from retinal (glial) Müller cells to protect retinal ganglion cells (RGCs) from cell death. Methods: The survival o
Autor:
Wolfram Eichler, Johannes Kacza, Andreas Bringmann, Soichiro Kuwayama, Yousef Yafai, Aki Kato, Hideaki Usui, Akiko Nishiwaki, Ayae Kubota, Yuichiro Ogura, Kazuki Ohashi, Peter Wiedemann, Noriaki Takase, Rina Wako, Tsutomu Yasukawa, Johannes Seeger, Lanors Landiev
Publikováno v:
Journal of Cell Science.
Age-related macular degeneration (AMD) is a leading cause of legal blindness in people over 50 years of age in many developed countries. Drusen are yellowish extracellular deposits beneath retinal pigment epithelium (RPE) found in aging eyes and cons
Autor:
Peter Ruschpler, Ellen Svanidze, Frank Emmrich, Wolfram Eichler, Stephan Fricke, Christoper Oelkrug, Andreas Boldt, Nadja Hilger, Felix Schmidt
Publikováno v:
Cytometry Part A. 87:334-345
Acute Graft-versus-Host-Disease (aGvHD) is one of the major complications following allogeneic hematopoietic stem cell transplantation (HSCT). Although rather helpful, the use of conventional immunosuppressive drugs leads to general immunosuppression
Publikováno v:
Klinische Monatsblatter fur Augenheilkunde. 235(1)
Müller glial cells carry out different tasks to warrant normal retinal functions. The aim of this study was to investigate if Müller cells also support retinal ganglion cells (RGC).RGC were cultured for 24 hours in the presence or absence of Mülle