Výsledky vyhledávání - "Wolfgang Weidemann"

Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults

Autor: Katrin Hille, Sanna Stroth, Matthias Schneider, Sascha Härtel, Klaus Bös, Manfred Spitzer, Wolfgang Weidemann, Ralf Reinhardt, Jan Thöne

Publikováno v: Neurobiology of Learning and Memory. 94:364-372

Physical fitness can serve as a means to enhance cognitive functioning by modulating particular aspects of brain functioning. However, mechanisms underlying this modulating effect remain widely unresolved. To examine the impact and to clarify the mec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184dc191dd4dfa2520992211b8f5ca2f
https://doi.org/10.1016/j.nlm.2010.08.003

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Genital Skin Fibroblasts (GF) of Patients with Androgen Insensitivity Syndrome Express Higher Insulin-Like Growth Factor Binding Protein (IGFBP)-2, -3 and -5 than GF of Normally Virilized Males

Autor: B.S. Schuett, Wolfgang Weidemann, Gabriela Romalo, Martin W. Elmlinger, Michael B. Ranke, D. Diesing, H.U. Schweikert, Klaus-Dieter Spindler

Publikováno v: Hormone Research in Paediatrics. 60:73-78

Background: We investigated the effects of androgens, estradiol (E2) and insulin-like growth factor (IGF)-I on IGF-II, insulin-like growth factor binding protein (IGFBP)-2, -3 and -5 and mRNA in genital fibroblasts (GF) from patients with complete an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5dcca52d2de1c620933b27ddc98126
https://doi.org/10.1159/000071874

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Hypospadie: Klinik, Endokrinologie und molekularbiologische Aspekte

Autor: Gabriela Romalo, Wolfgang Weidemann, H.U. Schweikert, Klaus-Dieter Spindler

Publikováno v: Reproduktionsmedizin. 17:170-176

Obwohl die Hypospadie zu den haufigsten mannlichen kongenitalen Storungen zahlt, sind die kausalen Ursachen dieser Fehlbildungen haufig unbekannt. Dies liegt vermutlich daran, dass fur die Differenzierung des Penis eine Vielzahl von Faktoren in Frage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4790c59b57819f04c0b39f31614c411e
https://doi.org/10.1007/s004440100265

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A cDNA encoding a chitinase from the epithelial cell line ofChironomus tentans(Insecta, Diptera) and its functional expression

Autor: Klaus-Dieter Spindler, Margarethe Spindler-Barth, Sabine Glöggler, Michael Londershausen, Maritta Feix, Wolfgang Weidemann

Publikováno v: Archives of Insect Biochemistry and Physiology. 45:24-36

A cDNA coding for chitinase was isolated from Chironomus cells, which possesses conserved regions I and II characteristic for family 18 chitinases, a C-terminus enriched in Glu and Pro without the typical "PEST-region," putative glycosylation sites,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be6a3a8d6ee4a78912b33504822507ba
https://doi.org/10.1002/1520-6327(200009)45:1<24::aid-arch3>3.0.co

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The exon–intron organization of the prohormone convertase PC2 gene from the insect Lucilia cuprina

Autor: Birgit Mentrup, Wolfgang Weidemann

Publikováno v: Gene. 237:29-33

Prohormone or proprotein convertases are members of the subtilisin family of serine proteases. They are involved in the activation of precursor molecules by endoproteolytic cleavage at basic amino acid residues. Among the different members of this pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01a041ff702e79f920156ff85669ae4
https://doi.org/10.1016/s0378-1119(99)00326-1

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Isolation and characterization of insect PC2-like prohormone convertase cDNA

Autor: Wolfgang Weidemann, Michael Londershausen, B. Mentrup, Klaus-Dieter Spindler

Publikováno v: Insect Molecular Biology. 8:305-310

Endoproteolytic processing of large precursor molecules at basic amino acid residues plays an important role in the maturation of many hormones, neuropeptides and other regulatory proteins. Enzymes performing these reactions are designated as prohorm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273c931e7ad56da6ce5f707d193f3951
https://doi.org/10.1046/j.1365-2583.1999.83113.x

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An androgen receptor mutation in the direct vicinity of the proposed C-terminal α-helix of the ligand binding domain containing the AF-2 transcriptional activating function core is associated with complete androgen insensitivity

Autor: Wolfgang Weidemann, D. Knorr, I. Peters, Klaus-Dieter Spindler, Gabriela Romalo, H.U. Schweikert

Publikováno v: Molecular and Cellular Endocrinology. 148:47-53

Subjects with androgen insensitivity syndromes (AIS) are characterized by a 46, XY karyotype, presence of testes, normal or elevated androgen levels in blood, and impairment of the usual response to androgens associated with various abberrations of m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c39bdba579211a7a41d5e6d9ff04c4
https://doi.org/10.1016/s0303-7207(98)00237-8

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Response to Androgen Treatment in a Patient with Partial Androgen Insensitivity and a Mutation in the Deoxyribonucleic Acid-Binding Domain of the Androgen Receptor1

Autor: Klaus-Dieter Spindler, Wolfgang Weidemann, Hans-Udo Schweikert, Birgit Peters, Gabriela Romalo

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 83:1173-1176

Supplemental androgen therapy has enhanced virilization in only a few patients with partial androgen insensitivity (PAIS). We herein report on virilization in a patient with PAIS and a point mutation in the DNA-binding domain of the androgen receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1b440f1b0c375ccc166cbbe6d80e24b
https://doi.org/10.1210/jcem.83.4.4704

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Clinical and biochemical investigations and molecular analysis of subjects with mutations in the androgen receptor gene

Autor: Albert O. Brinkmann, Heike Haupt, Hans-Udo Schweikert, Klaus-Dieter Spindler, Gabriela Romalo, Karin Stockklauser, Wolfgang Weidemann, Birgit Linck, Birgit Mentrup

Publikováno v: Clinical Endocrinology. 45:733-739

OBJECTIVE Androgen insensitivity syndromes (AIS) in subjects with 46,XY karyotype and normal or even elevated androgen blood levels are characterized by various aberrations in male differentiation and virilization. AIS is often accompanied by a broad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cd1b74d965e948ff6b63beb083a973
https://doi.org/10.1046/j.1365-2265.1996.8600869.x

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AR-Q640X, a model to study the effects of constitutively active C-terminally truncated AR variants in prostate cancer cells

Autor: Martin Laschak, Mark Schrader, Michael Höpfner, Florian Jentzmik, Wolfgang Streicher, Wolfgang Weidemann, Friedemann Zengerling, Marcus V. Cronauer, Andres Jan Schrader

Publikováno v: World journal of urology. 30(3)

A recently identified mechanism allowing prostate cancer (PCa) cells to grow in the absence of androgens is the expression of constitutively active, C-terminally truncated androgen receptor (AR) variants lacking vast parts of the ligand-binding domai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a8318279e400d449542391aa343676
https://pubmed.ncbi.nlm.nih.gov/22362413

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