Zobrazeno 1 - 10
of 113 835
pro vyhledávání: '"Wolfram"'
Autor:
Wolfram Höps, Tobias Rausch, Michael Jendrusch, Human Genome Structural Variation Consortium (HGSVC), Jan O. Korbel, Fritz J. Sedlazeck
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Modern sequencing technology enables the systematic detection of complex structural variation (SV) across genomes. However, extensive DNA rearrangements arising through a series of mutations, a phenomenon we refer to as serial SV (sSV), rema
Externí odkaz:
https://doaj.org/article/4c219d508eba43c292207434962da475
Autor:
Julia Holzgruber, Christina Martins, Zsofi Kulcsar, Alexandra Duplaine, Erik Rasbach, Laure Migayron, Praveen Singh, Edith Statham, Jennifer Landsberg, Katia Boniface, Julien Seneschal, Wolfram Hoetzenecker, Emma L. Berdan, Shannan Ho Sui, Matthew R. Ramsey, Steven R. Barthel, Tobias Schatton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Programmed cell death 1 (PD-1) is a premier cancer drug target for immune checkpoint blockade (ICB). Because PD-1 receptor inhibition activates tumor-specific T-cell immunity, research has predominantly focused on T-cell-PD-1 expression and
Externí odkaz:
https://doaj.org/article/209ec2809d724247864f9587c7cce533
Publikováno v:
Journal of High Energy Physics, Vol 2024, Iss 8, Pp 1-37 (2024)
Abstract In an external electric or magnetic field, a gravitational wave (GW) may be converted into electromagnetic radiation. We present a coordinate-invariant framework to describe the GW signal in a detector that is based on this effect, such as c
Externí odkaz:
https://doaj.org/article/c2f8b7ee54fc4022a9db4d115ca8faa5
Autor:
Melanie Berger, Falk Schumacher, Maximilian Wollsching-Strobel, Doreen Kroppen, Sarah B. Stanzel, Daniel S. Majorski, Kathrin Fricke, Ilka Plath, Wolfram Windisch, Maximilian Zimmermann
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-6 (2024)
Abstract Introduction VEXAS syndrome, characterized by a UBA1 gene mutation, is a rare and severe systemic inflammatory disease predominantly affecting men. Since its initial description in 2020, it has been noted for its broad clinical phenotype and
Externí odkaz:
https://doaj.org/article/3d48f5508b32495798d4726642812e1b
Autor:
Pia Teufl, Wolfram Graf
Publikováno v:
Biodiversity Data Journal, Vol 12, Iss , Pp 1-10 (2024)
Although studies of the entomofauna of the Balkan Peninsula have increased in quantity and intensity over the course of the last decades, many areas are still not fully investigated regarding their faunistic inventory.As a result of a field trip in t
Externí odkaz:
https://doaj.org/article/f5befed6195b4c8daa5dbd4710c2b198
Autor:
Ioannis Kafetzis, Karl-Hermann Fuchs, Philipp Sodmann, Joel Troya, Wolfram Zoller, Alexander Meining, Alexander Hann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Standardized assessment of the gastroesophageal valve during endoscopy, attainable via the Hill classification, is important for clinical assessment and therapeutic decision making. The Hill classification is associated with the presence of
Externí odkaz:
https://doaj.org/article/d37369e713454adfb7d9d14eb601dca3
Young people’s trust in institutions, civic knowledge and their dispositions toward civic engagement
Autor:
Wolfram Schulz
Publikováno v:
Large-scale Assessments in Education, Vol 12, Iss 1, Pp 1-30 (2024)
Abstract Recent years have witnessed signs of increasing political instability in democratic countries as well as growing alienation from civic institutions and processes among citizens, especially among young people. Within the context of civic and
Externí odkaz:
https://doaj.org/article/42e53ec6d6b74e5590090b6530a2a2df
Autor:
Matthew Hunt, Nuoqi Wang, Naricha Pupinyo, Philip Curman, Monica Torres, William Jebril, Maria Chatzinikolaou, Julie Lorent, Gilad Silberberg, Ritu Bansal, Teresa Burner, Jing Zhou, Susanne Kimeswenger, Wolfram Hoetzenecker, Keith Choate, Etty Bachar-Wikstrom, Jakob D Wikstrom
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 1986-2001 (2024)
Abstract Darier disease (DD) is a rare severe acantholytic skin disease caused by mutations in the ATP2A2 gene that encodes for the sarco/endoplasmic reticulum calcium ATPase isoform 2 (SERCA2). SERCA2 maintains endoplasmic reticulum calcium homeosta
Externí odkaz:
https://doaj.org/article/b20f15a21d914c2e8a2d537249034dd9
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Tuberculosis (TB) causes major public health problems worldwide. Fighting TB requires sustained efforts in health prevention, diagnosis and treatment. Previous literature has shown that conventional diagnostic methods like X-ray and sputum m
Externí odkaz:
https://doaj.org/article/e016754f0cb043a095d3e562e9de2324
Autor:
John Ainley, Wolfram Schulz
Publikováno v:
Large-scale Assessments in Education, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Religious attachment has been identified as an important correlate of civic participation, civic engagement, and civil participation among adults. This study investigates two aspects of relationships between religiosity and intended politica
Externí odkaz:
https://doaj.org/article/c1f4a48e03b84d7195e9c5a1e4b70bfb