Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Wolfram, Jochum"'
Autor:
Nathalie A. Lengacher, Julianna J. Tomlinson, Ann‑Kristin Jochum, Jonas Franz, Omar Hasan Ali, Lukas Flatz, Wolfram Jochum, Josef Penninger, aSCENT-PD Investigators, Christine Stadelmann, John M. Woulfe, Michael G. Schlossmacher
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/c118a156131a4fa38a92b2f413f8b91a
Autor:
Jeanine Wakim El-Khoury, Ekaterina Safroneeva, Catherine Saner, Jean-Benoit Rossel, Sven Trelle, Marcel Zwahlen, Luc Biedermann, Andrea Kreienbuehl, Thomas Greuter, Philipp Schreiner, Peter Netzer, Annett Franke, Stephan Brand, Chantal Hasler, Patrick Aepli, Emanuel Burri, Achim Weber, Christine Sempoux, Ruggero Biral, Wolfram Jochum, Joachim Diebold, Niels Willi, Alex Straumann, Alain M. Schoepfer
Publikováno v:
Inflammatory Intestinal Diseases, Vol 9, Iss 1, Pp 165-173 (2024)
Introduction: The Swiss Eosinophilic Esophagitis Cohort Study (SEECS) is a national cohort that was established in 2015 with the aim of improving quality of care of affected adults with eosinophilic esophagitis (EoE). Between 2020 and 2022, paper que
Externí odkaz:
https://doaj.org/article/9cc813641253435cb4165babb8fda911
Autor:
Dilara Akhoundova, Stefanie Fischer, Joanna Triscott, Marika Lehner, Phillip Thienger, Sina Maletti, Muriel Jacquet, Dinda S.H. Lubis, Lukas Bubendorf, Wolfram Jochum, Mark A. Rubin
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Catenin (Cadherin-Associated Protein), Beta 1 (CTNNB1) genomic alterations are rare in prostate cancer (PCa). Gain-of-function mutations lead to overexpression of β-catenin, with consequent hyperactivation of the Wnt/β-catenin s
Externí odkaz:
https://doaj.org/article/ab8d7da124964dd89f2c5fdc280d36be
Autor:
Nathalie A. Lengacher, Julianna J. Tomlinson, Ann-Kristin Jochum, Jonas Franz, Omar Hasan Ali, Lukas Flatz, Wolfram Jochum, Josef Penninger, aSCENT-PD Investigators, Christine Stadelmann, John M. Woulfe, Michael G. Schlossmacher
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract The majority of patients with Parkinson disease (PD) experience a loss in their sense of smell and accumulate insoluble α-synuclein aggregates in their olfactory bulbs (OB). Subjects affected by a SARS-CoV-2-linked illness (COVID-19) also f
Externí odkaz:
https://doaj.org/article/55e9314822274d27aa985e4800b41313
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5698 (2024)
We present the case of a 70-year-old never-smoking female patient with epidermal growth factor receptor (EGFR) p.L858R-mutated metastatic non-small cell lung cancer (NSCLC). After three months of first-line treatment with erlotinib, progression occur
Externí odkaz:
https://doaj.org/article/fa1a13cfabc74891baf3dcb91e52df13
Autor:
Cristina Quintavalle, Nathalie Meyer‐Schaller, Stephanie Roessler, Diego Calabrese, Romina Marone, Tobias Riedl, Silvia Picco‐Rey, Orestis A. Panagiotou, Sarp Uzun, Salvatore Piscuoglio, Tuyana Boldanova, Chaoran B. Bian, David Semela, Wolfram Jochum, Gieri Cathomas, Kirsten D. Mertz, Joachim Diebold, Luca Mazzucchelli, Viktor H. Koelzer, Achim Weber, Thomas Decaens, Luigi M. Terracciano, Mathias Heikenwalder, Yujin Hoshida, Jesper B. Andersen, Snorri S. Thorgeirsson, Matthias S. Matter
Publikováno v:
Hepatology Communications, Vol 6, Iss 6, Pp 1467-1481 (2022)
Chronic liver inflammation causes continuous liver damage with progressive liver fibrosis and cirrhosis, which may eventually lead to hepatocellular carcinoma (HCC). Whereas the 10‐year incidence for HCC in patients with cirrhosis is approximately
Externí odkaz:
https://doaj.org/article/baec932dd7004118b6b3ef62cac7625e
Autor:
Antonio Rodriguez-Calero, John Gallon, Dilara Akhoundova, Sina Maletti, Alison Ferguson, Joanna Cyrta, Ursula Amstutz, Andrea Garofoli, Viola Paradiso, Scott A. Tomlins, Ekkehard Hewer, Vera Genitsch, Achim Fleischmann, Erik Vassella, Elisabeth J. Rushing, Rainer Grobholz, Ingeborg Fischer, Wolfram Jochum, Gieri Cathomas, Adeboye O. Osunkoya, Lukas Bubendorf, Holger Moch, George Thalmann, Charlotte K. Y. Ng, Silke Gillessen, Salvatore Piscuoglio, Mark A. Rubin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The diagnosis of prostate cancer brain metastasis (PCBM) has increased. Here, the authors investigate the landscape of somatic genetic alterations in brain metastases in a PCBM cohort of 51 patients with non-synchronous matched primary samples availa
Externí odkaz:
https://doaj.org/article/42966ddd44de4ed4a87861f3d4c3176c
Autor:
Lipin Loo, Matthew A Waller, Cesar L Moreno, Alexander J Cole, Alberto Ospina Stella, Oltin-Tiberiu Pop, Ann-Kristin Jochum, Omar Hasan Ali, Christopher E Denes, Zina Hamoudi, Felicity Chung, Anupriya Aggarwal, Jason K K Low, Karishma Patel, Rezwan Siddiquee, Taeyoung Kang, Suresh Mathivanan, Joel P Mackay, Wolfram Jochum, Lukas Flatz, Daniel Hesselson, Stuart Turville, G Gregory Neely
Publikováno v:
PLoS Biology, Vol 21, Iss 2, p e3001967 (2023)
Although ACE2 is the primary receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, a systematic assessment of host factors that regulate binding to SARS-CoV-2 spike protein has not been described. Here, we use whole-gen
Externí odkaz:
https://doaj.org/article/a8987683bf0d45a6a15d82980b6d7c2c
Autor:
Holger Moch, Gieri Cathomas, Milo Frattini, Wolfram Jochum, Erik Vassella, Laurence de Leval, Joachim Diebold, Christian Britschgi, Thomas McKee, Lukas Bubendorf
Publikováno v:
healthbook TIMES. Oncology Hematology, Vol 1, Iss 7, Pp 14-21 (2021)
In May 2020, larotrectinib (Vitrakvi®) was approved as the first tumor-agnostic agent in Switzerland for the treatment of adult and pediatric patients with solid tumors that have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion. While in c
Externí odkaz:
https://doaj.org/article/cd0f6a5afccc4310b9147d52ed3cf998
Autor:
Vittoria Guarda, Lea Schroeder, Michael Pawlita, Kristian Ikenberg, Niels J. Rupp, Wolfram Jochum, Sandro J. Stoeckli, Dana Holzinger, Martina A. Broglie
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesThe natural history of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) is still largely unknown. Since reports of second primary tumors (SPTs) in patients with HPV-related OPSCCs are increasing, a multifocal HPV infection, hinting
Externí odkaz:
https://doaj.org/article/475f9d131e5b4f87a242d7398cfb716c