Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Wolfgang Urfer"'
Autor:
Klaus Jung, Ali Gannoun, Barbara Sitek, Ognjan Apostolov, Alexander Schramm, Helmut E. Meyer, Kai Stühler, Wolfgang Urfer
Publikováno v:
Revstat Statistical Journal, Vol 4, Iss 1 (2006)
In this article, we analyze time dependent protein expression data obtained from a proteome study of a neuroblastoma cell line. Neuroblastoma are common solid tumors which occur in early childhood. The expression data was obtained by difference gel e
Externí odkaz:
https://doaj.org/article/13a6befd07044f74934e3e2bd9d7db6a
Publikováno v:
Revstat Statistical Journal, Vol 3, Iss 2 (2005)
Difference gel electrophoresis (DIGE) is the new gold standard analysing complex protein mixtures in proteomics. It is used for measuring the expression levels of proteins in different mixtures on the same two-dimensional electrophoresis (2-DE) gel.
Externí odkaz:
https://doaj.org/article/e22676571ebb4a70b168731e6b15008c
Publikováno v:
International Journal for Ion Mobility Spectrometry. 11:43-49
This study has developed an efficient preprocessing strategy for ion mobility spectrometry (IMS) data allowing for improved peak clarity and comparability of different measurements. Using the discrete wavelet transform for data compression and denois
Publikováno v:
PROTEOMICS. 6:48-55
Most proteomics experiments make use of 'high throughput' technologies such a's 2-DE, MS or protein arrays to measure simultaneously the expression levels of thousands of proteins. Such experiments yield, large, high-dimensional data sets which usual
Publikováno v:
Journal of Chemometrics. 20:128-135
Spectrometric methods generate a large amount of data that are difficult to process due to high dimensionality and considerable variability. Therefore, a method for the detection of characteristic peak structures was established on the base of cluste
Autor:
Nadine Kutzner, Marco Grzegorczyk, Klaus-Michael Müller, Ingrid Hoffmann, Oliver Müller, Gerd Hohlbach, Wolfgang Urfer, Cornelius Kuhnen, Günther Winde, Dirk Martin, Thilo Traska, Thomas Thienel, Christina Linke
Publikováno v:
Cancer Letters. 229:33-41
The treatment of early-stage tumours decreases the overall mortality of colorectal tumour patients. In this retrospective study we determined the sensitivity and the specificity of the faecal occult blood test (FOBT) and the molecular diagnosis (MD).
Autor:
K. Emrich, Wolfgang Urfer
Publikováno v:
Euphytica. 137:155-163
Normal mixtures are applied in interval mapping to model the segregation of genotypes following Mendel's Law in successive generations of crossing. Standard methods use least squares or maximum likelihood estimates. Theoretically, maximum likelihood
Publikováno v:
Environmental and Ecological Statistics. 7:43-56
In most real data situations in the one-way design both the underlying distribution and the shape of the dose-response curve are a priori unknown. The power of a trend test strongly depends on both. However, tests which are routinely used to analyze
Publikováno v:
Environmetrics. 11:479-495
The determination of toxicokinetic parameters is an essential component in the risk assessment of potential harmful chemicals. It is a key step to analyse the processes involved in the formation of DNA adducts which are connected with the development
Publikováno v:
Environmetrics. 10:633-654
Fluctuation of the groundwater level in karstic areas results from different cumulative effects, such as water infiltration from precipitation, human interference on the water resources of a certain area, the Moon's tide effect, air pressure fluctuat